Structure of Streptomyces maltosyltransferase GlgE, a homologue of a genetically validated anti-tuberculosis target

Journal of Biological Chemistry

Volumn 286, Issue 44, 2011, Pages 38298-38310

  Syson, Karl ^a   Stevenson, Clare E M ^a   Rejzek, Martin ^a   Fairhurst, Shirley A ^a   Nair, Alap ^a   Bruton, Celia J ^a   Field, Robert A ^a   Chater, Keith F ^a   Lawson, David M ^a   Bornemann, Stephen ^a  

^a JOHN INNES CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG TARGETS; HELIX BUNDLE; HOMODIMERS; HYDROPHOBIC PATCH; ISOFORMS; KINETIC PROPERTIES; M. TUBERCULOSIS; MALTOOLIGOSACCHARIDES; MYCOBACTERIUM TUBERCULOSIS; S. COELICOLOR; STREPTOMYCES COELICOLOR; THERAPEUTIC POTENTIALS;

BACTERIA; BIOCHEMISTRY; CYCLODEXTRINS; ENZYMES; HYDROPHOBICITY; MALTOSE;

CRYSTAL STRUCTURE;

AMYLASE; BACTERIAL ENZYME; CYCLODEXTRIN; GLGE PROTEIN; MALTOSE; MALTOSE OLIGOSACCHARIDE; MALTOSYLTRANSFERASE; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBUNIT; HYDROPHOBICITY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; STREPTOMYCES COELICOLOR;

ANTITUBERCULAR AGENTS; BINDING SITES; CATALYSIS; GLUCOSYLTRANSFERASES; GLYCOSIDE HYDROLASES; KINETICS; MALTOSE; MODELS, CHEMICAL; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN ISOFORMS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STREPTOMYCES;

MYCOBACTERIUM TUBERCULOSIS; STREPTOMYCES; STREPTOMYCES COELICOLOR;

EID: 80055084613     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.279315     Document Type: Article

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