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Volumn 5, Issue 3, 2014, Pages

Lipopolysaccharide differentially affects the osteogenic differentiation of periodontal ligament stem cells and bone marrow mesenchymal stem cells through Toll-like receptor 4 mediated nuclear factor κb pathway

Author keywords

[No Author keywords available]

Indexed keywords

ALIZARIN RED S; ALKALINE PHOSPHATASE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR RUNX2; LIPOPOLYSACCHARIDE; TLR4 PROTEIN, HUMAN;

EID: 84902315454     PISSN: None     EISSN: 17576512     Source Type: Journal    
DOI: 10.1186/scrt456     Document Type: Article
Times cited : (130)

References (43)
  • 1
    • 49449108585 scopus 로고    scopus 로고
    • The management of inflammation in periodontal disease
    • 10.1902/jop.2008.080173 18673016
    • The management of inflammation in periodontal disease. Van Dyke TE, J Periodontol 2008 79 1601 1608 10.1902/jop.2008.080173 18673016
    • (2008) J Periodontol , vol.79 , pp. 1601-1608
    • Van Dyke, T.E.1
  • 2
    • 0035287559 scopus 로고    scopus 로고
    • Periodontal manifestations of systemic disease
    • Periodontal manifestations of systemic disease. Kinane DF, Marshall GJ, Aust Dent J 2001 46 2 12 10.1111/j.1834-7819.2001.tb00267.x 11355236 (Pubitemid 33637041)
    • (2001) Australian Dental Journal , vol.46 , Issue.1 , pp. 2-12
    • Kinane, D.F.1    Marshall, G.J.2
  • 3
    • 0023073672 scopus 로고
    • Functional characterization of extracellular vesicles produced by Bacteroides gingivalis
    • Functional characterization of extracellular vesicles produced by Bacteroides gingivalis. Grenier D, Mayrand D, Infect Immun 1987 55 111 117 3539799 (Pubitemid 17220373)
    • (1987) Infection and Immunity , vol.55 , Issue.1 , pp. 111-117
    • Grenier, D.1    Mayrand, D.2
  • 4
    • 33947356654 scopus 로고    scopus 로고
    • Functional TLRs and NODs in human gingival fibroblasts
    • 10.1177/154405910708600310 17314257
    • Functional TLRs and NODs in human gingival fibroblasts. Uehara A, Takada H, J Dent Res 2007 86 249 254 10.1177/154405910708600310 17314257
    • (2007) J Dent Res , vol.86 , pp. 249-254
    • Uehara, A.1    Takada, H.2
  • 5
    • 0037317763 scopus 로고    scopus 로고
    • Innate immune sensing and its roots: The story of endotoxin
    • DOI 10.1038/nri1004
    • Innate immune sensing and its roots: the story of endotoxin. Beutler B, Rietschel ET, Nat Rev Immunol 2003 3 169 176 10.1038/nri1004 12563300 (Pubitemid 37328694)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.2 , pp. 169-176
    • Beutler, B.1    Rietschel, E.Th.2
  • 6
    • 77953616099 scopus 로고    scopus 로고
    • Periodontitis: A polymicrobial disruption of host homeostasis
    • 10.1038/nrmicro2337 20514045
    • Periodontitis: a polymicrobial disruption of host homeostasis. Darveau RP, Nat Rev Microbiol 2010 8 481 490 10.1038/nrmicro2337 20514045
    • (2010) Nat Rev Microbiol , vol.8 , pp. 481-490
    • Darveau, R.P.1
  • 7
    • 3042749378 scopus 로고    scopus 로고
    • Investigation of multipotent postnatal stem cells from human periodontal ligament
    • DOI 10.1016/S0140-6736(04)16627-0, PII S0140673604166270
    • Investigation of multipotent postnatal stem cells from human periodontal ligament. Seo BM, Miura M, Gronthos S, Bartold PM, Batouli S, Brahim J, Young M, Robey PG, Wang CY, Shi S, Lancet 2004 364 149 155 10.1016/S0140-6736(04)16627-0 15246727 (Pubitemid 38891686)
    • (2004) Lancet , vol.364 , Issue.9429 , pp. 149-155
    • Seo, B.-M.1    Miura, M.2    Gronthos, S.3    Bartold, P.M.4    Batouli, S.5    Brahim, J.6    Young, M.7    Robey, P.G.8    Wang, C.-Y.9    Shi, S.10
  • 8
    • 49249088145 scopus 로고    scopus 로고
    • Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine
    • 10.1634/stemcells.2007-0734 18238856
    • Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine. Liu Y, Zheng Y, Ding G, Fang D, Zhang C, Bartold PM, Gronthos S, Shi S, Wang S, Stem Cells 2008 26 1065 1073 10.1634/stemcells.2007-0734 18238856
    • (2008) Stem Cells , vol.26 , pp. 1065-1073
    • Liu, Y.1    Zheng, Y.2    Ding, G.3    Fang, D.4    Zhang, C.5    Bartold, P.M.6    Gronthos, S.7    Shi, S.8    Wang, S.9
  • 9
    • 78149317968 scopus 로고    scopus 로고
    • Allogeneic periodontal ligament stem cell therapy for periodontitis in swine
    • 10.1002/stem.512 20979138
    • Allogeneic periodontal ligament stem cell therapy for periodontitis in swine. Ding G, Liu Y, Wang W, Wei F, Liu D, Fan Z, An Y, Zhang C, Wang S, Stem Cells 2010 28 1829 1838 10.1002/stem.512 20979138
    • (2010) Stem Cells , vol.28 , pp. 1829-1838
    • Ding, G.1    Liu, Y.2    Wang, W.3    Wei, F.4    Liu, D.5    Fan, Z.6    An, Y.7    Zhang, C.8    Wang, S.9
  • 10
    • 7044263352 scopus 로고    scopus 로고
    • Enhancement of periodontal tissue regeneration by transplantation of bone marrow mesenchymal stem cells
    • DOI 10.1902/jop.2004.75.9.1281
    • Enhancement of periodontal tissue regeneration by transplantation of bone marrow mesenchymal stem cells. Kawaguchi H, Hirachi A, Hasegawa N, Iwata T, Hamaguchi H, Shiba H, Takata T, Kato Y, Kurihara H, J Periodontol 2004 75 1281 1287 10.1902/jop.2004.75.9.1281 15515346 (Pubitemid 39419730)
    • (2004) Journal of Periodontology , vol.75 , Issue.9 , pp. 1281-1287
    • Kawaguchi, H.1    Hirachi, A.2    Hasegawa, N.3    Iwata, T.4    Hamaguchi, H.5    Shiba, H.6    Takata, T.7    Kato, Y.8    Kurihara, H.9
  • 11
    • 77957319467 scopus 로고    scopus 로고
    • Periodontal regeneration using engineered bone marrow mesenchymal stromal cells
    • 10.1016/j.biomaterials.2010.06.026 20832109
    • Periodontal regeneration using engineered bone marrow mesenchymal stromal cells. Yang Y, Rossi FM, Putnins EE, Biomaterials 2010 31 8574 8582 10.1016/j.biomaterials.2010.06.026 20832109
    • (2010) Biomaterials , vol.31 , pp. 8574-8582
    • Yang, Y.1    Rossi, F.M.2    Putnins, E.E.3
  • 12
    • 84863589190 scopus 로고    scopus 로고
    • Stem cell-delivery therapeutics for periodontal tissue regeneration
    • 10.1016/j.biomaterials.2012.05.048 22695066
    • Stem cell-delivery therapeutics for periodontal tissue regeneration. Chen FM, Sun HH, Lu H, Yu Q, Biomaterials 2012 33 6320 6344 10.1016/j.biomaterials. 2012.05.048 22695066
    • (2012) Biomaterials , vol.33 , pp. 6320-6344
    • Chen, F.M.1    Sun, H.H.2    Lu, H.3    Yu, Q.4
  • 13
    • 84855341781 scopus 로고    scopus 로고
    • Expression of toll-like receptors 2, 4 and 9 is increased in gingival tissue from patients with type 2 diabetes and chronic periodontitis
    • 21848608
    • Expression of toll-like receptors 2, 4 and 9 is increased in gingival tissue from patients with type 2 diabetes and chronic periodontitis. Rojo-Botello NR, Garcia-Hernandez AL, Moreno-Fierros L, J Periodontal Res 2011 47 62 73 21848608
    • (2011) J Periodontal Res , vol.47 , pp. 62-73
    • Rojo-Botello, N.R.1    Garcia-Hernandez, A.L.2    Moreno-Fierros, L.3
  • 15
    • 54049148607 scopus 로고    scopus 로고
    • Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitors
    • 10.1186/1471-2121-9-52 18799018
    • Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitors. Mo IF, Yip KH, Chan WK, Law HK, Lau YL, Chan GC, BMC Cell Biol 2008 9 52 10.1186/1471-2121-9-52 18799018
    • (2008) BMC Cell Biol , vol.9 , pp. 52
    • Mo, I.F.1    Yip, K.H.2    Chan, W.K.3    Law, H.K.4    Lau, Y.L.5    Chan, G.C.6
  • 16
    • 84911808355 scopus 로고    scopus 로고
    • Inflammation and Toll-like receptor ligation differentially affect the osteogenic potential of human mesenchymal stromal cells depending on their tissue origin
    • 10.1089/ten.tea.2011.0434 22429150
    • Inflammation and Toll-like receptor ligation differentially affect the osteogenic potential of human mesenchymal stromal cells depending on their tissue origin. Raicevic G, Najar M, Pieters K, De Bruyn C, Meuleman N, Bron D, Toungouz M, Lagneaux L, Tissue Eng Part A 2012 18 1410 1418 10.1089/ten.tea. 2011.0434 22429150
    • (2012) Tissue Eng Part A , vol.18 , pp. 1410-1418
    • Raicevic, G.1    Najar, M.2    Pieters, K.3    De Bruyn, C.4    Meuleman, N.5    Bron, D.6    Toungouz, M.7    Lagneaux, L.8
  • 18
    • 84864316892 scopus 로고    scopus 로고
    • The effect of aging on the pluripotential capacity and regenerative potential of human periodontal ligament stem cells
    • 10.1016/j.biomaterials.2012.06.032 22789721
    • The effect of aging on the pluripotential capacity and regenerative potential of human periodontal ligament stem cells. Zhang J, An Y, Gao LN, Zhang YJ, Jin Y, Chen FM, Biomaterials 2012 33 6974 6986 10.1016/j.biomaterials.2012. 06.032 22789721
    • (2012) Biomaterials , vol.33 , pp. 6974-6986
    • Zhang, J.1    An, Y.2    Gao, L.N.3    Zhang, Y.J.4    Jin, Y.5    Chen, F.M.6
  • 19
    • 0034888399 scopus 로고    scopus 로고
    • A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats
    • DOI 10.1902/jop.2001.72.8.1069
    • A combination of a chemically modified doxycycline and a bisphosphonate synergistically inhibits endotoxin-induced periodontal breakdown in rats. Llavaneras A, Ramamurthy NS, Heikkila P, Teronen O, Salo T, Rifkin BR, Ryan ME, Golub LM, Sorsa T, J Periodontol 2001 72 1069 1077 10.1902/jop.2001.72.8.1069 11525440 (Pubitemid 32762869)
    • (2001) Journal of Periodontology , vol.72 , Issue.8 , pp. 1069-1077
    • Llavaneras, A.1    Ramamurthy, N.S.2    Heikkila, P.3    Teronen, O.4    Salo, T.5    Rifkin, B.R.6    Ryan, M.E.7    Golub, L.M.8    Sorsa, T.9
  • 20
    • 10944271083 scopus 로고    scopus 로고
    • Effects of combined systemic administration of low-dose doxycycline and alendronate on endotoxin-induced periodontitis in rats
    • DOI 10.1902/jop.2004.75.11.1516
    • Effects of combined systemic administration of low-dose doxycycline and alendronate on endotoxin-induced periodontitis in rats. Buduneli E, Vardar S, Buduneli N, Berdeli AH, Turkoglu O, Baskesen A, Atilla G, J Periodontol 2004 75 1516 1523 10.1902/jop.2004.75.11.1516 15633329 (Pubitemid 40012336)
    • (2004) Journal of Periodontology , vol.75 , Issue.11 , pp. 1516-1523
    • Buduneli, E.1    Vardar, S.2    Buduneli, N.3    Berdeli, A.H.4    Turkoglu, O.5    Baskesen, A.6    Atilla, G.7
  • 21
    • 3142654210 scopus 로고    scopus 로고
    • Inferences, questions and possibilities in Toll-like receptor signalling
    • DOI 10.1038/nature02761
    • Inferences, questions and possibilities in Toll-like receptor signalling. Beutler B, Nature 2004 430 257 263 10.1038/nature02761 15241424 (Pubitemid 38902439)
    • (2004) Nature , vol.430 , Issue.6996 , pp. 257-263
    • Beutler, B.1
  • 22
    • 52449091206 scopus 로고    scopus 로고
    • Lipopolysaccharide (LPS) of Porphyromonas gingivalis induces IL-1beta, TNF-alpha and IL-6 production by THP-1 cells in a way different from that of Escherichia coli LPS
    • 10.1177/1753425907088244 18713726
    • Lipopolysaccharide (LPS) of Porphyromonas gingivalis induces IL-1beta, TNF-alpha and IL-6 production by THP-1 cells in a way different from that of Escherichia coli LPS. Diya Z, Lili C, Shenglai L, Zhiyuan G, Jie Y, Innate Immun 2008 14 99 107 10.1177/1753425907088244 18713726
    • (2008) Innate Immun , vol.14 , pp. 99-107
    • Diya, Z.1    Lili, C.2    Shenglai, L.3    Zhiyuan, G.4    Jie, Y.5
  • 23
    • 0036065342 scopus 로고    scopus 로고
    • Initial responses to endotoxins and Gram-negative bacteria
    • DOI 10.1016/S0009-8981(02)00180-8, PII S0009898102001808
    • Initial responses to endotoxins and Gram-negative bacteria. Heumann D, Roger T, Clin Chim Acta 2002 323 59 72 10.1016/S0009-8981(02)00180-8 12135807 (Pubitemid 34804795)
    • (2002) Clinica Chimica Acta , vol.323 , Issue.1-2 , pp. 59-72
    • Heumann, D.1    Roger, T.2
  • 24
    • 70349330316 scopus 로고    scopus 로고
    • Variable cell responses to P. Gingivalis lipopolysaccharide
    • 10.1177/0022034509341166 19734462
    • Variable cell responses to P. gingivalis lipopolysaccharide. Kocgozlu L, Elkaim R, Tenenbaum H, Werner S, J Dent Res 2009 88 741 745 10.1177/ 0022034509341166 19734462
    • (2009) J Dent Res , vol.88 , pp. 741-745
    • Kocgozlu, L.1    Elkaim, R.2    Tenenbaum, H.3    Werner, S.4
  • 25
    • 0036606913 scopus 로고    scopus 로고
    • Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster
    • DOI 10.1016/S1471-4906(02)02233-0, PII S1471490602022330
    • Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster. Triantafilou M, Triantafilou K, Trends Immunol 2002 23 301 304 10.1016/S1471-4906(02)02233-0 12072369 (Pubitemid 34628773)
    • (2002) Trends in Immunology , vol.23 , Issue.6 , pp. 301-304
    • Triantafilou, M.1    Triantafilou, K.2
  • 26
    • 80051670366 scopus 로고    scopus 로고
    • The source of human mesenchymal stromal cells influences their TLR profile as well as their functional properties
    • 10.1016/j.cellimm.2011.05.010 21700275
    • The source of human mesenchymal stromal cells influences their TLR profile as well as their functional properties. Raicevic G, Najar M, Stamatopoulos B, De Bruyn C, Meuleman N, Bron D, Toungouz M, Lagneaux L, Cell Immunol 2011 270 207 216 10.1016/j.cellimm.2011.05.010 21700275
    • (2011) Cell Immunol , vol.270 , pp. 207-216
    • Raicevic, G.1    Najar, M.2    Stamatopoulos, B.3    De Bruyn, C.4    Meuleman, N.5    Bron, D.6    Toungouz, M.7    Lagneaux, L.8
  • 27
    • 33845995756 scopus 로고    scopus 로고
    • Role of toll-like receptors on human adipose-derived stromal cells
    • DOI 10.1634/stemcells.2006-0189
    • Role of toll-like receptors on human adipose-derived stromal cells. Hwa Cho H, Bae YC, Jung JS, Stem Cells 2006 24 2744 2752 10.1634/stemcells.2006-0189 16902195 (Pubitemid 46053012)
    • (2006) Stem Cells , vol.24 , Issue.12 , pp. 2744-2752
    • Hyun, H.C.1    Yong, C.B.2    Jin, S.J.3
  • 30
    • 84875969826 scopus 로고    scopus 로고
    • Nuclear factor-kappaB modulates osteogenesis of periodontal ligament stem cells through competition with beta-catenin signaling in inflammatory microenvironments
    • 10.1038/cddis.2013.14 23449446
    • Nuclear factor-kappaB modulates osteogenesis of periodontal ligament stem cells through competition with beta-catenin signaling in inflammatory microenvironments. Chen X, Hu C, Wang G, Li L, Kong X, Ding Y, Jin Y, Cell Death Dis 2013 4 510 10.1038/cddis.2013.14 23449446
    • (2013) Cell Death Dis , vol.4 , pp. 5510
    • Chen, X.1    Hu, C.2    Wang, G.3    Li, L.4    Kong, X.5    Ding, Y.6    Jin, Y.7
  • 31
    • 67649450478 scopus 로고    scopus 로고
    • TNFalpha promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-kappaB signaling pathway
    • 10.1016/j.bone.2009.04.252 19414075
    • TNFalpha promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-kappaB signaling pathway. Hess K, Ushmorov A, Fiedler J, Brenner RE, Wirth T, Bone 2009 45 367 376 10.1016/j.bone.2009.04.252 19414075
    • (2009) Bone , vol.45 , pp. 367-376
    • Hess, K.1    Ushmorov, A.2    Fiedler, J.3    Brenner, R.E.4    Wirth, T.5
  • 33
    • 67349265173 scopus 로고    scopus 로고
    • Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: Implications for bone repair during inflammation
    • 10.1016/j.joca.2008.11.011 19136283
    • Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation. Lacey DC, Simmons PJ, Graves SE, Hamilton JA, Osteoarthritis Cartilage 2009 17 735 742 10.1016/j.joca.2008.11.011 19136283
    • (2009) Osteoarthritis Cartilage , vol.17 , pp. 735-742
    • Lacey, D.C.1    Simmons, P.J.2    Graves, S.E.3    Hamilton, J.A.4
  • 34
    • 79952122953 scopus 로고    scopus 로고
    • TNF-alpha promotes fracture repair by augmenting the recruitment and differentiation of muscle-derived stromal cells
    • 10.1073/pnas.1018501108 21209334
    • TNF-alpha promotes fracture repair by augmenting the recruitment and differentiation of muscle-derived stromal cells. Glass GE, Chan JK, Freidin A, Feldmann M, Horwood NJ, Nanchahal J, Proc Natl Acad Sci U S A 2011 108 1585 1590 10.1073/pnas.1018501108 21209334
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 1585-1590
    • Glass, G.E.1    Chan, J.K.2    Freidin, A.3    Feldmann, M.4    Horwood, N.J.5    Nanchahal, J.6
  • 35
    • 80053281947 scopus 로고    scopus 로고
    • Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1
    • 10.1002/stem.703 21809421
    • Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1. Zhao L, Huang J, Zhang H, Wang Y, Matesic LE, Takahata M, Awad H, Chen D, Xing L, Stem Cells 2011 29 1601 1610 10.1002/stem.703 21809421
    • (2011) Stem Cells , vol.29 , pp. 1601-1610
    • Zhao, L.1    Huang, J.2    Zhang, H.3    Wang, Y.4    Matesic, L.E.5    Takahata, M.6    Awad, H.7    Chen, D.8    Xing, L.9
  • 36
    • 34147132868 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells is an optimal approach for plastic surgery
    • DOI 10.1634/stemcells.2006-0576
    • Transplantation of mesenchymal stem cells is an optimal approach for plastic surgery. Fang D, Seo BM, Liu Y, Sonoyama W, Yamaza T, Zhang C, Wang S, Shi S, Stem Cells 2007 25 1021 1028 10.1634/stemcells.2006-0576 17170063 (Pubitemid 46572600)
    • (2007) Stem Cells , vol.25 , Issue.4 , pp. 1021-1028
    • Fang, D.1    Seo, B.-M.2    Liu, Y.3    Sonoyama, W.4    Yamaza, T.5    Zhang, C.6    Wang, S.7    Shi, S.8
  • 37
    • 80053405262 scopus 로고    scopus 로고
    • Successful periodontal ligament regeneration by periodontal progenitor preseeding on natural tooth root surfaces
    • 10.1089/scd.2010.0431 21250830
    • Successful periodontal ligament regeneration by periodontal progenitor preseeding on natural tooth root surfaces. Dangaria SJ, Ito Y, Luan X, Diekwisch TG, Stem Cells Dev 2011 20 1659 1668 10.1089/scd.2010.0431 21250830
    • (2011) Stem Cells Dev , vol.20 , pp. 1659-1668
    • Dangaria, S.J.1    Ito, Y.2    Luan, X.3    Diekwisch, T.G.4
  • 38
    • 84856595116 scopus 로고    scopus 로고
    • Toll-like receptors and their dual role in periodontitis: A review
    • 10.2334/josnusd.53.263 21959652
    • Toll-like receptors and their dual role in periodontitis: a review. Hans M, Hans VM, J Oral Sci 2011 53 263 271 10.2334/josnusd.53.263 21959652
    • (2011) J Oral Sci , vol.53 , pp. 263-271
    • Hans, M.1    Hans, V.M.2
  • 39
    • 0030801832 scopus 로고    scopus 로고
    • Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor
    • Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor. Abu-Amer Y, Ross FP, Edwards J, Teitelbaum SL, J Clin Invest 1997 100 1557 1565 10.1172/JCI119679 9294124 (Pubitemid 27425783)
    • (1997) Journal of Clinical Investigation , vol.100 , Issue.6 , pp. 1557-1565
    • Abu-Amer, Y.1    Ross, F.P.2    Edwards, J.3    Teitelbaum, S.L.4
  • 40
    • 0029198997 scopus 로고
    • Biological activities of lipopolysaccharides from oral bacteria and their relevance to the pathogenesis of chronic periodontitis
    • 7597416
    • Biological activities of lipopolysaccharides from oral bacteria and their relevance to the pathogenesis of chronic periodontitis. Wilson M, Sci Prog 1995 78 19 34 7597416
    • (1995) Sci Prog , vol.78 , pp. 19-34
    • Wilson, M.1
  • 41
    • 0035139792 scopus 로고    scopus 로고
    • Therapeutic potential of inhibition of the NF-κB pathway in the treatment of inflammation and cancer
    • Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. Yamamoto Y, Gaynor RB, J Clin Invest 2001 107 135 142 10.1172/JCI11914 11160126 (Pubitemid 32096826)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.2 , pp. 135-142
    • Yamamoto, Y.1    Gaynor, R.B.2
  • 42
    • 0030459341 scopus 로고    scopus 로고
    • 2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism of inhibition of NF kappa B by PDTC
    • 9003388
    • 2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism of inhibition of NF kappa B by PDTC. Brennan P, O'Neill LA, Biochem J 1996 320 975 981 9003388
    • (1996) Biochem J , vol.320 , pp. 975-981
    • Brennan, P.1    O'Neill, L.A.2
  • 43
    • 1042278138 scopus 로고    scopus 로고
    • Flavopiridol inhibits NF-κB activation induced by various carcinogens and inflammatory agents through inhibition of IκBα kinase and p65 phosphorylation. Abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9
    • DOI 10.1074/jbc.M304546200
    • Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9. Takada Y, Aggarwal BB, J Biol Chem 2004 279 4750 4759 14630924 (Pubitemid 38199070)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.6 , pp. 4750-4759
    • Takada, Y.1    Aggarwal, B.B.2


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