TNFα promotes osteogenic differentiation of human mesenchymal stem cells by triggering the NF-κB signaling pathway

Bone

Volumn 45, Issue 2, 2009, Pages 367-376

  Hess, Katrin ^a   Ushmorov, Alexey ^a   Fiedler, Jörg ^b   Brenner, Rolf E ^b   Wirth, Thomas ^a  

^a UNIVERSITY OF ULM   (Germany)

^b Department of Orthopedics   (Germany)

Author keywords

Bone morphogenic protein 2 (BMP 2); Matrix mineralization; Mesenchymal stem cells; Nuclear factor kappaB (NF B); Osteogenic differentiation

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; BONE MORPHOGENETIC PROTEIN 2; I KAPPA B KINASE; I KAPPA B KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ALKALINE PHOSPHATASE;

ARTICLE; BONE DEVELOPMENT; BONE MATRIX; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENETIC MANIPULATION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; MULTIPOTENT STEM CELL; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; ALLELE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; EXTRACELLULAR MATRIX; METABOLISM; RETROVIRUS; VIROLOGY;

ALKALINE PHOSPHATASE; ALLELES; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; EXTRACELLULAR MATRIX; HUMANS; I-KAPPA B KINASE; MESENCHYMAL STEM CELLS; NF-KAPPA B; OSTEOGENESIS; RETROVIRIDAE; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67649450478     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.04.252     Document Type: Article

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