Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome

International Journal of Cancer

Volumn 135, Issue 4, 2014, Pages 887-895

  Lim, Annette M ^a,b   Do, Hongdo ^a,c   Young, Richard J ^a   Wong, Stephen Q ^a   Angel, Christopher ^a,d   Collins, Marnie ^a   Takano, Elena A ^a   Corry, June ^a,b   Wiesenfeld, David ^b,d   Kleid, Stephen ^a   Sigston, Elizabeth ^e   Lyons, Bernard ^f   Fox, Stephen B ^a,b   Rischin, Danny ^a,b   Dobrovic, Alexander ^a,b,c   Solomon, Benjamin ^a,b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (Australia)

^d ROYAL MELBOURNE HOSPITAL   (Australia)

^e MONASH MEDICAL CENTRE   (Australia)

^f ST VINCENT S HOSPITAL   (Australia)

Author keywords

"tongue cancer," "oral cancer"; CDKN2A; FISH; methylation; mutation; p16

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A;

ADULT; AGE; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURGERY; CDKN2A GENE; COHORT ANALYSIS; CONTROLLED STUDY; COPY NUMBER VARIATION; CORRELATION ANALYSIS; DNA METHYLATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE INACTIVATION; GENE LOSS; GENE OVEREXPRESSION; GENE SEQUENCE; HEMIZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; ORAL TONGUE SQUAMOUS CELL CARCINOMA; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; SMOKING; TONGUE CARCINOMA;

" TONGUE CANCER," " ORAL CANCER"; CDKN2A; FISH; METHYLATION; MUTATION; P16;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; DNA, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P16; HOMOZYGOTE; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MIDDLE AGED; SEQUENCE ANALYSIS, DNA; TONGUE NEOPLASMS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84902296657     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28727     Document Type: Article

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