A monastrol-derived compound, LaSOM 63, inhibits ecto-5'nucleotidase/CD73 activity and induces apoptotic cell death of glioma cell lines

Anticancer Research

Volumn 34, Issue 4, 2014, Pages 1837-1842

  Figueiró, Fabrício ^a   Mendes, Franciane Brackmann ^a   Corbelini, Patricia Frasson ^a   Janarelli, Fernanda ^a   Jandrey, Elisa Helena Farias ^a   Russowsky, Dennis ^a   Eifler Lima, Vera Lucia ^a   Battastini, Ana Maria Oliveira ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Ecto 5'nucleotidase; Glioma; LaSOM 63; Monastrol

Indexed keywords

5' NUCLEOTIDASE; ANTINEOPLASTIC AGENT; DIMETHYL SULFOXIDE; ECTO 5' NUCLEOTIDASE; LASOM 63; MALACHITE GREEN; MONASTROL; UNCLASSIFIED DRUG; 5-ETHOXYCARBONYL-6-METHYL-4-(4-N,N-DIMETHYLAMINOPHENYL)-3,4-DIHYDROPYRIMIDIN-2-(1H)-THIONE; 5 ETHOXYCARBONYL 6 METHYL 4 (4 N,N DIMETHYLAMINOPHENYL) 3,4 DIHYDROPYRIMIDIN 2 (1H) THIONE; PYRIMIDINE DERIVATIVE; THIOKETONE;

ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL DEATH; CELL GROWTH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; FLOW CYTOMETRY; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HUMAN; IN VIVO STUDY; MTT ASSAY; NONHUMAN; RAT; TRYPAN BLUE ASSAY; ANIMAL; CELL CYCLE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ECTO-5'NUCLEOTIDASE; ENZYME ACTIVATION; GLIOMA; LASOM 63; METABOLISM; TUMOR CELL LINE;

ECTO-5'NUCLEOTIDASE; GLIOMA; LASOM 63; MONASTROL;

5'-NUCLEOTIDASE; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLIOMA; HUMANS; PYRIMIDINES; RATS; THIONES;

EID: 84902292720     PISSN: 02507005     EISSN: 17917530     Source Type: Journal    
DOI: None     Document Type: Article

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