Simultaneous determination of bioactive components of Radix Angelicae Sinensis-Radix Paeoniae Alba herb couple in rat plasma and tissues by UPLC-MS/MS and its application to pharmacokinetics and tissue distribution

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 963, Issue , 2014, Pages 29-39

  Luo, Niancui ^a   Li, Zhenhao ^a   Qian, Dawei ^a   Qian, Yefei ^a   Guo, Jianming ^a   Duan, Jin ao ^a   Zhu, Min ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Herb couple; Pharmacokinetics; Radix angelicae sinensis; Radix paeoniae alba; Tissue distribution; UPLC MS MS

Indexed keywords

BODY FLUIDS; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; HISTOLOGY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHANOL; PHARMACOKINETICS; PLANT EXTRACTS; PROTEINS; RATS;

HERB COUPLE; RADIX ANGELICAE; RADIX PAEONIAE ALBA; TISSUE DISTRIBUTIONS; UPLC-MS/MS;

TISSUE;

ALBIFLORIN; ANGELICA ROOT EXTRACT; CAFFEIC ACID; CLARITHROMYCIN; FERULIC ACID; LIGUSTILIDE; MONOBENZONE; PAEONIFLORIN; VANILLIC ACID; ANGELICAE SINENSIS EXTRACT; HERBACEOUS AGENT; PLANT EXTRACT;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CHINESE HERB; CHROMATOGRAPHY; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG STRUCTURE; ELECTROSPRAY; HERB; INTESTINE ABSORPTION; IONIZATION; LIMIT OF QUANTITATION; MALE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRECIPITATION; PRIORITY JOURNAL; QUALITY CONTROL; STUDENT T TEST; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; BLOOD; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PAEONIA; PROCEDURES; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; MALE; PAEONIA; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

EID: 84902271148     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2014.05.036     Document Type: Article

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