Simultaneous determination of five phenolic components and paeoniflorin in rat plasma by liquid chromatography-tandem mass spectrometry and pharmacokinetic study after oral administration of Cerebralcare granule®

Journal of Pharmaceutical and Biomedical Analysis

Volumn 86, Issue , 2013, Pages 82-91

  Wang, Xiang yang ^a   Ma, Xiao hui ^a,b   Li, Wei ^a   Chu, Yang ^a   Guo, Jia hua ^a   Li, Shu ming ^a   Wang, Jun mei ^a   Zhang, Hong chao ^a   Zhou, Shui ping ^a   Zhu, Yong hong ^a  

^a Tianjin Tasly Group Co Ltd   (China)

^b TIANJIN UNIVERSITY   (China)

Author keywords

Active components; Cerebralcare granule ; LC MS MS; Pharmacokinetics; Rat plasma

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETONITRILE; ANION; CAFFEIC ACID; CEREBRALCARE GRANULE; CHLORAMPHENICOL; CHLOROGENIC ACID; FERULIC ACID; HERBACEOUS AGENT; PAEONIFLORIN; PHENOL DERIVATIVE; PROTOCATECHUIC ACID; ROSMARINIC ACID; UNCLASSIFIED DRUG; WATER;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY;

ACTIVE COMPONENTS; CEREBRALCARE GRANULE(®); LC-MS/MS; PHARMACOKINETICS; RAT PLASMA;

ADMINISTRATION, ORAL; ANIMALS; BENZOATES; BRIDGED COMPOUNDS; CHROMATOGRAPHY, LIQUID; DRUGS, CHINESE HERBAL; GLUCOSIDES; MALE; PAEONIA; PHENOLS; RATS; RATS, WISTAR; TANDEM MASS SPECTROMETRY;

EID: 84884967209     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2013.07.042     Document Type: Article

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