Highly diastereoselective synthesis of spiro[cyclopropane-1,3′- indolin]-2′-ones via catalyst-free cyclopropanation using ethyl diazoacetate

Tetrahedron

Volumn 70, Issue 32, 2014, Pages 4709-4717

  Maurya, Ram Awatar ^a   Reddy, Chada Narsimha ^a   Mani, Geeta Sai ^a   Kapure, Jeevak Sopanrao ^a   Adiyala, Praveen Reddy ^a   Nanubolu, Jagadeesh Babu ^a   Singarapu, Kiran Kumar ^a   Kamal, Ahmed ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Cyclopropanation; Ethyl diazoacetate; Indolin 2 one; Spiro compounds; Stereoselective synthesis

Indexed keywords

ACETONITRILE; ALCOHOL; CYCLOPROPANE DERIVATIVE; DIAZOACETIC ACID ETHYL ESTER; DIETHYL 1' METHYL 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2,3 DICARBOXYLATE; DIETHYL 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2,3 DICARBOXYLATE; DIETHYL 5' BROMO 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2,3 DICARBOXYLATE; DIETHYL 5' CHLORO 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2,3 DICARBOXYLATE; DIETHYL 5' FLUORO 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2,3 DICARBOXYLATE; DIETHYL 5' NITRO 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2,3 DICARBOXYLATE; ETHYL 1' METHYL 3 (4 METHYLBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 1' METHYL 3 (4 NITROBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 2 (2 NAPHTHOYL) 1' METHYL 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 3 CARBOXYLATE; ETHYL 2 (2 NAPHTHOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 3 CARBOXYLATE; ETHYL 2 (NAPHTHOYL) 5' CHLORO 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 3 CARBOXYLATE; ETHYL 2 BENZOYL 1' METHYL 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 3 CARBOXYLATE; ETHYL 2 BENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 3 CARBOXYLATE; ETHYL 2' OXO 3 (3,4,5 TRIMETHOXYBENZOYL)SPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 3 (4 CHLOROBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 3 (4 METHOXY 3 NITROBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 3 (4 METHOXYBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 3 (4 NITROBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 5' CHLORO 2' OXO 3 (3,4,5 TRIMETHOXYBENZOYL)SPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 5' CHLORO 3 (3,4 DIMETHYLBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 5' CHLORO 3 (4 CHLOROBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 5' CHLORO 3 (4 METHYLBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; ETHYL 5' CHLORO 3 (4 NITROBENZOYL) 2' OXOSPIRO[CYCLOPROPANE 1,3' INDOLINE] 2 CARBOXYLATE; SPIRO COMPOUND; SPIRO[CYCLOPROPANE 1,3' INDOLIN] 2' ONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYST; CYCLOPROPANATION; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION TIME; STEREOCHEMISTRY;

EID: 84902269550     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2014.05.065     Document Type: Article

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