-
1
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 1956;123: 309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
2
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ.Why do cancers have high aerobic glycolysis? Nat Rev Cancer 2004;4:891-899.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
3
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutaminemetabolismthat exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB. Beyond aerobic glycolysis: transformed cells can engage in glutaminemetabolismthat exceeds the requirement for protein and nucleotide synthesis. ProcNatlAcad Sci USA 2007;104:19345-19350.
-
(2007)
ProcNatlAcad Sci USA
, vol.104
, pp. 19345-19350
-
-
Deberardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
Thompson, C.B.7
-
4
-
-
57749088701
-
Myc regulates a transcriptional programthat stimulates mitochondrial glutaminolysis and leads to glutamine addiction
-
WiseDR,DeBerardinis RJ,Mancuso A, Sayed N, Zhang XY, PfeifferHK, Nissim I,Daikhin E, YudkoffM,McMahon SB,Thompson CB.Myc regulates a transcriptional programthat stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proc Natl Acad Sci USA 2008;105:18782-18787.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18782-18787
-
-
Wise, D.R.1
Deberardinis, R.J.2
Mancuso, A.3
Sayed, N.4
Zhang, X.Y.5
Pfeiffer, H.K.6
Nissim, I.7
Daikhin, E.8
Yudkoff, M.9
McMahon, S.B.10
Thompson, C.B.11
-
5
-
-
70349290632
-
Glutaminedependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity
-
KaadigeMR, Looper RE, Kamalanaadhan S, Ayer DE. Glutaminedependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity. Proc Natl Acad Sci USA 2009;106:14878-14883.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14878-14883
-
-
Kaadige, M.R.1
Looper, R.E.2
Kamalanaadhan, S.3
Ayer, D.E.4
-
6
-
-
64749116346
-
C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
-
Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T, Zeller KI, De Marzo AM, Van Eyk JE, Mendell JT, Dang CV. c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism.Nature 2009;458:762-765.
-
(2009)
Nature
, vol.458
, pp. 762-765
-
-
Gao, P.1
Tchernyshyov, I.2
Chang, T.C.3
Lee, Y.S.4
Kita, K.5
Ochi, T.6
Zeller, K.I.7
De Marzo, A.M.8
Van Eyk, J.E.9
Mendell, J.T.10
Dang, C.V.11
-
7
-
-
70350217425
-
Glioblastome cells require glutamate dehydrogenase to survive impairmentsof glucosemetabolismorAkt signaling
-
Yang C, Sudderth J, Dang T, Bachoo RM, McDonald JG, DeBerardinis RJ. Glioblastome cells require glutamate dehydrogenase to survive impairmentsof glucosemetabolismorAkt signaling.Cancer Res 2009;69:7986-7993.
-
(2009)
Cancer Res
, vol.69
, pp. 7986-7993
-
-
Yang, C.1
Sudderth, J.2
Dang, T.3
Bachoo, R.M.4
McDonald, J.G.5
Deberardinis, R.J.6
-
8
-
-
77957937428
-
Targeting mitochondrial glutaminase activity inhibits oncogenic transformation
-
Wang JB, Erickson JW, Fuji R, Ramachandran S,Gao P, Dinavahi R, Wilson KF, Ambrosio AL, Dias SM, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell 2010;18:207-219.
-
(2010)
Cancer Cell
, vol.18
, pp. 207-219
-
-
Wang, J.B.1
Erickson, J.W.2
Fuji, R.3
Ramachandran, S.4
Gao, P.5
Dinavahi, R.6
Wilson, K.F.7
Ambrosio, A.L.8
Dias, S.M.9
Dang, C.V.10
Cerione, R.A.11
-
9
-
-
77952212178
-
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
-
Hu W, Zhang C, Wu R, Sun Y, Levine A, Feng Z. Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function. Proc Natl Acad Sci USA 2010;107:7455-7460.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7455-7460
-
-
Hu, W.1
Zhang, C.2
Wu, R.3
Sun, Y.4
Levine, A.5
Feng, Z.6
-
10
-
-
84855453655
-
Glucoseindependent glutamine metabolism via TCA cycling for proliferation and survival in B cells
-
Le A, Lane AN, Hamaker M, Bose S, Gouw A, Barbi J, Tsukamoto T, Rojas CJ, Slusher BS, ZhangH, Zimmerman LJ, LieblerDC, Slebos RJ, Lorkiewicz PK, Higashi RM, Fan TW, Dang CV. Glucoseindependent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metab 2012;15:110-121.
-
(2012)
Cell Metab
, vol.15
, pp. 110-121
-
-
Le, A.1
Lane, A.N.2
Hamaker, M.3
Bose, S.4
Gouw, A.5
Barbi, J.6
Tsukamoto, T.7
Rojas, C.J.8
Slusher, B.S.9
Zhang, H.10
Zimmerman, L.J.11
Liebler, D.C.12
Slebos, R.J.13
Lorkiewicz, P.K.14
Higashi, R.M.15
Fan, T.W.16
Dang, C.V.17
-
11
-
-
78649276497
-
Energy metabolism of leukemia cells: Glycolysis versus oxidative phosphorylation
-
Suganuma K, Miwa H, Imai N, Shikami M, Gotou M, Goto M, Mizuno S, Takahashi M, Yamamoto H, Hiramatsu A, WakabayashiM, WataraiM,Hanamura I, Imamura A, MiharaH,Nitta M. Energy metabolism of leukemia cells: glycolysis versus oxidative phosphorylation. Leuk Lymphoma 2010;51:2112-2119.
-
(2010)
Leuk Lymphoma
, vol.51
, pp. 2112-2119
-
-
Suganuma, K.1
Miwa, H.2
Imai, N.3
Shikami, M.4
Gotou, M.5
Goto, M.6
Mizuno, S.7
Takahashi, M.8
Yamamoto, H.9
Hiramatsu, A.10
Wakabayashi, M.11
Watarai, M.12
Hanamura, I.13
Imamura, A.14
Mihara, H.15
Nitta, M.16
-
12
-
-
84876267967
-
Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose
-
Miwa H, Shikami M, Goto M, Mizuno S, Takahashi M, Tsunekawa-Imai N, Ishikawa T, Mizutani M, Horio T, Gotou M, Yamamoto H,WakabayashiM,WataraiM, Hanamura I, Imamura A, Mihara H, Nitta M. Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose. Oncol Rep 2013;29:2053-2057.
-
(2013)
Oncol Rep
, vol.29
, pp. 2053-2057
-
-
Miwa, H.1
Shikami, M.2
Goto, M.3
Mizuno, S.4
Takahashi, M.5
Tsunekawa-Imai, N.6
Ishikawa, T.7
Mizutani, M.8
Horio, T.9
Gotou, M.10
Yamamoto, H.11
Wakabayashi, M.12
Watarai, M.13
Hanamura, I.14
Imamura, A.15
Mihara, H.16
Nitta, M.17
-
13
-
-
84880945958
-
Growth of xenotransplanted leukemia cells is influenced by diet nutrients and is attenuated with 2-deoxyglucose
-
Tsunekawa-Imai N, Miwa H, ShikamiM, Suganuma K, GotoM, Mizuno S, Takahashi M, Mizutani M, Horio T, Komatsubara H, Gotou M, Yamamoto H, Wakabayashi M, Watarai M, Hanamura I, Imamura A, Mihara H, Nitta M. Growth of xenotransplanted leukemia cells is influenced by diet nutrients and is attenuated with 2-deoxyglucose. Leuk Res 2013;37:1132-1136.
-
(2013)
Leuk Res
, vol.37
, pp. 1132-1136
-
-
Tsunekawa-Imai, N.1
Miwa, H.2
Shikami, M.3
Suganuma, K.4
Goto, M.5
Mizuno, S.6
Takahashi, M.7
Mizutani, M.8
Horio, T.9
Komatsubara, H.10
Gotou, M.11
Yamamoto, H.12
Wakabayashi, M.13
Watarai, M.14
Hanamura, I.15
Imamura, A.16
Mihara, H.17
Nitta, M.18
-
14
-
-
0025269838
-
Metabolic basis for differential glutamine requirements of human leukemia cell lines
-
Kitoh T, Kubota M, Takimoto T, Hashimoto H, Shimizu T, Sano H, Akiyama Y, Mikawa H. Metabolic basis for differential glutamine requirements of human leukemia cell lines. J Cell Physiol 1990;143:150-153.
-
(1990)
J Cell Physiol
, vol.143
, pp. 150-153
-
-
Kitoh, T.1
Kubota, M.2
Takimoto, T.3
Hashimoto, H.4
Shimizu, T.5
Sano, H.6
Akiyama, Y.7
Mikawa, H.8
-
15
-
-
0034771851
-
Glutamine deprivationmediated cell shrinkage induces ligand-independent CD95 receptor signaling and apoptosis
-
Fumarola C, Zerbini A, Guidotti GG. Glutamine deprivationmediated cell shrinkage induces ligand-independent CD95 receptor signaling and apoptosis. Cell Death Differ 2001;8:1004-1013.
-
(2001)
Cell Death Differ
, vol.8
, pp. 1004-1013
-
-
Fumarola, C.1
Zerbini, A.2
Guidotti, G.G.3
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