Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12.like heterodimers extracellularly

Journal of Immunology

Volumn 192, Issue 12, 2014, Pages 6028-6036

  Abdi, Kaveh ^a   Singh, Nevil J ^b   Spooner, Eric ^c   Kessler, Benedikt M ^d   Radaev, Sergei ^e   Lantz, Larry ^a   Xiao, Tsan Sam ^a   Matzinger, Polly ^a   Sun, Peter D ^a   Ploegh, Hidde L ^c  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; CD5 ANTIGEN; HETERODIMER; INTERLEUKIN 12; INTERLEUKIN 12P35; INTERLEUKIN 12P40; MONOMER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOLOGICAL ACTIVITY; CHEMICAL ANALYSIS; CHO CELL LINE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN FUNCTION; PROTEOMICS;

ANIMALS; ANTIGENS, CD5; APOPTOSIS REGULATORY PROTEINS; DIMERIZATION; INTERLEUKIN-12; MICE; MICE, KNOCKOUT; PROTEOMICS; RECEPTORS, IMMUNOLOGIC;

EID: 84902205746     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400159     Document Type: Article

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