Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Rodrigues Sousa, Tiago ^a   Ladeirinha, Ana Filipa ^b   Santiago, Ana Raquel ^b   Carvalheiro, Helena ^a   Raposo, Bruno ^c   Alarcão, Ana ^b   Cabrita, António ^b   Holmdahl, Rikard ^c   Carvalho, Lina ^b   Souto Carneiro, M Margarida ^a  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRAN SULFATE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; LEUCINE RICH REPEAT KINASE 2; OXIDOREDUCTASE; PROTEIN NCF1; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; CYTOKINE; LRRK2 PROTEIN, MOUSE; NEUTROPHIL CYTOSOLIC FACTOR 1; PROTEIN SERINE THREONINE KINASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME PHOSPHORYLATION; INFLAMMATORY INFILTRATE; LEUKOCYTE; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; MONOCYTE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PLASMA CELL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; BLOOD; CHEMICALLY INDUCED; CHRONIC DISEASE; DISEASE MODEL; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY; PHENOTYPE; PHOSPHORYLATION;

ANIMALS; CHRONIC DISEASE; COLITIS; CYTOKINES; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; INFLAMMATION MEDIATORS; INTESTINAL MUCOSA; LEUKOCYTES; MALE; MICE; MICE, KNOCKOUT; MUTATION; NADPH OXIDASE; PHENOTYPE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES;

EID: 84902205044     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097532     Document Type: Article

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