The relationship between the metabolic syndrome and its components and bone status in postmenopausal women

Acta Physiologica Hungarica

Volumn 101, Issue 2, 2014, Pages 216-227

  Fodor, D ^a   Vesa, S ^a   Albu, A ^a   Simon, S ^a   Craciun, A ^a   Muntean, Laura ^a  

^a IULIU HATIEGANU UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

bone mineral density; bone turnover markers; metabolic syndrome; postmenopausal women; vitamin D

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; C REACTIVE PROTEIN; COLLAGEN TYPE 1; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; OSTEOCALCIN; VITAMIN D;

ADULT; ARTICLE; BODY MASS; BONE CHARACTERISTICS AND FUNCTIONS; BONE DENSITY; BONE MASS; BONE METABOLISM; BONE TURNOVER; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FRAGILITY FRACTURE; GLUCOSE BLOOD LEVEL; HIP; HUMAN; HYPERTENSION; ISCHEMIC HEART DISEASE; LUMBAR SPINE; MAJOR CLINICAL STUDY; METABOLIC SYNDROME X; POSTMENOPAUSE; PROTEIN BLOOD LEVEL; SPINE FRACTURE; VITAMIN BLOOD LEVEL; WAIST CIRCUMFERENCE;

BONE MINERAL DENSITY; BONE TURNOVER MARKERS; METABOLIC SYNDROME; POSTMENOPAUSAL WOMEN; VITAMIN D;

ABSORPTIOMETRY, PHOTON; AGE FACTORS; AGED; ALKALINE PHOSPHATASE; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; BONE DENSITY; BONE REMODELING; COLLAGEN TYPE I; CROSS-SECTIONAL STUDIES; FEMALE; FEMUR NECK; HUMANS; HYPERTENSION; LUMBAR VERTEBRAE; METABOLIC SYNDROME X; MIDDLE AGED; OSTEOCALCIN; PEPTIDES; POSTMENOPAUSE; VITAMIN D; WAIST CIRCUMFERENCE;

EID: 84902193490     PISSN: 0231424X     EISSN: 15882683     Source Type: Journal    
DOI: 10.1556/APhysiol.101.2014.2.10     Document Type: Article

References (44)

1. Guidelines for the management of arterial hypertension. The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur. Heart J. 28, 1462-1536 (2007)
2. Ahmed LA, Schirmer H, Berntsen GK, Fønnebø V, Joakimsen RM: Features of the metabolic syndrome and the risk of non-vertebral fractures: The Tromsø study. Osteoporos. Int. 17, 426-432 (2006)
3. Albala C, Yáñez M, Devoto E, Sostin C, Zeballos L, Santos JL: Obesity as a protective factor for postmenopausal osteoporosis. Int. J. Obes. Relat. Metab. Disord. 20, 1027-1032 (1996) (Pubitemid 26366457)
4. Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart JC, James WP, Loria CM, Smith SC Jr; International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; International Association for the Study of Obesity: Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute: American Heart Association; World Heart Federation: International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 120, 1640-1645 (2009)
5. Cappuccio FP, Meilahn E, Zmuda JM, Cauley JA: High blood pressure and bone-mineral loss in elderly white women: a prospective study. Study of Osteoporotic Fractures Research Group. Lancet 354, 971-975 (1999). (Pubitemid 29438401)
6. Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G: Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100, 197-207 (2000) (Pubitemid 30064908)
7. Farhat GN, Cauley JA: The link between osteoporosis and cardiovascular disease. Clin. Cases Miner. Bone Metab. 5, 19-34 (2008) (Pubitemid 351847127)
8. Felson DT, Zhang Y, Hannan MT, Anderson JJ: Effects of weight and body mass index in men and women: the Framingham study. J. Bone Miner. Res. 8, 567-573 (1993) (Pubitemid 23127916)
9. Fodor D, Bondor C, Albu A, Simon SP, Craciun A, Muntean L: The value of osteopontin in the assessment of bone mineral density status in postmenopausal women. J. Investig. Med. 61, 1521 (2013)
10. Genant HK, Wu CY, van Kuijk C, Nevitt MC: Vertebral fracture assessment using a semiquantitative technique. J. Bone Miner. Res. 8, 1137-1148 (1993) (Pubitemid 23261108)
11. Gradinaru D, Borsa C, Ionescu C, Margina D, Prada GI, Jansen E: Vitamin D status and oxidative stress markers in the elderly with impaired fasting glucose and type 2 diabetes mellitus. Aging Clin. Exp. Res. 24, 595-602 (2012)
12. Greco EA, Fornari R, Rossi F, Santiemma V, Prossomariti G, Annoscia C, Aversa A, Brama M, Marini M, Donini LM, Spera G, Lenzi A, Lubrano C, Migliaccio S: Is obesity protective for osteoporosis Evaluation of bone mineral density in individuals with high body mass index. Int. J. Clin. Pract. 64, 817-820 (2010)
13. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Costa F: American Heart Association; National Heart, Lung, and Blood Institute: Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112, 2735-2752 (2005) (Pubitemid 41532612)
14. Hanley DA, Brown JP, Tenenhouse A, Olszynski WP, Ioannidis G, Berger C, Prior JC, Pickard L, Murray TM, Anastassiades T, Kirkland S, Joyce C, Joseph L, Papaioannou A, Jackson SA, Poliquin S, Adachi JD: Canadian Multicentre Osteoporosis Study Research Group: Associations among disease conditions, bone mineral density, and prevalent vertebral deformities in men and women 50 years of age and older: cross-sectional results from the Canadian Multicentre Osteoporosis Study. J. Bone Miner. Res. 18, 784-790 (2003) (Pubitemid 36899328)
15. Hernández JL, Olmos JM, de Juan J, Martínez J, Ramos C, Valero C, Nan D, González-Macías J: Heel quantitative ultrasound parameters in subjects with metabolic syndrome: the Camargo Cohort Study. Maturitas 69, 162-167 (2011)
16. Hernández JL, Olmos JM, Pariente E, Martinez J, Valero C, Garcia-Velasco P, Nan D, Llorca J, Gonzales-Macias J: Metabolic syndrome and bone metabolism: the Camargo Cohort study. Menopause 17, 955-961 (2010)
17. Hwang DK, Choi HJ: The relationship between low bone mass and metabolic syndrome in Korean women. Osteoporos. Int. 21, 425-431 (2010)
18. Jeon YK, Lee JG, Kim SS, Kim BH, Kim SJ, Kim YK, Kim IJ: Association between bone mineral density and metabolic syndrome in pre-and postmenopausal women. Endocr. J. 58, 8793 (2011)
19. Kim HY, Choe JW, Kim HK, Bae SJ, Kim BJ, Lee SH, Koh JM, Han KO, Park HM, Kim GS: Negative association between metabolic syndrome and bone mineral density in Koreans, especially in men. Calcif. Tissue Int. 86, 350-358 (2010)
20. Kim KC, Shin DH, Lee SY, Im JA, Lee DC: Relation between obesity and bone mineral density and vertebral fractures in Korean postmenopausal women. Yonsei Med. J. 51, 857-863 (2010)
21. Kinjo M, Setoguchi S, Solomon DH: Bone mineral density in adults with metabolic syndrome: analysis in a population-based U.S. sample. J. Clin. Endocrinol. Metab. 92, 4161-4164 (2007) (Pubitemid 350074726)
22. Lee WY, Park JS, Noh SY, Rhee EJ, Sung KC, Kim BS, Kang JH, Kim SW, Lee MH, Park JR: C-reactive protein concentrations are related to insulin resistance and metabolic syndrome as defined by the ATP III report. Int. J. Cardiol. 97, 101-106 (2004)
23. Lidfeldt J, Holmdahl L, Samsioe G, Nerbrand C, Nyberg P, Scherstén B, Agardh CD: The influence of hormonal status and features of the metabolic syndrome on bone density: a population-based study of Swedish women aged 50 to 59 years. The women's health in the Lund area study. Metabolism 51, 267-270 (2002) (Pubitemid 34168244)
24. Matei C, Pop I, Jurcut R, Suceveanu M, Predescu D, Nechita E, Ionescu P, Ciovica D, Ginghina C: Romanian multicentric study of the prevalence of metabolic syndrome-ROMES. Hellenic J. Cardiol. 49, 303-309 (2008)
25. Migliaccio S, Greco EA, Fornari R, Donini LM, Lenzi A: Is obesity in women protective against osteoporosis Diabetes Metab. Syndr. Obes. 4, 273-282 (2011)
26. Oda E, Kawai R: Comparison between high-sensitivity C-reactive protein (hs-CRP) and white blood cell count (WBC) as an inflammatory component of metabolic syndrome in Japanese. Intern. Med. 49, 117-124 (2010)
27. Orwoll ES, Bevan L, Phipps KR: Determinants of bone mineral density in older men. Osteoporos. Int. 11, 815-821 (2000) (Pubitemid 32049470)
28. Park KK, Kim SJ, Moon ES: Association between bone mineral density and metabolic syndrome in postmenoupausal Korean Women. Gynecol. Obstet. Invest. 69, 145-152 (2010)
29. Pitsavos C: The prevalence of the metabolic syndrome is high in Balkan countries. Hellenic J. Cardiol. 49, 310-311 (2008)
30. Porojnicu AC, Moroti-Constantinescu R, Laslau A, Lagunova Z, Dahlback A, Hristea A, Moan J: Vitamin D status in healthy Romanian caregivers and risk of respiratory infections. Public Health Nutr. 15, 2157-2162 (2012)
31. Ridker PM, Wilson PWF, Grandy SM: Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk Circulation 109, 2818-2825 (2004) (Pubitemid 38780294)
32. Riggs BL, Melton Iii LJ 3rd, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S: Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J. Bone Miner. Res. 19, 1945-1954 (2004) (Pubitemid 41103408)
33. Skerry TM, Suva LJ: Investigation of the regulation of bone mass by mechanical loading: from quantitative cytochemistry to gene array. Cell Biochem. Funct. 21, 223-229 (2003) (Pubitemid 36988375)
34. Szulc P, Varennes A, Delmas PD, Goudable J, Chapurlat R: Men with metabolic syndrome have lower bone mineral density but lower fracture risk-The MINOS study. J. Bone Miner. Res. 25, 1446-1454 (2010)
35. Tseng YH, Huang KC, Lui ML, Shu WT, Sheu WH: Association between metabolic syndrome (MS) and bone mineral loss: a cross-sectional study in Puli Township in Taiwan. Arch. Gerontol. Geriatr. 49 Suppl 2, S37-S40 (2009)
36. von Muhlen D, Safii S, Jassal SK, Svartberg J, Barrett-Connor E: Associations between the metabolic syndrome and bone health in older men and women: the Rancho Bernado Study. Osteoporos. Int. 18, 1337-1344 (2007) (Pubitemid 47389466)
37. Woo J, Kwok T, Leung J, Tang N: Dietary intake, blood pressure and osteoporosis. J. Hum. Hypertens. 23, 451-455 (2009)
38. World Health Organization Department of Non-Communicable Disease Surveillance. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications (1999)
39. Xu S, Yu JJ: Beneath the minerals, a layer of round lipid particles was identified to mediate collagen calcification in compact bone formation. Biophys. J. 91, 4221-4229 (2006) (Pubitemid 44887280)
40. Xue P, Gao P, Li Y: The association between metabolic syndrome and bone mineral density: a meta-analysis. Endocrine 42, 546-554 (2012)
41. Yamaguchi T, Kanazawa I, Yamamoto M, Kurioka S, Yamauchi M, Yano S, Sugimoto T: Associations between components of the metabolic syndrome versus bone mineral density and vertebral fractures in patients with type 2 diabetes. Bone 45, 174-179 (2009)
42. Yeap BB, Chubb SA, Flicker L, McCaul KA, Ebeling PR, Beilby JP, Norman PE: Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels. Eur. J. Endocrinol. 163, 265-272 (2010)
43. Yoldemir T, Erenus M: The impact of metabolic syndrome on bone mineral density in postmenopausal women. Gynecol. Endocrinol. 28, 391-395 (2012)
44. Zhao LJ, Liu YJ, Liu PY, Hamilton J, Recker RR, Deng HW: Relationship of obesity with osteoporosis. J. Clin. Endocrinol. Metab. 92, 1640-1646 (2007) (Pubitemid 46997165)