The association between metabolic syndrome and bone mineral density: A meta-analysis

Endocrine

Volumn 42, Issue 3, 2012, Pages 546-554

  Xue, Peng ^a   Gao, Ping ^a   Li, Yukun ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

Bone mineral density; Meta analysis; Metabolic syndrome; Osteoporosis

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; TRIACYLGLYCEROL;

ARTICLE; BONE DENSITOMETER; BONE DENSITY; CAUCASIAN; DISEASE ASSOCIATION; DUAL ENERGY X RAY ABSORPTIOMETRY; DYSLIPIDEMIA; FEMUR NECK; HUMAN; HYPERTENSION; INFORMATION PROCESSING; INSULIN RESISTANCE; METABOLIC SYNDROME X; OBESITY; OSTEOPENIA; OSTEOPOROSIS; PRIORITY JOURNAL; SPINE; SYSTEMATIC REVIEW; ADULT; FEMALE; MALE; META ANALYSIS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHOTON ABSORPTIOMETRY; PHYSIOLOGY; PUBLISHING; REVIEW; STATISTICAL ANALYSIS;

ABSORPTIOMETRY, PHOTON; ADULT; BONE DENSITY; DATA INTERPRETATION, STATISTICAL; FEMALE; HUMANS; MALE; METABOLIC SYNDROME X; OSTEOPOROSIS; PUBLICATION BIAS; SPINE;

EID: 84878258755     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-012-9684-1     Document Type: Article

References (61)

1. NIH Consensus Development Panel on Osteoporosis Prevention, Diagnosis, and Therapy, Osteoporosis prevention, diagnosis, and therapy. JAMA 285(6), 785-795 (2001)
2. Writing Group for the ISCD Position Development Conference, Diagnosis of osteoporosis in men, premenopausal women, and children. J. Clin. Densitom. 7(1), 17-26 (2004)
3. J.Y. Reginster, P. Gillet, W. Ben Sedrine, G. Brands, O. Ethgen, C. de Froidmont, C. Gosset, Direct costs of hip fractures in patients over 60 years of age in Belgium. Pharmacoeconomics 15(5), 507-514 (1999)
4. C. Gazzaruso, An increased risk for fractures: another cause of frailty in HIV-infected subjects. Endocrine (2012). doi: 10.1007/s12020-012-9640-0
5. M.A. Cornier, D. Dabelea, T.L. Hernandez, R.C. Lindstrom, A.J. Steig, N.R. Stob, R.E. Van Pelt, H. Wang, R.H. Eckel, The metabolic syndrome. Endocr. Rev. 29(7), 777-822 (2008). doi: 10.1210/er.2008-0024
6. A.S. Gami, B.J. Witt, D.E. Howard, P.J. Erwin, L.A. Gami, V.K. Somers, V.M. Montori, Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies. J. Am. Coll. Cardiol. 49(4), 403-414 (2007). doi: 10.1016/j.jacc.2006.09.032
7. E.S. Ford, C. Li, N. Sattar, Metabolic syndrome and incident diabetes: current state of the evidence. Diabetes Care 31(9), 1898-1904 (2008). doi: 10.2337/dc08-0423
8. L.R. Nelson, S.E. Bulun, Estrogen production and action. J. Am. Acad. Dermatol. 45(3 Suppl), S116-S124 (2001)
9. H. Ohta, T. Ikeda, T. Masuzawa, K. Makita, Y. Suda, S. Nozawa, Differences in axial bone mineral density, serum levels of sex steroids, and bone metabolism between postmenopausal and age- and body size-matched premenopausal subjects. Bone 14(2), 111-116 (1993)
10. L.C. Hofbauer, M. Schoppet, Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA 292(4), 490-495 (2004). doi: 10.1001/jama.292.4.490
11. B.J. Smith, M.R. Lerner, S.Y. Bu, E.A. Lucas, J.S. Hanas, S.A. Lightfoot, R.G. Postier, M.S. Bronze, D.J. Brackett, Systemic bone loss and induction of coronary vessel disease in a rat model of chronic inflammation. Bone 38(3), 378-386 (2006). doi: 10.1016/j.bone.2005.09.008
12. R.M. Campos, A. de Piano, P.L. da Silva, J. Carnier, P.L. Sanches, F.C. Corgosinho, D.C. Masquio, M. Lazaretti-Castro, L.M. Oyama, C.M. Nascimento, L. Tock, M.T. de Mello, S. Tufik, A.R. Damaso, The role of pro/anti-inflammatory adipokines on bone metabolism in NAFLD obese adolescents: effects of long-term interdisciplinary therapy. Endocrine (2012). doi: 10.1007/s12020-012-9613-3
13. S. Cvijetic, M. Pavlovic, D. Pasalic, S. Dodig, Ultrasound bone measurement in an older population with metabolic syndrome. Aging Clin Exp Res 23(1), 29-34 (2011)
14. D.N. Binici, N. Gunes, Risk factors leading to reduced bone mineral density in hemodialysis patients with metabolic syndrome. Ren. Fail. 32(4), 469-474 (2010). doi: 10.3109/08860221003675260
15. M. Kinjo, S. Setoguchi, D.H. Solomon, Bone mineral density in adults with the metabolic syndrome: analysis in a population-based U.S. sample. J. Clin. Endocrinol. Metab. 92(11), 4161-4164 (2007). doi: 10.1210/jc.2007-0757
16. Y.H. Tseng, K.C. Huang, M.L. Liu, W.T. Shu, W.H. Sheu, Association between metabolic syndrome (MS) and bone mineral loss: a cross-sectional study in Puli Township in Taiwan. Arch. Gerontol. Geriatr. 49(Suppl 2), S37-S40 (2009). doi: 10.1016/S0167-4943(09)70011-1
17. T. Yamaguchi, I. Kanazawa, M. Yamamoto, S. Kurioka, M. Yamauchi, S. Yano, T. Sugimoto, Associations between components of the metabolic syndrome versus bone mineral density and vertebral fractures in patients with type 2 diabetes. Bone 45(2), 174-179 (2009). doi: 10.1016/j.bone.2009.05.003
18. L.A. Ahmed, H. Schirmer, G.K. Berntsen, V. Fonnebo, R.M. Joakimsen, Features of the metabolic syndrome and the risk of non-vertebral fractures: the Tromso study. Osteoporos. Int. 17(3), 426-432 (2006). doi: 10.1007/s00198-005- 0003-z
19. G. Iacobellis, M. Iorio, N. Napoli, D. Cotesta, L. Zinnamosca, C. Marinelli, L. Petramala, S. Minisola, E. D'Erasmo, C. Letizia, Relation of adiponectin, visfatin and bone mineral density in patients with metabolic syndrome. J. Endocrinol. Investig. 34(1), e12-e15 (2011). doi: 10.3275/7170
20. H.T. Lee, J. Shin, Y.H. Lim, B.K. Kim, Y.T. Kim, J.U. Lee, S. Hong, S.Y. Song, S.H. Cho, The relationship between coronary artery calcification and bone mineral density in patients according to their metabolic syndrome status. Korean Circ. J. 41(2), 76-82 (2011). doi: 10.4070/kcj.2011.41.2.76
21. L.J. Lu, F. Nayeem, K.E. Anderson, J.J. Grady, M. Nagamani, Lean body mass, not estrogen or progesterone, predicts peak bone mineral density in premenopausal women. J. Nutr. 139(2), 250-256 (2009). doi: 10.3945/jn.108.098954
22. J. Lidfeldt, L. Holmdahl, G. Samsioe, C. Nerbrand, P. Nyberg, B. Schersten, C.D. Agardh, The influence of hormonal status and features of the metabolic syndrome on bone density: a population-based study of Swedish women aged 50 to 59 years. The women's health in the Lund area study. Metabolism 51(2), 267-270 (2002)
23. Y.K. Jeon, J.G. Lee, S.S. Kim, B.H. Kim, S.J. Kim, Y.K. Kim, I.J. Kim, Association between bone mineral density and metabolic syndrome in pre- and postmenopausal women. Endocr. J. 58(2), 87-93 (2011)
24. P. Szulc, A. Varennes, P.D. Delmas, J. Goudable, R. Chapurlat, Men with metabolic syndrome have lower bone mineral density but lower fracture risk - the MINOS study. J. Bone Miner. Res. 25(6), 1446-1454 (2010). doi: 10.1002/jbmr.13
25. K.K. Park, S.J. Kim, E.S. Moon, Association between bone mineral density and metabolic syndrome in postmenopausal Korean women. Gynecol. Obstet. Investig. 69(3), 145-152 (2010). doi: 10.1159/000264665
26. D. von Muhlen, S. Safii, S.K. Jassal, J. Svartberg, E. Barrett-Connor, Associations between the metabolic syndrome and bone health in older men and women: the Rancho Bernardo study. Osteoporos. Int. 18(10), 1337-1344 (2007). doi: 10.1007/s00198-007-0385-1
27. D.K. Hwang, H.J. Choi, The relationship between low bone mass and metabolic syndrome in Korean women. Osteoporos. Int. 21(3), 425-431 (2010). doi: 10.1007/s00198-009-0990-2
28. M. Boyanov, D. Bakalov, Z. Boneva, Bone mineral density in men with and without the metabolic syndrome. Aging Male 12(2-3), 62-65 (2009). doi: 10.1080/13685530903150812
29. J.L. Hernandez, J.M. Olmos, E. Pariente, J. Martinez, C. Valero, P. Garcia-Velasco, D. Nan, J. Llorca, J. Gonzalez-Macias, Metabolic syndrome and bone metabolism: the Camargo Cohort study. Menopause 17(5), 955-961 (2010). doi: 10.1097/gme.0b013e3181e39a15
30. S. Yaturu, S. Humphrey, C. Landry, S.K. Jain, Decreased bone mineral density in men with metabolic syndrome alone and with type 2 diabetes. Med. Sci. Monit. 15(1), CR5-CR9 (2009)
31. H.Y. Kim, J.W. Choe, H.K. Kim, S.J. Bae, B.J. Kim, S.H. Lee, J.M. Koh, K.O. Han, H.M. Park, G.S. Kim, Negative association between metabolic syndrome and bone mineral density in Koreans, especially in men. Calcif. Tissue Int. 86(5), 350-358 (2010). doi: 10.1007/s00223-010-9347-2
32. Y.-J. Zhang, W. Zhao, H. Zhang, X.-M. Wu, L.-J. Jiang, X.-C. Song, M. Li, Effect of metabolic syndrome on bone mineral density of male patients with type 2 diabetes. TianJin Med. J. 38(3), 230-232 (2010)
33. Y.-J. Zhang, W. Zhao, H. Zhang, J. Liu, X.-Q. Chen, S.-S. Cui, L. Zhang, Analysis of the related factors of bone mineral density in female patients with type 2 diabetes complicated metabolic syndrome. Chin. J. Prev. Control Chronic Dis. 18(05), 481-482 (2010)
34. D.T. Felson, Y. Zhang, M.T. Hannan, J.J. Anderson, Effects of weight and body mass index on bone mineral density in men and women: the Framingham study. J. Bone Miner. Res. 8(5), 567-573 (1993). doi: 10.1002/jbmr.5650080507
35. R. Marcus, G. Greendale, B.A. Blunt, T.L. Bush, S. Sherman, R. Sherwin, H. Wahner, B. Wells, Correlates of bone mineral density in the postmenopausal estrogen/progestin interventions trial. J. Bone Miner. Res. 9(9), 1467-1476 (1994). doi: 10.1002/jbmr.5650090920
36. C. De Laet, J.A. Kanis, A. Oden, H. Johanson, O. Johnell, P. Delmas, J.A. Eisman, H. Kroger, S. Fujiwara, P. Garnero, E.V. McCloskey, D. Mellstrom, L.J. Melton III, P.J. Meunier, H.A. Pols, J. Reeve, A. Silman, A. Tenenhouse, Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos. Int. 16(11), 1330-1338 (2005). doi: 10.1007/s00198-005-1863-y
37. J.M. Gimble, M.E. Nuttall, Bone and fat: old questions, new insights. Endocrine 23(2-3), 183-188 (2004). doi: 10.1385/ENDO:23:2-3:183
38. S.L. Edelstein, E. Barrett-Connor, Relation between body size and bone mineral density in elderly men and women. Am. J. Epidemiol. 138(3), 160-169 (1993)
39. E.A. Jankowska, E. Rogucka, M. Medras, Are general obesity and visceral adiposity in men linked to reduced bone mineral content resulting from normal ageing? A population-based study. Andrologia 33(6), 384-389 (2001)
40. R. Blaauw, E.C. Albertse, S. Hough, Body fat distribution as a risk factor for osteoporosis. S. Afr. Med. J. 86(9), 1081-1084 (1996)
41. C. Torti, G. Mazziotti, P.A. Soldini, E. Foca, R. Maroldi, D. Gotti, G. Carosi, A. Giustina, High prevalence of radiological vertebral fractures in HIV-infected males. Endocrine (2011). doi: 10.1007/s12020-011-9586-7
42. S.S. Moon, Y.S. Lee, S.W. Kim, Association of nonalcoholic fatty liver disease with low bone mass in postmenopausal women. Endocrine (2012). doi: 10.1007/s12020-012-9639-6
43. A.H. Holmberg, P.M. Nilsson, J.A. Nilsson, K. Akesson, The association between hyperglycemia and fracture risk in middle age. A prospective, population-based study of 22,444 men and 10,902 women. J. Clin. Endocrinol. Metab. 93(3), 815-822 (2008). doi: 10.1210/jc.2007-0843
44. I. Kanazawa, T. Yamaguchi, M. Yamamoto, M. Yamauchi, S. Yano, T. Sugimoto, Combination of obesity with hyperglycemia is a risk factor for the presence of vertebral fractures in type 2 diabetic men. Calcif. Tissue Int. 83(5), 324-331 (2008). doi: 10.1007/s00223-008-9178-6
45. K. Agbaht, A. Gurlek, J. Karakaya, M. Bayraktar, Circulating adiponectin represents a biomarker of the association between adiposity and bone mineral density. Endocrine 35(3), 371-379 (2009). doi: 10.1007/s12020-009-9158-2
46. G. Mazziotti, M. Gola, A. Bianchi, T. Porcelli, A. Giampietro, V. Cimino, M. Doga, C. Gazzaruso, L. De Marinis, A. Giustina, Influence of diabetes mellitus on vertebral fractures in men with acromegaly. Endocrine 40(1), 102-108 (2011). doi: 10.1007/s12020-011-9486-x
47. D.E. Grobbee, W.H. Hackeng, J.C. Birkenhager, A. Hofman, Raised plasma intact parathyroid hormone concentrations in young people with mildly raised blood pressure. Br. Med. J. (Clin. Res. Ed.) 296(6625), 814-816 (1988)
48. G.S. Hughes Jr, M.J. Oexmann, H.S. Margolius, S. Epstein, N.H. Bell, Normal vitamin D and mineral metabolism in essential hypertension. Am. J. Med. Sci. 296(4), 252-259 (1988)
49. D.A. Hanley, J.P. Brown, A. Tenenhouse, W.P. Olszynski, G. Ioannidis, C. Berger, J.C. Prior, L. Pickard, T.M. Murray, T. Anastassiades, S. Kirkland, C. Joyce, L. Joseph, A. Papaioannou, S.A. Jackson, S. Poliquin, J.D. Adachi, Associations among disease conditions, bone mineral density, and prevalent vertebral deformities in men and women 50 years of age and older: cross-sectional results from the Canadian Multicentre Osteoporosis Study. J. Bone Miner. Res. 18(4), 784-790 (2003). doi: 10.1359/jbmr.2003.18.4.784
50. M.E. Mussolino, R.F. Gillum, Bone mineral density and hypertension prevalence in postmenopausal women: results from the Third National Health and Nutrition Examination Survey. Ann. Epidemiol. 16(5), 395-399 (2006). doi: 10.1016/j.annepidem.2005.06.051
51. S. Xu, J.J. Yu, Beneath the minerals, a layer of round lipid particles was identified to mediate collagen calcification in compact bone formation. Biophys. J. 91(11), 4221-4229 (2006). doi: 10.1529/biophysj.105.075804
52. S. Adami, V. Braga, M. Zamboni, D. Gatti, M. Rossini, J. Bakri, E. Battaglia, Relationship between lipids and bone mass in 2 cohorts of healthy women and men. Calcif. Tissue Int. 74(2), 136-142 (2004). doi: 10.1007/s00223-003-0050-4
53. T. Yamaguchi, T. Sugimoto, S. Yano, M. Yamauchi, H. Sowa, Q. Chen, K. Chihara, Plasma lipids and osteoporosis in postmenopausal women. Endocr. J. 49(2), 211-217 (2002)
54. E.M. Dennison, H.E. Syddall, A. Aihie Sayer, H.J. Martin, C. Cooper, Lipid profile, obesity and bone mineral density: the Hertfordshire Cohort study. QJM 100(5), 297-303 (2007). doi: 10.1093/qjmed/hcm023
55. W.Y. Fujimoto, Overview of non-insulin-dependent diabetes mellitus (NIDDM) in different population groups. Diabet. Med. 13(9 Suppl 6), S7-S10 (1996)
56. N. Abate, M. Chandalia, The impact of ethnicity on type 2 diabetes. J. Diabetes Complicat. 17(1), 39-58 (2003)
57. N.A. Pocock, K.A. Noakes, M. Griffiths, N. Bhalerao, P.N. Sambrook, J.A. Eisman, J. Freund, A comparison of longitudinal measurements in the spine and proximal femur using lunar and hologic instruments. J. Bone Miner. Res. 12(12), 2113-2118 (1997). doi: 10.1359/jbmr.1997.12.12.2113
58. J. Makovey, V. Naganathan, P. Sambrook, Gender differences in relationships between body composition components, their distribution and bone mineral density: a cross-sectional opposite sex twin study. Osteoporos. Int. 16(12), 1495-1505 (2005). doi: 10.1007/s00198-005-1841-4
59. G. Mazziotti, J. Bilezikian, E. Canalis, D. Cocchi, A. Giustina, New understanding and treatments for osteoporosis. Endocrine 41(1), 58-69 (2012). doi: 10.1007/s12020-011-9570-2
60. Y. Hamada, S. Kitazawa, R. Kitazawa, K. Kono, S. Goto, H. Komaba, H. Fujii, Y. Yamamoto, H. Yamamoto, M. Usami, M. Fukagawa, The effects of the receptor for advanced glycation end products (RAGE) on bone metabolism under physiological and diabetic conditions. Endocrine 38(3), 369-376 (2010). doi: 10.1007/s12020-010-9390-9
61. J.A. Pasco, M.J. Henry, S. Korn, G.C. Nicholson, M.A. Kotowicz, The metabolic syndrome and bone mineral density in a random sample of Australian men. JMHG. 4(3), 298-299 (2007)