Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos

Aquatic Toxicology

Volumn 154, Issue , 2014, Pages 221-229

  Fetter, Eva ^a   Krauss, Martin ^a   Brion, François ^b   Kah, Olivier ^c   Scholz, Stefan ^a   Brack, Werner ^a  

^a HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^b INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Animal alternatives; Aromatase; Danio rerio; Endocrine disruptors; Environmental xenoestrogens; Fractionation

Indexed keywords

ALKYLPHENOL; ENVIRONMENTAL CHEMICAL; ESTRONE; UNCLASSIFIED DRUG; XENOESTROGEN;

CHEMICAL ANALYSIS; CONCENTRATION (COMPOSITION); EMBRYO; ENDOCRINE DISRUPTOR; ESTROGENIC COMPOUND; FISH; FLUVIAL DEPOSIT; FRACTIONATION; PHENOL; SUSPENDED PARTICULATE MATTER;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EFFECT DIRECTED ANALYSIS; EMBRYO; ESTROGEN ACTIVITY; ESTROGEN RESPONSIVE ELEMENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEDIMENT; TRANSGENIC ZEBRAFISH;

ANIMAL ALTERNATIVES; AROMATASE; DANIO RERIO; ENDOCRINE DISRUPTORS; ENVIRONMENTAL XENOESTROGENS; FRACTIONATION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; AROMATASE; BIOLOGICAL ASSAY; EMBRYO, NONMAMMALIAN; ENVIRONMENTAL MONITORING; ESTROGENS; ESTRONE; GENE EXPRESSION REGULATION; GEOLOGIC SEDIMENTS; GREEN FLUORESCENT PROTEINS; RIVERS; WATER POLLUTANTS, CHEMICAL; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84902148709     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2014.05.016     Document Type: Article

References (57)

1. Ali S., van Mil H.G., Richardson M.K. Large-scale assessment of the zebrafish embryo as a possible predictive model in toxicity testing. PLoS ONE 2011, 6:e21076.
2. Andrási N., Helenkár A., Záray G., Vasanits A., Molnár-Perl I. Derivatization and fragmentation pattern analysis of natural and synthetic steroids, as their trimethylsilyl (oxime) ether derivatives by gas chromatography mass spectrometry: analysis of dissolved steroids in wastewater samples. J. Chromatogr. A 2011, 1218:1878-1890.
3. Blair R.M., Fang H., Branham W.S., Hass B.S., Dial S.L., Moland C.L., Tong W., Shi L., Perkins R., Sheehan D.M. The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands. Toxicol. Sci. 2000, 54:138-153.
4. Brack W. Effect-directed analysis: a promising tool for the identification of organic toxicants in complex mixtures?. Anal. Bioanal. Chem. 2003, 377:397-407.
5. Brion F., Le Page Y., Piccini B., Cardoso O., Tong S.K., Chung B.C., Kah O. Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos. PLoS ONE 2012, 7:e36069.
6. Chen H., Hu J., Yang J., Wang Y., Xu H., Jiang Q., Gong Y., Gu Y., Song H. Generation of a fluorescent transgenic zebrafish for detection of environmental estrogens. Aquat. Toxicol. 2010, 96:53-61.
7. Clements R.G., Nabholz J.V. ECOSAR: a computer program and user's guide for estimating the ecotoxicity of industrial chemicals based on structure activity relationships, EPA-748-R-93-002 1994, U.S. Environmental Protection Agency, Office of Pollution Prevention and Toxics 7403., Washington, DC.
8. Colborn T., vom Saal F.S., Soto A.M. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ. Health Perspect. 1993, 101:378-384.
9. Creusot N., Ait-Aissa S., Tapie N., Pardon P., Brion F., Sanchez W., Thybaud E., Porcher J.M., Budzinski H. Identification of synthetic steroids in river water downstream from pharmaceutical manufacture discharges based on a bioanalytical approach and passive sampling. Environ. Sci. Technol. 2014, 48:3649-3657.
10. Creusot N., Budzinski H., Balaguer P., Kinani S., Porcher J.M., Ait-Aissa S. Effect-directed analysis of endocrine-disrupting compounds in multi-contaminated sediment: identification of novel ligands of estrogen and pregnane X receptors. Anal. Bioanal. Chem. 2013, 405:2553-2566.
11. EPA Sample Clean-up with GPC, 3640 1994, United States Environmental Protection Agency, United States.
12. Frische T., Faust M., Meyer W., Backhaus T. Toxic masking and synergistic modulation of the estrogenic activity of chemical mixtures in a yeast estrogen screen (YES). Environ. Sci. Pollut. Res. Int. 2009, 16:593-603.
13. Frye C.A., Bo E., Calamandrei G., Calza L., Dessi-Fulgheri F., Fernandez M., Fusani L., Kah O., Kajta M., Le Page Y., Patisaul H.B., Venerosi A., Wojtowicz A.K., Panzica G.C. Endocrine disrupters: a review of some sources, effects, and mechanisms of actions on behaviour and neuroendocrine systems. J. Neuroendocrinol. 2012, 24:144-159.
14. Gabriel F.L., Routledge E.J., Heidlberger A., Rentsch D., Guenther K., Giger W., Sumpter J.P., Kohler H.P. Isomer-specific degradation and endocrine disrupting activity of nonylphenols. Environ. Sci. Technol. 2008, 42:6399-6408.
15. Grund S., Higley E., Schonenberger R., Suter M.J., Giesy J.P., Braunbeck T., Hecker M., Hollert H. The endocrine disrupting potential of sediments from the Upper Danube River (Germany) as revealed by in vitro bioassays and chemical analysis. Environ. Sci. Pollut. Res. Int. 2011, 18:446-460.
16. Hollert H., Durr M., Holtey-Weber R., Islinger M., Brack W., Farber H., Erdinger L., Braunbeck T. Endocrine disruption of water and sediment extracts in a non-radioactive dot blot/RNAse protection-assay using isolated hepatocytes of rainbow trout. Environ. Sci. Pollut. Res. Int. 2005, 12:347-360.
17. Ji C., Jin X., He J., Yin Z. Use of TSHbeta:EGFP transgenic zebrafish as a rapid in vivo model for assessing thyroid-disrupting chemicals. Toxicol. Appl. Pharmacol. 2012, 262:149-155.
18. Jung E.M., An B.S., Yang H., Choi K.C., Jeung E.B. Biomarker genes for detecting estrogenic activity of endocrine disruptors via estrogen receptors. Int. J. Environ. Res. Publ. Health 2012, 9:698-711.
19. Jurajda P., Adamek Z., Janac M., Valova Z. Longitudinal patterns in fish and macrozoobenthos assemblages reflect degradation of water quality and physical habitat in the Bilina river basin. Czech J. Anim. Sci. 2010, 55:123-136.
20. Kidd K.A., Blanchfield P.J., Mills K.H., Palace V.P., Evans R.E., Lazorchak J.M., Flick R.W. Collapse of a fish population after exposure to a synthetic estrogen. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:8897-8901.
21. Knöbel M., Busser F.J., Rico-Rico A., Kramer N.I., Hermens J.L., Hafner C., Tanneberger K., Schirmer K., Scholz S. Predicting adult fish acute lethality with the zebrafish embryo: relevance of test duration, endpoints, compound properties, and exposure concentration analysis. Environ. Sci. Technol. 2012, 46:9690-9700.
22. Le Page Y., Menuet A., Kah O., Pakdel F. Characterization of a cis-acting element involved in cell-specific expression of the zebrafish brain aromatase gene. Mol. Reprod. Dev. 2008, 75:1549-1557.
23. Legler J., Broekhof J.L.M., Brouwer A., Lanser P.H., Murk A.J., Van der Saag P.T., Vethaak A.D., Wester P., Zivkovic D., Van der Burg B. A novel in vivo bioassay for (xeno-)estrogens using transgenic zebrafish. Environ. Sci. Technol. 2000, 34:4439-4444.
24. Legler J., van Velzen M., Cenijn P.H., Houtman C.J., Lamoree M.H., Wegener J.W. Effect-directed analysis of municipal landfill soil reveals novel developmental toxicants in the zebrafish Danio rerio. Environ. Sci. Technol. 2011, 45:8552-8558.
25. Li J., Gramatica P. QSAR classification of estrogen receptor binders and pre-screening of potential pleiotropic EDCs. SAR QSAR Environ. Res. 2010, 21:657-669.
26. LMC OECD QSAR Application Toolbox V3.0 2012, Available from http://www.qsartoolbox.org.
27. Maes J., Verlooy L., Buenafe O.E., de Witte P.A., Esguerra C.V., Crawford A.D. Evaluation of 14 organic solvents and carriers for screening applications in zebrafish embryos and larvae. PLoS ONE 2012, 7:e43850.
28. Maffini M.V., Rubin B.S., Sonnenschein C., Soto A.M. Endocrine disruptors and reproductive health: the case of bisphenol-A. Mol. Cell. Endocrinol. 2006, 254-255:179-186.
29. Marvin C., Coakley J., Mayer T., Brown M., Thiessen L. Application of faecal sterol ratios in sediments and effluents as source tracers. Water Qual. Res. J. Canada 2001, 36:781-792.
30. Menuet A., Pellegrini E., Brion F., Gueguen M.M., Anglade I., Pakdel F., Kah O. Expression and estrogen-dependent regulation of the zebrafish brain aromatase gene. J. Comp. Neurol. 2005, 485:304-320.
31. Mombelli E. Evaluation of the OECD (Q)SAR Application Toolbox for the profiling of estrogen receptor binding affinities. SAR QSAR Environ. Res. 2012, 23:37-57.
32. Mouriec K., Gueguen M.M., Manuel C., Percevault F., Thieulant M.L., Pakdel F., Kah O. Androgens upregulate cyp19a1b (aromatase B) gene expression in the brain of zebrafish (Danio rerio) through estrogen receptors. Biol. Reprod. 2009, 80:889-896.
33. Nagel R. DarT: the embryo test with the Zebrafish Danio rerio - a general model in ecotoxicology and toxicology. ALTEX 2002, 19(Suppl. 1):38-48.
34. Nakada N., Tanishima T., Shinohara H., Kiri K., Takada H. Pharmaceutical chemicals and endocrine disrupters in municipal wastewater in Tokyo and their removal during activated sludge treatment. Water Res. 2006, 40:3297-3303.
35. Oecd Fish Short Term Reproduction Assay, No 229. OECD Guideline for the Testing of Chemicals 2009, Organization of Economic Cooperation and Development, Paris.
36. Orendt C., Wolfram G., Adamek Z., Jurajda P., Schmitt-Jansen M. The response of macroinvertebrate community taxa and functional groups to pollution along a heavily impacted river in Central Europe (Bilina River, Czech Republic). Biologia (Bratisl.) 2012, 67:180-199.
37. Pardo-Martin C., Chang T.Y., Koo B.K., Gilleland C.L., Wasserman S.C., Yanik M.F. High-throughput in vivo vertebrate screening. Nat. Methods 2010, 7:634-636.
38. Petersen K., Fetter E., Kah O., Brion F., Scholz S., Tollefsen K.E. Transgenic (cyp19a1b-GFP) zebrafish embryos as a tool for assessing combined effects of oestrogenic chemicals. Aquat. Toxicol. 2013, 138-139:88-97.
39. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001, 29:e45.
40. Quesada-Garcia A., Valdehita A., Torrent F., Villarroel M., Hernando M.D., Navas J.M. Use of fish farms to assess river contamination: combining biomarker responses, active biomonitoring, and chemical analysis. Aquat. Toxicol. 2013, 140-141:439-448.
41. Racz L., Goel R.K. Fate and removal of estrogens in municipal wastewater. J. Environ. Monit. 2010, 12:58-70.
42. Rastall A.C., Getting D., Goddard J., Roberts D.R., Erdinger L. A biomimetic approach to the detection and identification of estrogen receptor agonists in surface waters using semipermeable membrane devices (SPMDs) and bioassay-directed chemical analysis. Environ. Sci. Pollut. Res. Int. 2006, 13:256-267.
43. Schmitt C., Balaam J., Leonards P., Brix R., Streck G., Tuikka A., Bervoets L., Brack W., van Hattum B., Meire P., de Deckere E. Characterizing field sediments from three European river basins with special emphasis on endocrine effects - a recommendation for Potamopyrgus antipodarum as test organism. Chemosphere 2010, 80:13-19.
44. Schmitt S., Reifferscheid G., Claus E., Schlüsener M., Buchinger S. Effect directed analysis and mixture effects of estrogenic compounds in a sediment of the river Elbe. Environ. Sci. Pollut. Res. Int. 2012, 19:3350-3361.
45. Scholz S. Zebrafish embryos as an alternative model for screening of drug-induced organ toxicity. Arch. Toxicol. 2013, 87:767-769.
46. Scholz S., Klüver N. Effects of endocrine disrupters on sexual, gonadal development in fish. Sexual Dev. 2009, 3:136-151.
47. Scholz S., Mayer I. Molecular biomarkers of endocrine disruption in small model fish. Mol. Cell. Endocrinol. 2008, 293:57-70.
48. Scholz S., Renner P., Belanger S.E., Busquet F., Davi R., Demeneix B.A., Denny J.S., Leonard M., McMaster M.E., Villeneuve D.L., Embry M.R. Alternatives to in vivo tests to detect endocrine disrupting chemicals (EDCs) in fish and amphibians - screening for estrogen, androgen and thyroid hormone disruption. Crit. Rev. Toxicol. 2013, 43:45-72.
49. Silva E., Rajapakse N., Kortenkamp A. Something from nothing - eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects. Environ. Sci. Technol. 2002, 36:1751-1756.
50. Strähle U., Scholz S., Geisler R., Greiner P., Hollert H., Rastegar S., Schumacher A., Selderslaghs I., Weiss C., Witters H., Braunbeck T. Zebrafish embryos as an alternative to animal experiments - a commentary on the definition of the onset of protected life stages in animal welfare regulations. Reprod. Toxicol. 2012, 33:128-132.
51. Tong S.K., Mouriec K., Kuo M.W., Pellegrini E., Gueguen M.M., Brion F., Kah O., Chung B.C. A cyp19a1b-gfp (aromatase B) transgenic zebrafish line that expresses GFP in radial glial cells. Genesis 2009, 47:67-73.
52. USEPA Fish Short-Term Reproduction Assay, Endocrine disruptor screening Program Test Guidelines, OPPTS 890.1350 2009, United States Environmental Protection Agency, Washington, DC.
53. Vosges M., Le Page Y., Chung B.C., Combarnous Y., Porcher J.M., Kah O., Brion F. 17alpha-ethinylestradiol disrupts the ontogeny of the forebrain GnRH system and the expression of brain aromatase during early development of zebrafish. Aquat. Toxicol. 2010, 99:479-491.
54. Wang L., Ying G.G., Chen F., Zhang L.J., Zhao J.L., Lai H.J., Chen Z.F., Tao R. Monitoring of selected estrogenic compounds and estrogenic activity in surface water and sediment of the Yellow River in China using combined chemical and biological tools. Environ. Pollut. 2012, 165:241-249.
55. Wang R.L., Biales A., Bencic D., Lattier D., Kostich M., Villeneuve D., Ankley G.T., Lazorchak J., Toth G. DNA microarray application in ecotoxicology: experimental design, microarray scanning, and factors affecting transcriptional profiles in a small fish species. Environ. Toxicol. Chem. 2008, 27:652-663.
56. Westerfield M. The zebrafish book: a guide for the laboratory use of zebrafish (Brachydanio rerio) 1993, University of Oregon Press, Eugene, OR, United States.
57. Yang Y.Y., Gray J.L., Furlong E.T., Davis J.G., Revello R.C., Borch T. Steroid hormone runoff from agricultural test plots applied with municipal biosolids. Environ. Sci. Technol. 2012, 46:2746-2754.