Zebrafish embryos as an alternative model for screening of drug-induced organ toxicity

Archives of Toxicology

Volumn 87, Issue 5, 2013, Pages 767-769

  Scholz, S ^a  

^a HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; BIOLOGICAL MODEL; DEVELOPMENTAL BIOLOGY; EDITORIAL; EMBRYO; EMBRYO (ANATOMY); EMBRYO DEVELOPMENT; GOVERNMENT REGULATION; HUMAN; IN VITRO STUDY; LIVER TOXICITY; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; TELEOST; TERATOGENICITY; VERTEBRATE; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; ANIMAL TESTING ALTERNATIVE; DISEASE MODEL; DRUG EFFECT; DRUG SCREENING; METABOLISM; METHODOLOGY; PHYSIOLOGY;

DANIO RERIO;

XENOBIOTIC AGENT;

ANIMAL TESTING ALTERNATIVES; ANIMALS; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; EMBRYO, NONMAMMALIAN; XENOBIOTICS; ZEBRAFISH;

EID: 84886942842     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1044-2     Document Type: Editorial

References (31)

1. Aanes H, Winata CL, Lin CH, Chen JP, Srinivasan KG, Lee SGP, Lim AYM, Hajan HS, Collas P, Bourque G, Gong Z, Korzh V, Aleström P, Mathavan S (2011). Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition. Genome Res 21:1328-1338. doi:10.1101/gr.116012.110
2. Ali S, Mil HGJv, Richardson MK (2011) Large-scale assessment of the zebrafish embryo as a possible predictive model in toxicity testing. PLoS ONE 6:e21076
3. Berghmans S, Butler P, Goldsmith P, Waldron G, Gardner I, Golder Z, Richards FM, Kimber G, Roach A, Alderton W, Fleming A (2008) Zebrafish based assays for the assessment of cardiac, visual and gut function-potential safety screens for early drug discovery. J Pharmacol Toxicol Methods 58:59-68
4. Brion F, Le Page Y, Piccini B, Cardoso O, Tong S-K, Chung B-c, Kah O (2012) Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos. PlosOne 7:e36069
5. Busch W, Duis K, Fenske M, Maack G, Legler J, Padilla S, Strähle U, Witters H, Scholz S (2011) The zebrafish embryo model in toxicology and teratology, September 2-3, 2010, Karlsruhe, Germany. Reprod Toxicol 31:585-588
6. Büttner A, Busch W, Klüver N, Giannis A, Scholz S (2012) Transcriptional responses of zebrafish embryos exposed to potential sonic hedgehog pathway interfering compounds deviate from expression profiles of cyclopamine. Reprod Toxicol 33:254-263
7. Cui C, Benard EL, Kanwal Z, Stockhammer OW, van der Vaart M, Zakrzewska A, Spaink HP, Meijer AH (2011) Infectious disease modelling and innate immune function in zebrafish embryos. Methods Cell Biol 105:273-308
8. Driessen M, Kienhuis AS, Pennings JLA, Pronk TE, van den Brandhof EJ, Roodbergen M, Spaink HP, van de Water B, van der Ven LTM (2013). Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling. Arch Toxicol (this issue)
9. Embry MR, Belanger SE, Braunbeck TA, Galay-Burgos M, Halder M, Hinton DE, Léonard MA, Lillicrap A, Norberg-King T, Whale G (2010) The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research. Aquat Toxicol 97:79-87
10. EU (2010) Directive 2010/63/EU of the European parliament and of the council of 22 September 2010 on the protection of animals used for scientific purposes. OJ Eur Comm L 276:34-79
11. Gorge G, Nagel R (1990) Toxicity of lindane, atrazine, and deltamethrin to early life stages of zebrafish (Brachydanio rerio). Ecotoxicol Environ Saf 20:246-255
12. Gündel U, Kalkhof S, Zitzkat D, von Bergen M, Altenburger R, Küster E (2012) Concentration-response concept in ecotoxicoproteomics: effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome. Ecotoxicol Environ Saf 76:11-22
13. Gustafson AL, Stedman DB, Ball J, Hillegass JM, Flood A, Zhang CX, Panzica-Kelly J, Cao J, Coburn A, Enright BP, Tornesi MB, Hetheridge M, Augustine-Rauch KA (2012) Inter-laboratory assessment of a harmonized zebrafish developmental toxicology assay-progress report on phase I. Reprod Toxicol 33:155-164
14. Halder M, Léonard M, Iguchi T, Oris JT, Ryder K, Belanger SE, Braunbeck TA, Embry MR, Whale G, Norberg-King T, Lillicrap A (2010) Regulatory aspects on the use of fish embryos in environmental toxicology. Integr Environ Assess Manag 6:484-491
15. Hermsen SAB, Pronk TE, van den Brandhof E-J, van der Ven LTM, Piersma AH (2012) Concentration-response analysis of differential gene expression in the zebrafish embryotoxicity test following flusilazole exposure. Tox Sci 127:303-312
16. Klüver N, Yang L, Busch W, Scheffler K, Renner P, Strähle U, Scholz S (2011). Transcriptional response of zebrafish embryos exposed to neurotoxic compounds reveals a muscle activity dependent hspb11 expression. PLoS ONE. doi:10.1371/journal.pone. 0029063
17. Kokel D, Bryan J, Laggner C, White R, Cheung CYJ, Mateus R, Healey D, Kim S, Werdich AA, Haggarty SJ, MacRae CA, Shoichet B, Peterson RT (2010) Rapid behavior-based identification of neuroactive small molecules in the zebrafish. Nat Chem Biol 6:231-237
18. Lammer E, Carr GJ, Wendler K, Rawlings JM, Belanger SE, Braunbeck T (2009) Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test? Comp Biochem Phys C 149:196-209
19. Louisse J, de Jong E, van de Sandt JJM, Blaauboer BJ, Woutersen RA, Piersma AH, Rietjens IMCM, Verwei M (2010) The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man. Tox Sci 118:470-484
20. Noorlander C, Zeilmaker M, Eijkeren Jv, Bourgeois F, Beffers R, Brandon E, Bessems J (2008). Data collection on kinetic parameters of substances. Pilot phase-A methodological report-December 2008 CCR.IHCP.C432921.XO. Available at http://ecvam.jrc.it
21. Padilla S, Corum D, Padnos B, Hunter DL, Beam A, Houck KA, Sipes N, Kleinstreuer N, Knudsen T, Dix DJ, David RM (2012) Zebrafish developmental screening of the ToxCast(TM) phase 1 chemical library. Reprod Toxicol 33:174-187
22. Parng C, Seng WL, Semino C, McGrath P (2002) Zebrafish: a preclinical model for drug screening. Assay Drug Dev Technol 1:41-48
23. Pelayo S, Oliveira E, Thienpont B, Babin PJ, Raldua D, Andre M, Pina B (2012) Triiodothyronine-induced changes in the zebrafish transcriptome during the eleutheroembryonic stage: implications for bisphenol A developmental toxicity. Aquat Toxicol 110: 114-122
24. Schiller V, Wichmann A, Kriehuber R, Muth-Kohne E, Giesy JP, Hecker M, Fenske M (2012) Studying the effects of genistein on gene expression of fish embryos as an alternative testing approach for endocrine disruption. Comp Biochem Phys C 157:41-53
25. Selderslaghs IWT, Van Rompay AR, De Coen W, Witters HE (2009) Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish embryo. Reprod Toxicol 28:308-320
26. Selderslaghs IWT, Hooyberghs J, De Coen W, Witters HE (2010) Locomotor activity in zebrafish embryos: a new method to assess developmental neurotoxicity. Neurotoxicol Teratol 32:460-471
27. Strähle U, Scholz S, Geisler R, Greiner P, Hollert H, Rastegar S, Schumacher A, Selderslaghs I, Weiss C, Witters H, Braunbeck T (2012) Zebrafish embryos as an alternative to animal experiments-A commentary on the definition of the onset of protected life stages in animal welfare regulations. Reprod Toxicol 33:128-132
28. Thienpont B, Tingaud-Sequeira A, Prats E, Barata C, Babin PJ, Raldua D (2011) Zebrafish eleutheroembryos provide a suitable vertebrate model for screening chemicals that impair thyroid hormone synthesis. Environ Sci Technol 45:7525-7532
29. Vesterlund L, Jiao H, Unneberg P, Hovatta O, Kere J (2011) The zebrafish transcriptome during early development. BMC Dev Biol 11:30
30. Volz DC, Belanger S, Embry M, Padilla S, Sanderson H, Schirmer K, Scholz S, Villeneuve D (2011) Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies. Tox Sci 123:349-358
31. Yang L, Kemadjou JR, Zinsmeister C, Bauer M, Legradi J, Müller F, Pankratz M, Jäkel J, Strähle U (2007) Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo. Genome Biol 8:R227