17α-Ethinylestradiol disrupts the ontogeny of the forebrain GnRH system and the expression of brain aromatase during early development of zebrafish

Aquatic Toxicology

Volumn 99, Issue 4, 2010, Pages 479-491

  Vosges, Mélanie ^a   Le Page, Yann ^b   Chung, Bon Chu ^c   Combarnous, Yves ^d   Porcher, Jean Marc ^a   Kah, O ^b   Brion, François ^a  

^a INSTITUT NATIONAL DE L ENVIRONNEMENT INDUSTRIEL ET DES RISQUES INERIS   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^d UMR85 PHYSIOLOGIE DE LA REPRODUCTION ET DES COMPORTEMENTS   (France)

Author keywords

(Neuro ) endocrine disruption; 17 Ethinylestradiol (EE2); Aromatase B (cyp19a1b); Development; Gonadotropin releasing hormone (GnRH); Zebrafish (Danio rerio)

Indexed keywords

AROMATASE; ETHINYLESTRADIOL; GONADORELIN; CYP19B PROTEIN, ZEBRAFISH; ENDOCRINE DISRUPTOR; ZEBRAFISH PROTEIN;

BIOMARKER; CYPRINID; EMBRYONIC DEVELOPMENT; ENDOCRINE DISRUPTOR; ENZYME ACTIVITY; ONTOGENY; POLLUTION EFFECT;

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN NERVE CELL; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FOREBRAIN; GLIA CELL; MALE; NONHUMAN; ONTOGENY; PERIKARYON; PRIORITY JOURNAL; PROTEIN EXPRESSION; ZEBRA FISH; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; ENDOPLASMIC RETICULUM; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; METABOLISM; NERVE CELL; NONPARAMETRIC TEST; PRENATAL DEVELOPMENT; TIME;

DANIO RERIO; VERTEBRATA;

ANIMALS; AROMATASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; ENDOPLASMIC RETICULUM; ETHINYL ESTRADIOL; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GONADOTROPIN-RELEASING HORMONE; IMMUNOHISTOCHEMISTRY; NEURONS; PROSENCEPHALON; STATISTICS, NONPARAMETRIC; TIME FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 77957756097     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2010.06.009     Document Type: Article

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