Alpha1a-adrenoceptor genetic variant induces cardiomyoblast-to-fibroblast-like cell transition via distinct signaling pathways

Cellular Signalling

Volumn 26, Issue 9, 2014, Pages 1985-1997

  Kleine Brueggeney, Maren ^a,c   Gradinaru, Irina ^a   Babaeva, Ekaterina ^a   Schwinn, Debra A ^a,b,d,e   Oganesian, Anush ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF BERN   (Switzerland)

^d UNIVERSITY OF IOWA   (United States)

^e UNIVERSITY OF IOWA   (United States)

Author keywords

Adrenergic receptor; Epidermal growth factor receptor (EGFR); G protein coupled receptors (GPCRs); Genetic variant; Matrix metalloproteinases (MMPs); Transactivation

Indexed keywords

ALPHA 1A ADRENERGIC RECEPTOR; BETA ARRESTIN 1; EPIDERMAL GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ALPHA 1 ADRENERGIC RECEPTOR; BETA ARRESTIN; DIPEPTIDE; N-(2(R)-2-(HYDROXAMIDOCARBONYLMETHYL)-4-METHYLPENTANOYL)-L-TRYPTOPHAN METHYLAMIDE; PHENYLEPHRINE; QUINAZOLINE DERIVATIVE; RETINA S ANTIGEN; TYRPHOSTIN;

ALPHA 1A ADRENERGIC RECEPTOR GENE; ANIMAL CELL; ARTICLE; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENETIC VARIABILITY; HEART ARRHYTHMIA; HEART MUSCLE CELL; MOLECULAR PATHOLOGY; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; FIBROBLAST; GENETICS; HUMAN; METABOLISM; MUTATION; MYOBLAST; PHOSPHORYLATION; TRANSCRIPTION INITIATION;

ANIMALS; ARRESTINS; CELL LINE; CELL PROLIFERATION; DIPEPTIDES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HUMANS; MATRIX METALLOPROTEINASES; MUTATION; MYOBLASTS, CARDIAC; PHENYLEPHRINE; PHOSPHORYLATION; QUINAZOLINES; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, ADRENERGIC, ALPHA-1; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TRANSCRIPTIONAL ACTIVATION; TYRPHOSTINS;

EID: 84902148583     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.05.007     Document Type: Article

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