The -344C/T polymorphism in the CYP11B2 gene is associated with essential hypertension in the Chinese

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 15, Issue 2, 2014, Pages 150-155

  Li, Weixing ^a   Liu, Chibo ^b  

^a ZHEJIANG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b TAIZHOU MUNICIPAL HOSPITAL   (China)

Author keywords

Chinese; CYP11B2; Hypertension; meta analysis; polymorphism

Indexed keywords

ALDOSTERONE SYNTHASE;

ARTICLE; CODOMINANCE; DATA BASE; DNA POLYMORPHISM; ESSENTIAL HYPERTENSION; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; HAN CHINESE; HUMAN; META ANALYSIS; RISK FACTOR; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; ETHNIC GROUP; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; HYPERTENSION; PATHOPHYSIOLOGY;

ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; CYTOCHROME P-450 CYP11B2; ETHNIC GROUPS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; POLYMORPHISM, GENETIC;

EID: 84902133550     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320312466928     Document Type: Article

References (45)

1. Lawes CM, Vander Hoorn S, Rodgers A. Global burden of blood-pressure-related disease, 2001. Lancet. 2008 ; 371: 1513-1518
2. Whelton PK, He J, Appel LJ, et al. Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education Program. JAMA. 2002 ; 288: 1882-1888
3. Levy D, DeStefano AL, Larson MG, et al. Evidence for a blood pressure gene on chromosome 17: Genome scan results for longitudinal blood pressure phenotypes in subjects from the Framingham Heart Study. Hypertension. 2000 ; 36: 477-483
4. Newton-Cheh C, Johnson T, Gateva V, et al. Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet. 2009 ; 41: 666-676
5. Levy D, Ehret GB, Rice K, et al. Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009 ; 41: 677-687
6. Kato N, Takeuchi F, Tabara Y, et al. Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet. 2011 ; 43: 531-538
7. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 ; 478: 103-109
8. Poch E, González D, Giner V, et al. Molecular basis of salt sensitivity in human hypertension. Evaluation of renin-angiotensin-aldosterone system gene polymorphisms. Hypertension. 2001 ; 38: 1204-1209
9. Connell JM, Fraser R, MacKenzie SM, et al. The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation. Mol Cell Endocrinol. 2004 ; 217: 243-247
10. Sookoian S, Gianotti TF, González CD, et al. Association of the C-344T aldosterone synthase gene variant with essential hypertension: A meta-analysis. J Hypertens. 2007 ; 25: 5-13
11. Takeuchi F, Yamamoto K, Katsuya T, et al. Reevaluation of the association of seven candidate genes with blood pressure and hypertension: a replication study and meta-analysis with a larger sample size. Hypertens Res. 2012 ; 35: 825-831
12. Cheng X, Xu G. Association between aldosterone synthase CYP11B2 polymorphism and essential hypertension in Chinese: A meta-analysis. Kidney Blood Press Res. 2009 ; 32: 128-140
13. Cheng X, Xu G. A systemic review of the relationship between aldosterone synthase - 344 C/T polymorphism and hypertension in Han. Clin Exp Hypertens. 2010 ; 32: 301-307
14. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986 ; 7: 177-188
15. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959 ; 22: 719-748
16. Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics. 1994 ; 50: 1088-1101
17. Egger M, Davey Smith G, Schneider M, et al. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997 ; 315: 629-634
18. Tang W, Wu H, Zhou X, et al. Association of the C-344T polymorphism of CYP11B2 gene with essential hypertension in Hani and Yi minorities of China. Clin Chim Acta. 2006 ; 364: 222-225
19. Xu XJ, Li J, Liang XH, et al. Relationship between the -344T/C polymorphism of aldosterone synthase gene and essential hypertension in Uygur, Han and Kazak population in Xinjiang. Journal of Xinjiang Medical University. 2009 ; 32: 105-108
20. MiDQ. Association of polymorphisms in the EMILIN1 and CYP11B2 genes with essential hypertension in Mongolian and Dai Chinese population. Master degree candidate dissertation of Peking Union Medical College, 2011; 1-65.
21. Chen AH, Zhang WX, Tang XM, et al. The relationship of aldosterone synthase gene polymorphism with hypertension and left ventricular hypertrophy. Chin J Intern Med. 2002 ; 41: 298-301
22. Yuan GX, Ha DW. Association between aldosterone synthase gene -344C/T polymorphism and essential hypertension in Chinese population. Chinese Circulation Journal. 2002 ; 17: 118-120
23. Hu XJ, Wang F, Wang JM, et al. Association between aldosterone synthase gene polymorphism and primary hypertension in Chinese Han population. J Clin Cardiol (China). 2003 ; 19: 456-458
24. XieLF. Hypertension and artery stiffness in relation to four candidate genes in the Han nationality population. Doctoral candidate dissertation of Peking Union Medical College, 2003; 1-106.
25. Gu D, Ge D, He J, et al. Haplotypic analyses of the aldosterone synthase gene CYP11B2 associated with stage-2 hypertension in northern Han Chinese. Clin Genet. 2004 ; 66: 409-416
26. Wang R, Wang JM, Xie YS, et al. Relationship of aldosterone synthase gene polymorphism with essential hypertension and plasma aldosterone levels. J Clin Intern Med. 2004 ; 21: 524-526
27. Jiang XL, Huang XM, Duan YF, et al. Relationship of polymorphism of aldosterone synthase gene with essential hypertension and blood lipids in high-risk population of hypertension in Han and Dong nationality population in Huaihua. Chinese Journal of Clinical Rehabilitation. 2005 ; 31: 61-63
28. Chen D, Wang L, Xue Y, et al. Association between a polymorphism of aldosterone synthase gene and essential hypertension. Journal of Dalian Medical University. 2006 ; 28: 446-449
29. Hu BC, Chu SL, Wang JG, et al. Association of aldosterone synthase gene -344T/C polymorphism with plasma aldosterone and angiotensin II concentration in hypertensive patients. Natl Med J China. 2006 ; 86: 1144-1147
30. Hua Q, Xu J, Li DB, et al. The influence of gene polymorphism of aldosterone synthase gene -344T/C on RAAS in Han nationality essential hypertensive patients in Beijing. Journal of Capital University of Medical Sciences. 2006 ; 27: 361-364
31. Li QX, Gao H, Xu FX, et al. Correlativity between the polymorphisms of aldosterone synthase gene, Hind III restriction site on Y chromosome and essential hypertension. Chin J Med Genet. 2006 ; 23: 294-297
32. He FR, He XY, Shen GX, et al. The relationship of CYP11B2-344T/C polymorphism with hypertension and metabolic syndrome in Wuhan of China. Chinese Journal of Micocirculation. 2007 ; 17: 26-28
33. Hu RL, Zhang CY, Zhao SG, et al. Association of ACE I/D variant and CYP11B2 T-344C variant with essential hypertension in the Mongolian. Chinese Journal of Gerontology. 2007 ; 27: 1166-1168
34. Niu WQ, Wang JB, Li SJ, et al. Relationship between aldosterone synthase gene (CYP11B2) polymorphism and essential hypertension in a Northern Chinese Han Population. Acta Academiae Medicinae Sinicae. 2007 ; 29: 329-335
35. Sun XJ, Liu SR, Zhang CH, et al. Association of aldosterone synthase gene -344T/C polymorphism with early renal damage in Han nationality with essential hypertension. Chin J Med Genet. 2007 ; 24: 153-156
36. Wu XY, Li DY, Chen H, et al. Study on the association between ACE, CYP11B2 genes polymorphisms and essential hypertension complicated with Ischemic cerebrovascular disease. Molecular Cardiology of China. 2008 ; 8: 34-38
37. Peng H, Hu XJ, Chen S, et al. Relationship between the polymorphism of aldosterone synthase gene and essential hypertension in elderly population. Chinese Journal of Gerontology. 2010 ; 30: 1326-1327
38. TaoXM. The association of polymorphisms in the CETP gene and CYP11B2 gene with essential hypertension in Chinese Mongolian population. Master degree candidate dissertation of Peking Union Medical College, 2010; 1-62.
39. Zhao L, Guo XH. Relationship between the -344T/C polymorphism of aldosterone synthase gene and essential hypertension and cerebral infarction in Korean Chinese population. Shandong Medical Journal. 2010 ; 50: 67-68
40. Chen B, Nie S, Luo S, et al. Association of the Human CYP11B2 Gene and Essential Hypertension in Southwest Han Chinese Population: A Haplotype-Based Case-Control Study. Clin Exp Hypertens. 2011 ; 33: 106-112
41. Li XM, Ling Y, Lu DR, et al. Association of the aldosterone synthase gene -344T>C polymorphism with essential hypertension and glucose homeostasis: a case-control study in a Han Chinese population. Clin Exp Pharmacol Physiol. 2011 ; 38: 598-604
42. Gong HT, Ma XL, Du FH. Association of polymorphism of angiotensin converting enzyme gene and aldosterone synthase gene with essential hypertension. Chinese General Practice. 2011 ; 14: 2609-2611
43. Thaler RH The Winner's Curse: Paradoxes and Anomalies of Economic Life. Princeton, NJ: Princeton University Press ; 1999:
44. Clyne CD, Zhang Y, Slutsker L, et al. Angiotensin II and potassium regulate human CYP11B2 transcription through common cis-elements. Mol Endocrinol. 1997 ; 11: 638-649
45. Nicod J, Bruhin D, Auer L, et al. A biallelic gene polymorphism of CYP11B2 predicts increased aldosterone to renin ratio in selected hypertensive patients. J Clin Endocrinol Metab. 2003 ; 88: 2495-2500