Relationship between aidosterone synthase gene (CYP11B2) polymorphisms and essential hypertension in a northern Chinese Han population

Acta Academiae Medicinae Sinicae

Volumn 29, Issue 3, 2007, Pages 329-335

  Niu, Wen Quan ^a   Wang, Jian Bing ^b   Li, Su Jie ^c   Zhou, Wen Yu ^a   Zhao, Jing Bo ^b   Qiu, Chang Chun ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b HARBIN MEDICAL UNIVERSITY   (China)

^c Heilongjiang Power Hospital   (China)

Author keywords

Aldosterone synthase gene; Essential hypertension; Polymorphism

Indexed keywords

ALDOSTERONE SYNTHASE;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CHINESE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOMINANT INHERITANCE; ESSENTIAL HYPERTENSION; FEMALE; GENE FREQUENCY; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PROMOTER REGION; PULSE PRESSURE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE ANALYSIS; SEX DIFFERENCE; SMOKING; SYSTOLIC BLOOD PRESSURE; SYSTOLIC HYPERTENSION; WAIST HIP RATIO; ASIAN; CASE CONTROL STUDY; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; HYPERTENSION;

ALDOSTERONE SYNTHASE; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; MALE; POLYMORPHISM, GENETIC;

EID: 34447530504     PISSN: 1000503X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Santoro G, Bigaszi MC, Palladino MT, et al. Comparison of pereutaneous closure of large patent ductus arteriosus by multiple coils versus the Amplatzer duct occluder device [J]. Am J Cardiol, 2004, 94(2):252-255.
2. Lifton RP, Gharavi AG, Geller DS. Molecular mechanisms of human hypertension [J]. Cell, 2001, 104(4):545-556.
3. Tanira MO, Al Balushi KA. Genetic variations related to hypertension: a review [J]. J Hum Hypertens, 2005, 19 (1):7-19.
4. Saeed M, Saleheen D, Siddiqui S, et al. Association of angiotensin converting enzyme gene polymorphisms with left ventricular hypertrophy [J]. Hypertens Res, 2005, 28 (4):345-349.
5. Pereira AC, Mota GF, Cunha RS, et al. Angiotensinogen 235T allele "dosage" is associated with blood pressure phenotypes [J]. Hypertension, 2003, 41(1):25-30.
6. Duprez DA. Role of the renin-angiotensin-aldosterone system in vascular remodeling and inflammation: a clinical review [J]. J Hypertens, 2006, 24(6):983-991.
7. Rajput C, Makhijani K, Norboo T, et al. CYP11B2 gene polymorphisms and hypertension in highlanders accustomed to high salt intake [J]. J Hypertens, 2005, 23(1):79-86.
8. Hautanen A, Toivanen P, Manttari M, et al. Joint effects of an aldosterone synthase (CYP11B2) gene polymorphism and classic risk factors on risk of myocardial infarction [J]. Circulation, 1999, 100(22):2213-2218.
9. Paillard F, Chansel D, Brand E, et al. Genotype-phenotype relationships for the renin-angiotensin-aldosterone system in a normal population [J]. Hypertension, 1999, 34(3):423-429.
10. Tamaki S, Iwai N, Tsujita Y, et al. Genetic polymorphism of CYP11B2 gene and hypertension in Japanese [J]. Hypertension, 1999, 33(1):266-270.
11. Chinese source.
12. Chinese source.
13. Chinese source.
14. Rajput C, Makhijani K, Norboo T, et al. CYP11B2 gene polymorphisms and hypertension in highlanders accustomed to high salt intake [J]. J Hypertens, 2005, 23(1):79-86.
15. Komiya I, Yamada T, Takara M, et al. Lys (173) Arg and -344T/C variants of CYP11B2 in Japanese patients with low-renin hypertension [J]. Hypertension, 2000, 35(3): 699-703.
16. Jacob KN, Baptista F, dos Santos HG, et al. Phenotypic heterogeneity in body fat distribution in patients with atypical werner's syndrome due to heterozygous Arg133Leu Lamin A/C Mutation [J]. J Clin Endocrinol Metab, 2005, 90(12): 6699-6706.
17. Fardella CE, Rodriguez H, Montero J, et al. Genetic variation in P450c11AS in Chilean patients with low renin hypertension [J]. J Clin Endocrinol Metab, 1996, 81(12): 4347-4351.