Systemic injection of low-dose lipopolysaccharide fails to break down the blood-brain barrier or activate the TLR4-MyD88 pathway in neonatal rat brain

International Journal of Molecular Sciences

Volumn 15, Issue 6, 2014, Pages 10101-10115

  Wang, Peng ^a,b   You, Si Wei ^a   Yang, Yin Jie ^c   Wei, Xiao Yan ^a   Wang, Ya Zhou ^a   Wang, Xin ^b   Hao, Ding Jun ^d   Kuang, Fang ^a   Shang, Li Xin ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c The 425th People's Liberation Army Hospital   (China)

^d Xi'an Red Cross Hospital   (China)

Author keywords

Blood brain barrier; Low dose lipopolysaccharide; Neonatal; Rat; Toll like receptor 4

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN P50; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; EXTRAVASATION; FEMALE; HEMISPHERE; IMMUNOHISTOCHEMISTRY; LOW DRUG DOSE; MALE; MICROGLIA; MORPHOLOGY; NEWBORN; NONHUMAN; PERMEABILITY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; IMMUNOLOGY; INJECTION; MICROBIOLOGY; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ANIMALS; ANIMALS, NEWBORN; BLOOD-BRAIN BARRIER; FEMALE; INJECTIONS; LIPOPOLYSACCHARIDES; MALE; MICROGLIA; MYELOID DIFFERENTIATION FACTOR 88; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84901981642     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150610101     Document Type: Article

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