Insights into the binding of pyridines to the iron-sulfur enzyme IspH

Journal of the American Chemical Society

Volumn 136, Issue 22, 2014, Pages 7926-7932

  Span, Ingrid ^a,d   Wang, Ke ^b   Eisenreich, Wolfgang ^a   Bacher, Adelbert ^a   Zhang, Yong ^c   Oldfield, Eric ^b   Groll, Michael ^a  

^a Munich Center for Integrated Protein Science   (Germany)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c Stevens Institute of Technology   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; ENZYME ACTIVITY; ESCHERICHIA COLI; IRON; ORGANOMETALLICS; QUANTUM CHEMISTRY; QUANTUM THEORY; X RAY CRYSTALLOGRAPHY;

HYPERFINE COUPLING; ISOPRENOID BIOSYNTHESIS; MALARIA PARASITE; MODE OF BINDING; ORGANO-METALLIC COMPLEXES; QUADRUPOLE COUPLING CONSTANTS; QUANTUM CHEMICAL CALCULATIONS; X-RAY STRUCTURE;

PYRIDINE;

(PYRIDIN 3 YL)METHYL DIPHOSPHATE; 1 HYDROXY 2 METHYLBUT 2 ENYL 4 DIPHOSPHATE REDUCTASE; CARBON; IRON; IRON SULFUR PROTEIN; NITROGEN; OXIDOREDUCTASE; PYRIDINE DERIVATIVE; PYROPHOSPHATE; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN; ISPH PROTEIN, E COLI; LIGAND; PROTEIN BINDING; SULFUR;

ARTICLE; BINDING KINETICS; DENSITY FUNCTIONAL THEORY; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; NONHUMAN; QUANTUM CHEMISTRY; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; QUANTUM THEORY;

CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; IRON-SULFUR PROTEINS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES; PROTEIN BINDING; PROTEIN CONFORMATION; PYRIDINES; QUANTUM THEORY; SULFUR;

EID: 84901944485     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja501127j     Document Type: Article

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