Structures of fluoro, amino, and thiol inhibitors bound to the [Fe 4S4] protein IspH

Angewandte Chemie - International Edition

Volumn 52, Issue 7, 2013, Pages 2118-2121

  Span, Ingrid ^a   Wang, Ke ^b   Wang, Weixue ^b   Jauch, Johann ^c   Eisenreich, Wolfgang ^a   Bacher, Adelbert ^a   Oldfield, Eric ^b   Groll, Michael ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

bioinorganic chemistry; IspH; LytB; metalloenzymes; terpenoids

Indexed keywords

BIOINORGANIC CHEMISTRY; ISPH; LYTB; METALLOENZYMES; TERPENOIDS;

BIOCHEMISTRY; LIPIDS;

PROTEINS;

AMINE; ENZYME INHIBITOR; ESCHERICHIA COLI PROTEIN; FLUORINE; ISPH PROTEIN, E COLI; OXIDOREDUCTASE; THIOL DERIVATIVE;

ARTICLE; BINDING SITE; CHEMISTRY; DRUG ANTAGONISM; ENZYME ACTIVE SITE; ENZYMOLOGY; ESCHERICHIA COLI; METABOLISM; X RAY CRYSTALLOGRAPHY;

AMINES; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FLUORINE; OXIDOREDUCTASES; SULFHYDRYL COMPOUNDS;

EID: 84873564946     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201208469     Document Type: Article

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