Cucurbitacin-I, a natural cell-permeable triterpenoid isolated from Cucurbitaceae, exerts potent anticancer effect in colon cancer

Chemico-Biological Interactions

Volumn 219, Issue , 2014, Pages 1-8

  Kim, Hyeon Jin ^a   Park, Jung Han Yoon ^b   Kim, Jin Kyung ^a  

^a Catholic University of Daegu   (South Korea)

^b Hallym University   (South Korea)

Author keywords

Apoptosis; CT 26 cells; Cucurbitacin I; G2 M arrest; SW480 cells

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CELL CYCLE PROTEIN; CUCURBITACIN I; CYCLIN A; CYCLIN B1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN CDC25C; PROTEIN CDK1; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN TYROSINE PHOSPHATASE; TRITERPENOID; CASPASE; CCNB1 PROTEIN, HUMAN; CDC25C PROTEIN, HUMAN; CDK1 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE; PARP1 PROTEIN, HUMAN; TRITERPENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOGENICITY; CELL PROLIFERATION; CELL VIABILITY; COLON CARCINOMA; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; TUMOR VOLUME; CANCER CELL CULTURE; CELL CYCLE ARREST; COLON CANCER; CONCENTRATION RESPONSE; CUCURBITACEAE; ENZYME DEGRADATION; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; TUMOR GROWTH; ANIMAL; BAGG ALBINO MOUSE; CELL CYCLE CHECKPOINT; CELL SURVIVAL; CHEMISTRY; COLONIC NEOPLASMS; DRUG EFFECTS; FLOW CYTOMETRY; METABOLISM; NEOPLASMS, EXPERIMENTAL; PHYSIOLOGY; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CDC25 PHOSPHATASES; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; COLONIC NEOPLASMS; CUCURBITACEAE; CYCLIN A; CYCLIN B1; CYCLIN-DEPENDENT KINASES; FLOW CYTOMETRY; HUMANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED BALB C; NEOPLASMS, EXPERIMENTAL; POLY(ADP-RIBOSE) POLYMERASES; TRITERPENES;

EID: 84901930508     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2014.05.005     Document Type: Article

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