Chemopreventive and metabolic effects of inulin on colon cancer development

Journal of Veterinary Science

Volumn 14, Issue 4, 2013, Pages 387-393

  Hijová, Emília ^a   Szabadosova, Viktória ^a   Štofilová, Jana ^a   Hrčková, Gabriela ^b  

^a P J AFÁRIK UNIVERSITY   (Slovakia)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Chemoprevention; Colon cancer; Prebiotic; Sprague Dawley rats

Indexed keywords

BACTERIAL PROTEIN; CYCLOOXYGENASE 2; CYTOKINE; DIMETHYLHYDRAZINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INULIN; PREBIOTIC AGENT; PTGS2 PROTEIN, RAT; VOLATILE FATTY ACID;

ANIMAL; ARTICLE; BACTERIAL COUNT; BLOOD; CHEMICALLY INDUCED DISORDER; CHEMOPROPHYLAXIS; COLON; COLON CANCER; COLON TUMOR; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET; DIET SUPPLEMENTATION; DRUG EFFECT; ENTEROBACTERIACEAE; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LACTOBACILLACEAE; MALE; METABOLISM; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; RAT; SPRAGUE DAWLEY RAT; SPRAGUE-DAWLEY RATS;

CHEMOPREVENTION; COLON CANCER; PREBIOTIC; SPRAGUE-DAWLEY RATS;

ANIMALS; BACTERIAL PROTEINS; COLON; COLONIC NEOPLASMS; COLONY COUNT, MICROBIAL; CYCLOOXYGENASE 2; CYTOKINES; DIET; DIETARY SUPPLEMENTS; DIMETHYLHYDRAZINES; ENTEROBACTERIACEAE; FATTY ACIDS, VOLATILE; FEMALE; GENE EXPRESSION REGULATION; INULIN; LACTOBACILLACEAE; MALE; NF-KAPPA B; PREBIOTICS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84893453381     PISSN: 1229845X     EISSN: 1976555X     Source Type: Journal    
DOI: 10.4142/jvs.2013.14.4.387     Document Type: Article

References (23)

1. Bakhle YS. COX-2 and cancer: a new approach to an old problem. Br J Pharmacol 2001, 134, 1137-1150.
2. Benson AB 3rd. Epidemiology, disease progression, and economic burden of colorectal cancer. J Manag Care Pharm 2007, 13 (Suppl), S5-18.
3. Comalada M, Bailón E, de Haro O, Lara-Villoslada F, Xaus J, Zarzuelo A, Gálvez J. The effects of short-chain fatty acids on colo epithelial proliferation and survival depend on the cellular phenotype. J Cancer Res Clin Oncol 2006, 132, 487-497.
4. Chabot-Fletcher M. Transcription factor NFκB: an emerging anti-inflammatory drug target. Pharmacol Commun 1996, 8, 317-324.
5. Chen F, Castranova V, Shi X, Demers LM. New insights into the role of nuclear factor-κB, a ubiquitous transcription factor in the iniciation of diseases. Clin Chem 1999, 45, 7-17.
6. Femia AP, Salvadori M, Broekaert WF, François IEJA, Delcour JA, Courtin CM, Caderni G. Arabinoxylanoligosaccharides (AXOS) reduce preneoplastic lesions in the colon of rats treated with 1,2-dimethylhydrazine (DMH). Eur J Nutr 2010, 49, 127-132.
7. Galisteo M, Duarte J, Zarzuelo A. Effects of dietary fibers on disturbances clustered in the metabolic syndrome. J Nutr Biochem 2008, 19, 71-84.
8. Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 1995, 125, 1401-1412.
9. Gibson GR, Probert HM, Loo VJ, Rastall RA, Roberfroid MB. Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev 2004, 17, 259-275.
10. Henriques VT, Dias CMGC, Franceschini SCC, Sabarense CM, Costa NMB, Leite JIA, Peluzio MCG. Omega-3 fatty acids reduce the development of preneoplatic lesions. Rev Nutr Campinas 2009, 22, 237-244.
11. Janakiram NB, Rao CV. Molecular markers and targets for colorectal cancer prevention. Acta Pharmacol Sin 2008, 29, 1-20.
12. Juskiewicz J, Zdunczyk Z, Wroblewska M, Oszmianski J, Hernandez T. The responce of rats to feeding with diets. Food Res Int 2002, 35, 201-205.
13. Juskiewicz J, Wróblewska M, Jaroslawska J, Balinski P, Matusevicius P, Zdunczyk P, Biedrzycka E, Zdunczyk Z. Effects of inulin supplemented to cellulose-free or celluloserich diets on caecal environment and biochemical blood parameters in rats. J Anim Feed Sci 2009, 18, 709-722.
14. Al-Lahham AH, Peppelenbosch MP, Roelofsen H, Vonk RJ, Venema K. Biological effects of propionic acids in humans; metabolism, potential applications and underlying mechanisms. Biochim Biophys Acta 2010, 1801, 1175-1183.
15. Lay C, Sutren M, Lepercq P, Juste C, Rigottier-Gois L, Lhoste E, Lemée R, Le Ruyet P, Doré J, Andrieux C. Influence of Camembert consumption on the composition and metabolism of intestinal microbiota: A study in human microbiota-associated rats. Br J Nutr 2004, 92, 429-438.
16. Mathew A, Peters U, Chatterjee N, KulldorffM, Sinha R. Fat, fiber, fruits, vegetables, and risk of colorectal adenomas. Int J Cancer 2004, 108, 287-292.
17. Pan MH, Ho CT. Chemopreventive effects of natural dietary compounds on cancer development. Chem Soc Rev 2008, 37, 2558-2574.
18. Pool-Zobel BL, Sauer J. Overview of experimental data on reduction of colorectal cancer risk by inulin-type fructans. J Nutr 2007, 137, 2580S-2584S.
19. Sano H, Kawahito Y, Wilder RL, Hashiramoto A, Mukai S, Asai K, Kimura S, Kato H, Kondo M, Hla T. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res 1995, 55, 3785-3789.
20. Scharlau D, Borowicki A, Habermann N, Hofmann T, Klenow S, Miene C, Munjal U, Stein K, Glei M. Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat Res Rev Mutat Res 2009, 682, 39-53.
21. Schley PD, Field CJ. The immune-enhancing effect of dietary fibres and prebiotics. Br J Nutr 2002, 87 (Suppl), S221-230.
22. Versteeg HH, van Bergen en Henegouwen PM, van Deventer SJH, Peppelenbosch MP. Cyclooxygenasedependent signalling: molecular events and consequences. FEBS Lett 1999, 445, 1-5.
23. Wong JMW, de Souza R, Kendall CWC, Emam A, Jenkins DJA. Colonic health: fermentation and short chain fatty acids. J Clin Gastroenterol 2006, 40, 235-243.