2-(4-hydroxyphenyl)-5-(3-hydroxypropenyl)-7-methoxybenzofuran, a novel ailanthoidol derivative, exerts anti-inflammatory effect through downregulation of mitogen-activated protein kinase in lipopolysaccharide-treated RAW 264.7 cells

Korean Journal of Physiology and Pharmacology

Volumn 17, Issue 3, 2013, Pages 217-222

  Kim, Hyeon Jin ^a   Jun, Jong Gab ^b   Kim, Jin Kyung ^a  

^a Catholic University of Daegu   (South Korea)

^b Hallym University   (South Korea)

Author keywords

Ailanthoidol derivatives; AP 1; Cytokines; Inflammation; Macrophage

Indexed keywords

2 (4 BROMOPHENYL) 5 (3 HYDROXYPROPENYL) 7 METHOXYBENZOFURAN; 2 (4 CHLOROPHENYL) 5 (3 HYDROXYPROPENYL) 7 METHOXYBENZOFURAN; 2 (4 HYDROXYPHENYL) 5 (3 HYDROXYPROPENYL) 7 METHOXYBENZOFURAN; 2 (4 IODOPHENYL) 5 (3 HYDROXYPROPENYL) 7 METHOXYBENZOFURAN; 2 PHENYL 5 (3 HYDROXYPROPENYL) 7 METHOXYBENZOFURAN; 2- (2,4 DIHYDROXYPHENYL) 5 (3 HYDROXYPROPENYL) 7 METHOXYBENZOFURAN; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NEOLIGNAN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CELL VIABILITY; CYTOKINE PRODUCTION; DOWN REGULATION; IC 50; INFLAMMATORY DISEASE; MACROPHAGE; MEDIATOR RELEASE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALVIA MILTIORRHIZA; SEPTIC SHOCK; WESTERN BLOTTING; ZANTHOXYLUM;

EID: 84880372283     PISSN: 12264512     EISSN: 20933827     Source Type: Journal    
DOI: 10.4196/kjpp.2013.17.3.217     Document Type: Article

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