Increased mutability and decreased repairability of a three-lesion clustered DNA-damaged site comprised of an AP site and bi-stranded 8-oxoG lesions

International Journal of Radiation Biology

Volumn 90, Issue 6, 2014, Pages 468-479

  Cunniffe, Siobhan ^a   Walker, Alexandra ^a   Stabler, Robert ^a   O'Neill, Peter ^a   Lomax, Martine E ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

8 oxoG; AP site; Base excision repair; Clustered DNA damage; Mutagenic potential

Indexed keywords

8 HYDROXYGUANINE; DNA DIRECTED DNA POLYMERASE BETA; OLIGOMER; OLIGONUCLEOTIDE; POLYACRYLAMIDE GEL; URACIL;

ABASIC SITE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND; DNA STRUCTURE; ESCHERICHIA COLI; EXCISION REPAIR; IN VITRO STUDY; IONIZING RADIATION; MOLECULAR WEIGHT; MUTAGENESIS; MUTATION RATE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RESTRICTION SITE;

8-OXOG; AP SITE; BASE EXCISION REPAIR; CLUSTERED DNA DAMAGE; MUTAGENIC POTENTIAL;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DNA; DNA DAMAGE; DNA REPAIR; DNA, BACTERIAL; ESCHERICHIA COLI; GUANINE; MUTATION;

EID: 84901920381     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2014.899449     Document Type: Article

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