메뉴 건너뛰기




Volumn 85, Issue 6, 2014, Pages 1382-1394

Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis

Author keywords

cytoskeleton; nephrin; podocyte; signaling

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; CRK LIKE PROTEIN; CRK1 PROTEIN; CRK2 PROTEIN; NEPHRIN; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; MULTIPROTEIN COMPLEX; NUCLEAR PROTEIN; ONCOPROTEIN; PROTAMINE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

EID: 84901919445     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.556     Document Type: Article
Times cited : (34)

References (32)
  • 1
    • 34848907421 scopus 로고    scopus 로고
    • Actin up: Regulation of podocyte structure and function by components of the actin cytoskeleton
    • Faul C, Asanuma K, Yanagida-Asanuma E et al. Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton. Trends Cell Biol 2007; 17: 428-437.
    • (2007) Trends Cell Biol , vol.17 , pp. 428-437
    • Faul, C.1    Asanuma, K.2    Yanagida-Asanuma, E.3
  • 2
    • 33646400903 scopus 로고    scopus 로고
    • Clinical impact of research on the podocyte slit diaphragm
    • Johnstone DB, Holzman LB. Clinical impact of research on the podocyte slit diaphragm. Nat Clin Pract Nephrol 2006; 2: 271-282.
    • (2006) Nat Clin Pract Nephrol , vol.2 , pp. 271-282
    • Johnstone, D.B.1    Holzman, L.B.2
  • 3
    • 84865788310 scopus 로고    scopus 로고
    • Signaling from the podocyte intercellular junction to the actin cytoskeleton
    • George B, Holzman LB. Signaling from the podocyte intercellular junction to the actin cytoskeleton. Semin Nephrol 2012; 32: 307-318.
    • (2012) Semin Nephrol , vol.32 , pp. 307-318
    • George, B.1    Holzman, L.B.2
  • 4
    • 18244384042 scopus 로고    scopus 로고
    • Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner
    • Asanuma K, Kim K, Oh J et al. Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. J Clin Invest 2005; 115: 1188-1198.
    • (2005) J Clin Invest , vol.115 , pp. 1188-1198
    • Asanuma, K.1    Kim, K.2    Oh, J.3
  • 5
    • 6344276685 scopus 로고    scopus 로고
    • Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization
    • Moeller MJ, Soofi A, Braun GS et al. Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization. EMBO J 2004; 23: 3769-3779.
    • (2004) EMBO J , vol.23 , pp. 3769-3779
    • Moeller, M.J.1    Soofi, A.2    Braun, G.S.3
  • 6
    • 22844436647 scopus 로고    scopus 로고
    • TRPC6 is a glomerular slit diaphragmassociated channel required for normal renal function
    • Reiser J, Polu KR, Moller CC et al. TRPC6 is a glomerular slit diaphragmassociated channel required for normal renal function. Nat Genet 2005; 37: 739-744.
    • (2005) Nat Genet , vol.37 , pp. 739-744
    • Reiser, J.1    Polu, K.R.2    Moller, C.C.3
  • 7
    • 33646401549 scopus 로고    scopus 로고
    • Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization
    • Verma R, Kovari I, Soofi A et al. Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization. J Clin Invest 2006; 116: 1346-1359.
    • (2006) J Clin Invest , vol.116 , pp. 1346-1359
    • Verma, R.1    Kovari, I.2    Soofi, A.3
  • 8
    • 33645746950 scopus 로고    scopus 로고
    • Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes
    • Jones N, Blasutig IM, Eremina V et al. Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature 2006; 440: 818-823.
    • (2006) Nature , vol.440 , pp. 818-823
    • Jones, N.1    Blasutig, I.M.2    Eremina, V.3
  • 9
    • 0037805606 scopus 로고    scopus 로고
    • Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis heterooligomers
    • Barletta GM, Kovari IA, Verma RK et al. Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis heterooligomers. J Biol Chem 2003; 278: 19266-19271.
    • (2003) J Biol Chem , vol.278 , pp. 19266-19271
    • Barletta, G.M.1    Kovari, I.A.2    Verma, R.K.3
  • 10
    • 0033529312 scopus 로고    scopus 로고
    • Nephrin is specifically located at the slit diaphragm of glomerular podocytes
    • Ruotsalainen V, Ljungberg P, Wartiovaara J et al. Nephrin is specifically located at the slit diaphragm of glomerular podocytes. Proc Natl Acad Sci USA 1999; 96: 7962-7967.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7962-7967
    • Ruotsalainen, V.1    Ljungberg, P.2    Wartiovaara, J.3
  • 11
    • 0037379340 scopus 로고    scopus 로고
    • Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1
    • Gerke P, Huber TB, Sellin L et al. Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1. J Am Soc Nephrol 2003; 14: 918-926.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 918-926
    • Gerke, P.1    Huber, T.B.2    Sellin, L.3
  • 12
    • 0032015551 scopus 로고    scopus 로고
    • Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome
    • Kestila M, Lenkkeri U, Mannikko M et al. Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephrotic syndrome. Mol Cell 1998; 1: 575-582.
    • (1998) Mol Cell , vol.1 , pp. 575-582
    • Kestila, M.1    Lenkkeri, U.2    Mannikko, M.3
  • 13
    • 84863066779 scopus 로고    scopus 로고
    • Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease
    • George B, Verma R, Soofi AA et al. Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease. J Clin Invest 2012; 122: 674-692.
    • (2012) J Clin Invest , vol.122 , pp. 674-692
    • George, B.1    Verma, R.2    Soofi, A.A.3
  • 14
    • 77949828806 scopus 로고    scopus 로고
    • Crk and CrkL adaptor proteins: Networks for physiological and pathological signaling
    • Birge RB, Kalodimos C, Inagaki F et al. Crk and CrkL adaptor proteins: networks for physiological and pathological signaling. Cell Commun Signal 2009; 7: 13.
    • (2009) Cell Commun Signal , vol.7 , pp. 13
    • Birge, R.B.1    Kalodimos, C.2    Inagaki, F.3
  • 15
    • 0035098436 scopus 로고    scopus 로고
    • Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome
    • Guris DL, Fantes J, Tara D et al. Mice lacking the homologue of the human 22q11.2 gene CRKL phenocopy neurocristopathies of DiGeorge syndrome. Nat Genet 2001; 27: 293-298.
    • (2001) Nat Genet , vol.27 , pp. 293-298
    • Guris, D.L.1    Fantes, J.2    Tara, D.3
  • 16
    • 33746970957 scopus 로고    scopus 로고
    • Cardiovascular and craniofacial defects in Crknull mice
    • Park TJ, Boyd K, Curran T. Cardiovascular and craniofacial defects in Crknull mice. Mol Cell Biol 2006; 26: 6272-6282.
    • (2006) Mol Cell Biol , vol.26 , pp. 6272-6282
    • Park, T.J.1    Boyd, K.2    Curran, T.3
  • 17
    • 78049434338 scopus 로고    scopus 로고
    • Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L
    • Hallock PT, Xu CF, Park TJ et al. Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L. Genes Dev 2010; 24: 2451-2461.
    • (2010) Genes Dev , vol.24 , pp. 2451-2461
    • Hallock, P.T.1    Xu, C.F.2    Park, T.J.3
  • 18
    • 58149379046 scopus 로고    scopus 로고
    • Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway
    • Park TJ, Curran T. Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway. J Neurosci 2008; 28: 13551-13562.
    • (2008) J Neurosci , vol.28 , pp. 13551-13562
    • Park, T.J.1    Curran, T.2
  • 19
    • 55049083860 scopus 로고    scopus 로고
    • A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors
    • Antoku S, Saksela K, Rivera GM et al. A crucial role in cell spreading for the interaction of Abl PxxP motifs with Crk and Nck adaptors. J Cell Sci 2008; 121: 3071-3082.
    • (2008) J Cell Sci , vol.121 , pp. 3071-3082
    • Antoku, S.1    Saksela, K.2    Rivera, G.M.3
  • 20
    • 0037769892 scopus 로고    scopus 로고
    • Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts
    • Lamorte L, Rodrigues S, Sangwan V et al. Crk associates with a multimolecular Paxillin/GIT2/beta-PIX complex and promotes Rac-dependent relocalization of Paxillin to focal contacts. Mol Biol Cell 2003; 14: 2818-2831.
    • (2003) Mol Biol Cell , vol.14 , pp. 2818-2831
    • Lamorte, L.1    Rodrigues, S.2    Sangwan, V.3
  • 21
    • 0036014939 scopus 로고    scopus 로고
    • Two gene fragments that direct podocyte-specific expression in transgenic mice
    • Moeller MJ, Sanden SK, Soofi A et al. Two gene fragments that direct podocyte-specific expression in transgenic mice. J Am Soc Nephrol 2002; 13: 1561-1567.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1561-1567
    • Moeller, M.J.1    Sanden, S.K.2    Soofi, A.3
  • 22
    • 0037247603 scopus 로고    scopus 로고
    • Podocyte-specific expression of cre recombinase in transgenic mice
    • Moeller MJ, Sanden SK, Soofi A et al. Podocyte-specific expression of cre recombinase in transgenic mice. Genesis 2003; 35: 39-42.
    • (2003) Genesis , vol.35 , pp. 39-42
    • Moeller, M.J.1    Sanden, S.K.2    Soofi, A.3
  • 23
    • 77954609124 scopus 로고    scopus 로고
    • Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture
    • Garg P, Verma R, Cook L et al. Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture. J Biol Chem 2010; 285: 22676-22688.
    • (2010) J Biol Chem , vol.285 , pp. 22676-22688
    • Garg, P.1    Verma, R.2    Cook, L.3
  • 24
    • 0141790220 scopus 로고    scopus 로고
    • Evaluation of a thick and thin section method for estimation of podocyte number, glomerular volume, and glomerular volume per podocyte in rat kidney with Wilms' tumor-1 protein used as a podocyte nuclear marker
    • Sanden SK, Wiggins JE, Goyal M et al. Evaluation of a thick and thin section method for estimation of podocyte number, glomerular volume, and glomerular volume per podocyte in rat kidney with Wilms' tumor-1 protein used as a podocyte nuclear marker. J Am Soc Nephrol 2003; 14: 2484-2493.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2484-2493
    • Sanden, S.K.1    Wiggins, J.E.2    Goyal, M.3
  • 25
    • 33845266145 scopus 로고    scopus 로고
    • The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal
    • Harkiolaki M, Gilbert RJ, Jones EY et al. The C-terminal SH3 domain of CRKL as a dynamic dimerization module transiently exposing a nuclear export signal. Structure 2006; 14: 1741-1753.
    • (2006) Structure , vol.14 , pp. 1741-1753
    • Harkiolaki, M.1    Gilbert, R.J.2    Jones, E.Y.3
  • 26
    • 79955716605 scopus 로고    scopus 로고
    • Neuronal polarization: The cytoskeleton leads the way
    • Stiess M, Bradke F. Neuronal polarization: the cytoskeleton leads the way. Dev Neurobiol 2011; 71: 430-444.
    • (2011) Dev Neurobiol , vol.71 , pp. 430-444
    • Stiess, M.1    Bradke, F.2
  • 27
    • 0033667398 scopus 로고    scopus 로고
    • F-actin fiber distribution in glomerular cells: Structural and functional implications
    • Cortes P, Mendez M, Riser BL et al. F-actin fiber distribution in glomerular cells: structural and functional implications. Kidney Int 2000; 58: 2452-2461.
    • (2000) Kidney Int , vol.58 , pp. 2452-2461
    • Cortes, P.1    Mendez, M.2    Riser, B.L.3
  • 28
    • 0031893246 scopus 로고    scopus 로고
    • A role of microtubules during the formation of cell processes in neuronal and non-neuronal cells
    • Kobayashi N, Mundel P. A role of microtubules during the formation of cell processes in neuronal and non-neuronal cells. Cell Tissue Res 1998; 291: 163-174.
    • (1998) Cell Tissue Res , vol.291 , pp. 163-174
    • Kobayashi, N.1    Mundel, P.2
  • 29
    • 46749093398 scopus 로고    scopus 로고
    • Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis
    • Matsuki T, Pramatarova A, Howell BW. Reduction of Crk and CrkL expression blocks reelin-induced dendritogenesis. J Cell Sci 2008; 121: 1869-1875.
    • (2008) J Cell Sci , vol.121 , pp. 1869-1875
    • Matsuki, T.1    Pramatarova, A.2    Howell, B.W.3
  • 30
    • 18744388826 scopus 로고    scopus 로고
    • Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules
    • Nakamura T, Komiya M, Sone K et al. Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules. Mol Cell Biol 2002; 22: 8721-8734.
    • (2002) Mol Cell Biol , vol.22 , pp. 8721-8734
    • Nakamura, T.1    Komiya, M.2    Sone, K.3
  • 31
    • 28844479472 scopus 로고    scopus 로고
    • The Cas family docking protein, HEF1, promotes the formation of neurite-like membrane extensions
    • Bargon SD, Gunning PW, O'Neill GM. The Cas family docking protein, HEF1, promotes the formation of neurite-like membrane extensions. Biochim Biophys Acta 2005; 1746: 143-154.
    • (2005) Biochim Biophys Acta , vol.1746 , pp. 143-154
    • Bargon, S.D.1    Gunning, P.W.2    O'Neill, G.M.3
  • 32
    • 0036189998 scopus 로고    scopus 로고
    • A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression
    • Saleem MA, O'Hare MJ, Reiser J et al. A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol 2002; 13: 630-638.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 630-638
    • Saleem, M.A.1    O'Hare, M.J.2    Reiser, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.