Snail1-dependent transcriptional repression of Cezanne2 in hepatocellular carcinoma

Oncogene

Volumn 33, Issue 22, 2014, Pages 2836-2845

  Xu, Z ^a,d   Pei, L ^a   Wang, L ^b   Zhang, F ^a   Hu, X ^c   Gui, Y ^c  

^a Department of Molecular Diagnosis ZhongCheng Translational Medicine Inc   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

Cezanne2; HCC; metastasis; Snail1

Indexed keywords

CEZANNE2; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; POLYUBIQUITIN; PROTEIN; TRANSCRIPTION FACTOR SNAIL; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CEZANNE2 GENE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UBIQUITINATION;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; ENDOPEPTIDASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; LIVER NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; NF-KAPPA B; PROTEIN BINDING; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; UBIQUITINATION;

EID: 84901855624     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.243     Document Type: Article

References (24)

1. Sun HC, Tang ZY. Angiogenesis in hepatocellular carcinoma: the retrospectives and perspectives. J Cancer Res Clin Oncol 2004; 130: 307-319.
2. Budhu A, Forgues M, Ye QH, Jia HL, He P, Zanetti KA et al. Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell 2006; 10: 99-111. (Pubitemid 44202603)
3. Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science 331: 1559-1564.
4. Doreau A, Belot A, Bastid J, Riche B, Trescol-Biemont MC, Ranchin B et al. Inter-leukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat Immunol 2009; 10: 778-785.
5. Shalom-Barak T, Quach J, Lotz M. Interleukin-17-induced gene expression in articular chondrocytes is associated with activation of mitogen-activated protein kinases and NF-kappaB. J Biol Chem 1998; 273: 27467-27473. (Pubitemid 28500465)
6. Xue J, Thippegowda PB, Hu G, Bachmaier K, Christman JW, Malik AB et al. NF-kappaB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-kappaB site in the ICAM-1 gene. Physiol Genomics 2009; 38: 42-53.
7. Astarci E, Sade A, Cimen I, Savas B, Banerjee S. The NF-kappaB target genes ICAM-1 and VCAM-1 are differentially regulated during spontaneous differentiation of Caco-2 cells. FEBS J 2012; 279: 2966-2986.
8. Bu W, Huang X, Tang Z. [The role of MMP-2 in the invasion and metastasis of hepatocellular carcinoma (HCC)]. Zhonghua Yi Xue Za Zhi 1997; 77: 661-664.
9. Kessenbrock K, Plaks V, Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 2010; 141: 52-67.
10. Yang P, Yuan W, He J, Wang J, Yu L, Jin X et al. Overexpression of EphA2, MMP-9, and MVD-CD34 in hepatocellular carcinoma: implications for tumor progression and prognosis. Hepatol Res 2009; 39: 1169-1177.
11. Evans PC, Smith TS, Lai MJ, Williams MG, Burke DF, Heyninck K et al. A novel type of deubiquitinating enzyme. J Biol Chem 2003; 278: 23180-23186. (Pubitemid 36830384)
12. Evans PC, Taylor ER, Coadwell J, Heyninck K, Beyaert R, Kilshaw PJ. Isolation and characterization of two novel A20-like proteins. Biochem J 2001; 357(Pt 3): 617-623. (Pubitemid 32735143)
13. Enesa K, Zakkar M, Chaudhury H, Luong le A, Rawlinson L, Mason JC et al. NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling. J Biol Chem 2008; 283: 7036-7045.
14. La Starza R, Crescenzi B, Pierini V, Romoli S, Gorello P, Brandimarte L et al. A common 93-kb duplicated DNA sequence at 1q21.2 in acute lymphoblastic leukemia and Burkitt lymphoma. Cancer Genet Cytogenet 2007; 175: 73-76. (Pubitemid 46694003)
15. Katzenellenbogen M, Pappo O, Barash H, Klopstock N, Mizrahi L, Olam D et al. Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice. Cancer Res 2006; 66: 4001-4010.
16. Khetchoumian K, Teletin M, Tisserand J, Mark M, Herquel B, Ignat M et al. Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha. Nat Genet 2007; 39: 1500-1506. (Pubitemid 350191338)
17. Nguyen H, Sankaran S, Dandekar S. Hepatitis C virus core protein induces expression of genes regulating immune evasion and anti-apoptosis in hepato-cytes. Virology 2006; 354: 58-68. (Pubitemid 44441506)
18. Tan C, Costello P, Sanghera J, Dominguez D, Baulida J, de Herreros AG et al. Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf- dependent transcription and expression of the E-cadherin repressor, snail, in APC-/-human colon carcinoma cells. Oncogene 2001; 20: 133-140. (Pubitemid 32142346)
19. Gotzmann J, Huber H, Thallinger C, Wolschek M, Jansen B, Schulte-Hermann R et al. Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness. J Cell Sci 2002; 115(Pt 6): 1189-1202. (Pubitemid 34272483)
20. Peinado H, Quintanilla M, Cano A. Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Biol Chem 2003; 278: 21113-21123. (Pubitemid 36806424)
21. de Herreros AG, Peiro S, Nassour M, Savagner P. Snail family regulation and epithelial mesenchymal transitions in breast cancer progression. J Mammary Gland Biol Neoplasia 2010; 15: 135-147.
22. Xu Z, Zheng Y, Zhu Y, Kong X, Hu L. Evidence for OTUD-6B participation in B lymphocytes cell cycle after cytokine stimulation. PLoS One 2011; 6: e14514.
23. Massoumi R, Kuphal S, Hellerbrand C, Haas B, Wild P, Spruss T et al. Down-regulation of CYLD expression by Snail promotes tumor progression in malignant melanoma. J Exp Med 2009; 206: 221-232.
24. Gao J, Huo L, Sun X, Liu M, Li D, Dong JT et al. The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration. J Biol Chem 2008; 283: 8802-8809.