Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle

Cell Cycle

Volumn 13, Issue 11, 2014, Pages 1756-1764

  Zhu, Yanting ^a   Zhou, Yuan ^a,b   Shi, Jue ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Anti mitotic drug; Apoptosis; DNA damage; Kinesin 5 inhibitor; Mitotic arrest; Mitotic slippage; Multinucleation; Paclitaxel

Indexed keywords

ADENOSINE TRIPHOSPHATASE INHIBITOR; ANTIMITOTIC AGENT; EMD 534085; KINESIN 5 INHIBITOR; PACLITAXEL; PROTEIN P53; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL LINE; CANCER COMBINATION CHEMOTHERAPY; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOLYSIS; DNA DAMAGE; DRUG CYTOTOXICITY; FEMALE; HCT116 CELL LINE; HELA CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MAMMAL CELL; MICROTUBULE; MITOSIS INHIBITION; MITOSIS SPINDLE; RNA INTERFERENCE; SINGLE CELL ANALYSIS; SURVIVAL RATE; WESTERN BLOTTING; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MITOSIS; NEOPLASMS; PROCEDURES; SPINDLE APPARATUS; TIME LAPSE IMAGING; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL MARKERS; CELL LINE, TUMOR; DNA DAMAGE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MICROTUBULES; MITOSIS; NEOPLASMS; PACLITAXEL; RNA INTERFERENCE; SINGLE-CELL ANALYSIS; SPINDLE APPARATUS; TIME-LAPSE IMAGING;

EID: 84901850093     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.28672     Document Type: Article

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