Autocrine IL-10 promotes human B-cell differentiation into IgM- or IgG-secreting plasmablasts

European Journal of Immunology

Volumn 44, Issue 6, 2014, Pages 1615-1621

  Heine, Guido ^a,b   Drozdenko, Gennadiy ^a   Grün, Joachim R ^b   Chang, Hyun Dong ^b   Radbruch, Andreas ^b   Worm, Margitta ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

Author keywords

Antibody secreting cell; Human B cells; IL 10; Transcriptome

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; CD20 ANTIGEN; CD38 ANTIGEN; CD40 ANTIGEN; CD5 ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN M; IMMUNOGLOBULIN MU CHAIN; INHIBITOR OF DIFFERENTIATION 3; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 21; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PROTEIN BCL 6; PROTEIN FOS; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 2; SUPPRESSOR OF CYTOKINE SIGNALING 3; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR PAX5;

ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; AUTOCRINE EFFECT; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; B LYMPHOCYTE DIFFERENTIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNITY; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; MEMORY CELL; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ANTIBODY-SECRETING CELL; HUMAN B CELLS; IL-10; TRANSCRIPTOME;

AUTOCRINE COMMUNICATION; CELL DIFFERENTIATION; FEMALE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOLOGIC MEMORY; INTERLEUKIN-10; MALE; PARACRINE COMMUNICATION; PLASMA CELLS; SIGNAL TRANSDUCTION;

EID: 84901832379     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343822     Document Type: Article

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