Accelerator-based BNCT

Neutron Capture Therapy: Principles and Applications

Volumn 9783642313349, Issue , 2012, Pages 41-54

  Kreiner, Andres J ^a,b,c  

^a CENTRO ATÓMICO CONSTITUYENTES   (Argentina)

^b UNIVERSIDAD NACIONAL DE SAN MARTÍN   (Argentina)

^c Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84901820412     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-31334-9_3     Document Type: Chapter

References (54)

1. Aleynik V et al (2011) BINP accelerator based epithermal neutron source. Appl Radiat Isot 69:1635-1638
2. Allen DA, Beynon TD (1995) A design study for an accelerator-based epithermal neutron beam for BNCT. Phys Med Biol 40:807-821
3. Anderson OA, Alpen EL, Kwan JW et al (1994) ESQ-focused 2.5 MeV DC accelerator for BNCT. In: Proceedings of the 4th European particle accelerator conference. London, 1994, pp 2619-2621
4. Bayanov BF, Belov VP, Bender ED et al (1998) Accelerator-based neutron sourcefor the neutron-capture and fast neutron therapy at hospital. Nucl Instrum Methods Phys Res A 413: 397-426
5. Bayanov B, Burdakov A, Chudaev et al (2008) First neutron generation in the BINP accelerator based neutron source. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 514-517
6. Bleuel DL, Donahue RJ, Ludewigt BA et al (1998) Designing accelerator-based epithermal neutron beams for BNCT. Med Phys 25:1725-1734.
7. Blue T, Yanch J (2003) Accelerator-based epithermal neutron sources for boron neutron capture therapy of brain tumors. J Neurooncol 62(1):19-31.
8. Burlon AA, Kreiner AJ (2008) A comparison between a TESQ accelerator and a reactor as a neutron sourcefor BNCT. Nucl Instrum Methods Phys Res B 266:763-771.
9. Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 458-461.
10. Burlon AA, Kreiner AJ, White SM et al (2001) In-phantom dosimetry using the 13 C(d, n) 14 N reaction for BNCT. Med Phys 28:796-803
11. Burlon AA, Kreiner AJ, Valda AA et al (2002) Optimization of a neutron production target and beam shaping assembly based on the 7 Li(p, n) 7 Be reaction. In: Research and development in neutron capture therapy. Monduzzi Editore, Bologna, pp 229-234
12. Burlon AA, Kreiner AJ et al (2004) An optimized neutron-beam shaping assembly for accelerator-based BNCT. Appl Radiat Isot 61:811
13. Burlon AA, Kreiner AJ, Valda AA et al (2005) Optimization of a neutron production target and a beam shaping assembly based on the 7Li(p, n) reaction for BNCT. Nucl Instrum Methods Phys Res B 229:144-156
14. Burlon AA, del V Roldan T, Kreiner AJ et al (2008) Nuclear reactions induced by deuterons and their applicability to skin tumor treatment through BNCT. Nucl Instrum Methods Phys Res B 266:4903-4910
15. Capoulat ME, Minsky DM, Kreiner AJ (2011) Applicability of the 9Be(d, n)10B reaction to AB-BNCT skin and deep tumor treatment. Appl Radiat Isot 69:1684-1687
16. Ceballos C et al (2011) Towards thefinal BSA modeling for the accelerator-driven BNCT facility at INFN LNL. Appl Radiat Isot 69:1660-1663
17. Cleland MR (2006) Industrial applications of electron accelerators. CAS Proc. Yellow reports CERN 2006-012:383-416
18. Colonna N, Beaulieu L, Phair L et al (1999) Measurements of low-energy (d, n) reactions for BNCT. Med Phys 26(5):793-798
19. Custodero S, Leung K, Mattioda F (2008) Feasibility study for the upgrade of a compact neutron generator for NCT application. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 450-453
20. Esposito J, Colautti P, Fabritsiev S et al (2008) Be target development for the accelerator-based SPES-BNCT facility at INFN Legnaro. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 466-469
21. Forton E, Stichelbaut F, Cambriani A et al (2008) Overview of the IBA accelerator-based BNCT system. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 530-534
22. Friedman A, Grote DP, Haber I (1992) Particle simulation of heavy ion fusion beams. Phys Fluids B 4:2203
23. Ganda F, Vujic J, Greenspan E et al (2008) Accelerator-driven sub-critical multiplier for BNCT. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 526-529
24. Ghani Z, Green S, Wojnecki et al (2008) BNCT beam monitoring, characterization and dosimetry. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 647-649.
25. Green S (1998) Developments in accelerator based BNCT. Radiat Phys Chem 51(4-6):561-569
26. Guzek J, Tapper U, McMurray W et al (1997) Characterization of the 9Be(d, n)10B reaction as a source of neutrons employing commercially available radiofrequency quadrupole (RFQ) linacs. In: Proceedings of SPIE, The International Society for Optical Engineering, 2867, pp 509-512
27. Halfon S, Paul M, Steinberg D et al (2008) High power accelerator-based BNC with a liquid Li target and new applications to treatment of infectious diseases. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 470-473.
28. Halfon S et al (2011) High power liquid-lithium target prototypefor accelerator-based boron neutron capture therapy. Appl Radiat Isot 69:1654-1656
29. Klinkowstein R, Shefer R, Yanch JC, et al (1997) Operation of a high current tandem electrostatic accelerator for boron neutron capture therapy. Advances in neutron capture therapy, Medicine and Physics, Elsevier Science B. V., Amsterdam, vol. 1, pp 522
30. Kobayashi T, Sakurai Y, Ono K (1998) Neutron irradiation systems for BNCT using accelerators and research reactors. Proc ECOMAP-98: 370-375
31. Kobayashi T, Bengua G, Tanaka K (2008) Neutrons for BNCT from the near threshold 7 Li(p, n) 7 Be on a thick Li target. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 478-481.
32. Kononov VN, Androsenko PA, Bohovko MV et al (1994) 7 Li(p, n) 7 Be reaction near the threshold: the prospective neutron sourcefor BNCT. In: Proceedings of the 1st international workshop on accelerator-based neutron sources for BNCT. vol 2, pp 477-483
33. Kononov et al (1996) Accelerator-based and intense directed neutron sourcefor BNCT. In: Conference proceedings, 7th international symposium on neutron capture therapy. vol 1, pp 528-532
34. Kononov VN, Bohovko MV, Kononov OE, et al (2006) Neutron therapy facility based on high current proton accelerator KG-2, 5. Proceedings of RuPAC, Novosibirsk, Russia, pp 118-119
35. Kreiner AJ, et al (eds) (2011a) Proceedings of the 14th international congress on neutron capture therapy. Appl Radiat Isot vol 69(12).
36. Kreiner AJ, Kwan JW, Burlon AA et al (2007) A tandem-electrostatic-quadrupolefor accelerator-based BNCT. Nucl Instrum Methods B 261:751-754
37. Kreiner AJ, Thatar Vento V, Levinas P et al (2008) Development of a Tandem-electrostaticquadrupole accelerator facility for BNCT. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 482-485
38. Kreiner AJ et al (2011) Development of a tandem-electrostatic-quadrupolefacility for accelerator-based boron neutron capture therapy. Appl Radiat Isot 69:1672-1675
39. Kwan JW, Ackerman GD, Chan CF et al (1995) Acceleration of 100 mA of H-in a single channel electrostatic quadrupole accelerator. Rev Sci Instrum 66(7):3864
40. Lee CL, Zhou XL (1999) Thick target neutron yields for the 7 Li(p, n) 7 Be reaction near threshold. Nucl Instrum Methods Phys Res B 152:1-11
41. Lee CL and Zhou XL (1999b) An algorithm for computing thick target differential p-Li neutron yields near threshold. In: Duggan JL et al (eds) Proceedings of the 15th international conference on the applications of accelerators in research and industry, pp 227-230
42. Levinas P, Kreiner AJ, Henestroza E (2008) Transport of high-intensity proton and deuteron beams through a TESQ accelerator. In: Proceedings of the 13th international congress on neutron capture therapy. ENEA, pp 411-414.
43. Liskien H, Paulsen A (1975) Neutron production cross section and energies for the reactions 7Li(p, n)7Be and 7Li(p, n)7Be. At Data Nucl Data Tables 15:57-84
44. Ludewigt BA, Chu WT, Donahue RJ et al (1997) An epithermal neutron sourcefor BNCT based on an ESQ-accelerator. LBNL report 40642
45. Minsky DM, Kreiner AJ, Valda AA (2011) AB-BNCT BSA based on the 7Li(p, n)7Be reaction optimization. Appl Radiat Isot 69:1668-1671
46. Pisent A, Colautti P, Esposito J et al (2006) Progress on the accelerator based SPES-BNCT project at INFN Legnaro. J Phys Conf Ser 41:391-399. doi: 10.1088/1742-6596/41/1/043.
47. Porter EH (1980) The statistics of dose/cure relationships for irradiated tumours. Part I. Br J Radiol 53:210
48. Tanaka H et al (2011) Experimental veri fi cation of beam characteristics for cyclotron-based epithermal neutron source (C-BENS). Appl Radiat Isot 69:1642-1645
49. Taskaev S, Bayanov B, Belov V et al (2006) Development of Li target for AB-BNCT. Advances in NCT. Neutrino, Osaka, pp 292-295
50. Vento VT et al (2011) Electrostatic design and beam transport for a folded tandem electrostatic quadrupole accelerator facility for accelerator-based boron neutron capture therapy. Appl Radiat Isot 69:1649-1653
51. Wheeler F, Nigg D, Capala J et al (1999) BNCT: implications of neutron beam and boron compound characteristics. Med Phys 26(7):1237-1244
52. Yanch JC, Zhou X-I, Shefer RE et al (1992) Accelerator-based epithermal neutron beam design for NCT. Med Phys 19:709-721.
53. Ziegler JF (2008) The stopping and range of ions in matter. www.srim.org/SRIM/SRIM2008. htm. Accessed 2009
54. Zonta A et al (eds) (2008) BNCT: a new option against cancer. Proceedings of the 13th international congress on neutron capture therapy, Appl Radiat Isot. Florence, Italy, 67(7-8): s1-s380