A comparison between a TESQ accelerator and a reactor as a neutron sources for BNCT

Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

Volumn 266, Issue 5, 2008, Pages 763-771

  Burlon, A A ^a,b   Kreiner, A J ^a,b,c  

^a DEPARTAMENTO DE FÍSICA   (Argentina)

^b UNIVERSIDAD NACIONAL DE SAN MARTÍN   (Argentina)

^c Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

87.56. v; 87.56.By; 87.64.Aa; 87.80. y; 7Li(p,n)7Be reaction; Accelerator based boron neutron capture therapy (AB BNCT); MCNP simulations; Reactor based BCNT; Tandem electrostatic quadrupole accelerator

Indexed keywords

COMPUTER SIMULATION; FISSION REACTIONS; FLUORINE COMPOUNDS; NEUTRON SOURCES; NUCLEAR REACTORS;

ACCELERATOR-BASED BORON NEUTRON CAPTURE THERAPY; BNCT; MCNP SIMULATIONS; TESQ ACCELERATORS;

PARTICLE ACCELERATORS;

EID: 40949132463     PISSN: 0168583X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nimb.2008.01.004     Document Type: Article

References (20)

1. Harling O.K., Riley K.J., Binns P.J., Patel H., and Coderre J.A. The MIT user center for neutron capture therapy research. Radiat. Res. 164 (2005) 221
2. B.M. Roth, M.R. Bonomi, S.J. González, R. Jiménez Rebagliati et al., BNCT clinical trials of skin melanoma patients in Argentina, in: Y. Nakagawa, T. Kobayashi, H. Fukuda (Eds.), Advances in Neutron Capture Therapy, Proceedings of ICNCT-12, Kagawa, Japan, 2006, p. 14.
3. I. Kato, K. Ono, Y. Sakurai, M. Ohmae, A. Kamida, Y. Fujita et al., Boron neutron capture therapy for recurrent head and neck malignancies, in: Y. Nakagawa, T. Kobayashi, H. Fukuda (Eds.), Advances in Neutron Capture Therapy, Proceedings of ICNCT-12, Kagawa, Japan, 2006, p. 1.
4. J. Capala, K. Sköld, B-H. Stemstan, P. M. Munck af Rosenschöld, et al., Clinical BNCT studies in Sweden, in: W. Sauerwein, R. Moss, A. Wittig (Eds.), Research and Development in Neutron Capture Therapy, Proceedings of the 10 ICNCT, Essen, Germany, Moduzzi Ed., Bologna, 2002, p. 1101.
5. A. Wittig, K. Hideghéty, P. Paquis, J. Heimans, et al., Current clinical results of the EORTC-Study 11961, in: W. Sauerwein, R. Moss, A. Wittig (Eds.), Research and Development in Neutron Capture Therapy, Proceedings of the 10 ICNCT, Essen, Germany, Moduzzi Ed., Bologna, 2002, p. 1117.
6. Kreiner A.J., Kwan J.W., Burlon A.A., Di Paolo H., Henestroza E., Minsky D.M., Valda A.A., Debray M.E., and Somacal H.R. Tandem-ESQ for accelerator-based BNCT. Nucl. Instr. and Meth. B 261 (2007) 751
7. Blue T.E., and Yanch J.C. Accelerator-based epithermal neutron sources for boron neutron capture therapy of brain tumors. J. Neuro-Oncol. 62 1 (2003) 19
8. Riley K.J., Binns P.J., and Harling O.K. Performance characteristics of the MIT fission converter based epithermal neutron beam. Phys. Med. Biol. 48 (2003) 943
9. 6Li Filtration. Int. J. Radiat. Oncol. Biol. Phys. 67 5 (2007) 1484
10. J.F. Briesmeister, A general Monte Carlo n-particle transport code, Los Alamos National Laboratory, Los Alamos, NM, USA, 2000.
11. 7Be reaction for BNCT. Nucl. Instr. and Meth. B 229 (2005) 144
12. Auterinen I., Serén T., Anttila K., Kosunen A., and Savolainen S. Measurement of free beam neutron spectra at eight BNCT facilities worldwide. Nucl. Appl. Radiat. Isotop. 61 5 (2004) 1021
13. 7Be reaction near threshold. Nucl. Instr. and Meth. B 152 (1999) 1
14. W. Snyder, M. Ford, G. Warner, H. Fischer, Estimates of absorbed fractions for monoenergetic photon source uniformly distributed in various organs of a heterogeneous phantom, Medical Internal Radiation Dose Committee (MIRD) Pamphlet No. 5, Supplement No. 3, J. Nucl. Med. 10 (1969).
15. Brooks R.A., Dichiro G., and Keller M.R. Explanation of cerebral white-grey contrast in computer tomography. J. Comput. Assist. Tomogr. 4 (1980) 489
16. Coderre J.A., Makar M.S., and Micca P.L. Derivations of relatives biological effectiveness for the high-LET radiations produced during boron neutron capture irradiations of the 9L rat gliosarcoma in-vivo. Int. J. Radiat. Oncol. Biol. Phys. 27 (1993) 1121
17. Marek M., and Viererbl L. Spatial characterization of BNCT beams. Appl. Radiat. Isotop. 61 5 (2004) 1051
18. D.L. Bleuel, R.J. Donahue, B.A. Ludewigt, J. Vujic, Development of a neutron energy-biased in-air figure of merit for predicting in-phantom bnct neutron beam characteristics, in: Proceeding of the eighth International Symposium on Neutron Capture Therapy for Cancer, La Jolla, California, USA, 1998, p. 13.
19. Laramore G.E., Wheeler F.J., Wessol D.E., Stelzer K.J., and Griffin T.W. A BNCT tumor control curve for malignant glioma from fast neutron radiotherapy data: implications for beam delivery and compound selection. In: Larsson B., Crawford J., and Weinreich R. (Eds). Advances in Neutron Capture Therapy, Proceedings of the Seventh International Symposium on Neutron Capture Therapy for Cancer (1997), Elsevier Science, Amsterdam
20. Wheeler F., Nigg D., Capala J., Watkins P., Vroegindeweij C., Auterinen I., Seppala T., and Bleuel D. BNCT: implications of neutron beam and boron compound characteristics. Med. Phys. 26 7 (1999) 1237