The PDZ-binding motif of the avian NS1 protein affects transmission of the 2009 influenza A(H1N1) virus

Biochemical and Biophysical Research Communications

Volumn 449, Issue 1, 2014, Pages 19-25

  Kim, Jin Il ^a,b   Hwang, Min Woong ^a,b   Lee, Ilseob ^a,b   Park, Sehee ^a,b   Lee, Sangmoo ^a,b   Bae, Joon Yong ^a,b   Heo, Jun ^b   Kim, Donghwan ^b   Jang, Seok Il ^b   Park, Mee Sook ^a,b   Kwon, Hyung Joo ^b   Song, Jin Won ^a   Park, Man Seong ^a,b  

^a Korea University College of Medicine   (South Korea)

^b Hallym University   (South Korea)

Author keywords

Influenza A virus; Interferon; NS1 protein; PDZ binding motif; Transmission

Indexed keywords

INTERFERON; NONSTRUCTURAL PROTEIN 1;

2009 H1N1 INFLUENZA; ANIMAL CELL; ARTICLE; FEMALE; GUINEA PIG; INFLUENZA VIRUS A H5N1; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN MOTIF; VIRUS REPLICATION; VIRUS TRANSMISSION; VIRUS VIRULENCE;

AVES; CAVIA; INFLUENZA A VIRUS; MUS;

INFLUENZA A VIRUS; INTERFERON; NS1 PROTEIN; PDZ-BINDING MOTIF; TRANSMISSION;

ANIMALS; BIRDS; FEMALE; GUINEA PIGS; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; MICE; MICE, INBRED BALB C; PDZ DOMAINS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL NONSTRUCTURAL PROTEINS; VIRUS ACTIVATION; VIRUS REPLICATION;

EID: 84901818136     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.04.132     Document Type: Article

References (32)

1. P. Palese, and M.L. Shaw Orthomyxoviridae: The viruses and their replication D.M. Knipe, P.M. Howley, Fields virology 5th ed. 2007 Lippincott Williams & Wilkins
2. Y. Muramoto, T. Noda, E. Kawakami, R. Akkina, and Y. Kawaoka Identification of novel influenza A virus proteins translated from PA mRNA J. Virol. 87 2013 2455 2462
3. C. Brockwell-Staats, R.G. Webster, and R.J. Webby Diversity of influenza viruses in swine and the emergence of a novel human pandemic influenza A (H1N1) Influenza Other Respir. Viruses 3 2009 207 213
4. J.I. Kim, I. Lee, S. Park, S. Lee, M.W. Hwang, J.Y. Bae, J. Heo, D. Kim, S.I. Jang, K. Kim, and M.S. Park Phylogenetic analysis of a swine influenza A(H3N2) virus isolated in Korea in 2012 PLoS ONE 9 2014 e88782
5. P.F. Wright, G. Neumann, and Y. Kawaoka Orthomyxoviruses D.M. Knipe, P.M. Howley, Fields virology 5th ed. 2007 Lippincott Williams & Wilkins
6. D.A. Engel The influenza virus NS1 protein as a therapeutic target Antiviral Res. 99 3 2013 409 416
7. Y. Kawaoka, O.T. Gorman, T. Ito, K. Wells, R.O. Donis, M.R. Castrucci, I. Donatelli, and R.G. Webster Influence of host species on the evolution of the nonstructural (NS) gene of influenza A viruses Virus Res. 55 1998 143 156 (Pubitemid 28345169)
8. B.G. Hale, R.E. Randall, J. Ortin, and D. Jackson The multifunctional NS1 protein of influenza A viruses J. Gen. Virol. 89 2008 2359 2376
9. A. Garcia-Sastre, A. Egorov, D. Matassov, S. Brandt, D.E. Levy, J.E. Durbin, P. Palese, and T. Muster Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems Virology 252 1998 324 330 (Pubitemid 29013414)
10. A. Garcia-Sastre, R.K. Durbin, H. Zheng, P. Palese, R. Gertner, D.E. Levy, and J.E. Durbin The role of interferon in influenza virus tissue tropism J. Virol. 72 1998 8550 8558 (Pubitemid 28471792)
11. S. Boulo, H. Akarsu, R.W. Ruigrok, and F. Baudin Nuclear traffic of influenza virus proteins and ribonucleoprotein complexes Virus Res. 124 2007 12 21 (Pubitemid 46216557)
12. R.A. Lamb, and C.J. Lai Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virus Cell 21 1980 475 485 (Pubitemid 10047101)
13. W.G. Dundon, and I. Capua A Closer Look at the NS1 of Influenza Virus Viruses 1 2009 1057 1072
14. Z.A. Bornholdt, and B.V. Prasad X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus Nature 456 2008 985 988
15. J.C. Obenauer, J. Denson, P.K. Mehta, X. Su, S. Mukatira, D.B. Finkelstein, X. Xu, J. Wang, J. Ma, Y. Fan, K.M. Rakestraw, R.G. Webster, E. Hoffmann, S. Krauss, J. Zheng, Z. Zhang, and C.W. Naeve Large-scale sequence analysis of avian influenza isolates Science 311 2006 1576 1580
16. J.X. Long, D.X. Peng, Y.L. Liu, Y.T. Wu, and X.F. Liu Virulence of H5N1 avian influenza virus enhanced by a 15-nucleotide deletion in the viral nonstructural gene Virus Genes 36 2008 471 478
17. D. Jackson, M.J. Hossain, D. Hickman, D.R. Perez, and R.A. Lamb A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity Proc. Natl. Acad. Sci. U.S.A. 105 2008 4381 4386 (Pubitemid 351754389)
18. S.M. Soubies, T.W. Hoffmann, G. Croville, T. Larcher, M. Ledevin, D. Soubieux, P. Quere, J.L. Guerin, D. Marc, and R. Volmer Deletion of the C-terminal ESEV domain of NS1 does not affect the replication of a low-pathogenic avian influenza virus H7N1 in ducks and chickens J. Gen. Virol. 94 2013 50 58
19. B.G. Hale, J. Steel, B. Manicassamy, J. Ye, D. Hickman, A.C. Lowen, D.R. Perez, and A. Garcia-Sastre Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus J. Gen. Virol. 91 2010 1737 1742
20. E. Hoffmann, G. Neumann, Y. Kawaoka, G. Hobom, and R.G. Webster A DNA transfection system for generation of influenza A virus from eight plasmids Proc. Natl. Acad. Sci. U.S.A. 97 2000 6108 6113 (Pubitemid 30367531)
21. J.I. Kim, I. Lee, S. Park, and M.S. Park Surface glycoproteins determine the feature of the 2009 pandemic H1N1 virus BMB Rep. 45 2012 2009 653 658
22. A. Rambaut, O.G. Pybus, M.I. Nelson, C. Viboud, J.K. Taubenberger, and E.C. Holmes The genomic and epidemiological dynamics of human influenza A virus Nature 453 2008 615 619 (Pubitemid 351769300)
23. G. Neumann, H. Chen, G.F. Gao, Y. Shu, and Y. Kawaoka H5N1 influenza viruses: outbreaks and biological properties Cell Res. 20 2010 51 61
24. C. Seitz, T. Frensing, D. Hoper, G. Kochs, and U. Reichl High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state J. Gen. Virol. 91 2010 1754 1763
25. H. Shelton, M. Smith, L. Hartgroves, P. Stilwell, K. Roberts, B. Johnson, and W. Barclay An influenza reassortant with polymerase of pH1N1 and NS gene of H3N2 influenza A virus is attenuated in vivo J. Gen. Virol. 93 2012 998 1006
26. S.G. Van Poucke, J.M. Nicholls, H.J. Nauwynck, and K. Van Reeth Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distribution Virol. J. 7 2010 38
27. G. Neumann, and Y. Kawaoka The first influenza pandemic of the new millennium Influenza Other Respir. Viruses 5 2011 157 166
28. M.S. Park, M.L. Shaw, J. Munoz-Jordan, J.F. Cros, T. Nakaya, N. Bouvier, P. Palese, A. Garcia-Sastre, and C.F. Basler Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins J. Virol. 77 2003 1501 1511 (Pubitemid 36055570)
29. J. Desmyter, J.L. Melnick, and W.E. Rawls Defectiveness of interferon production and of rubella virus interference in a line of African green monkey kidney cells (Vero) J. Virol. 2 1968 955 961
30. A. Hayman, S. Comely, A. Lackenby, L.C. Hartgroves, S. Goodbourn, J.W. McCauley, and W.S. Barclay NS1 proteins of avian influenza A viruses can act as antagonists of the human alpha/beta interferon response J. Virol. 81 2007 2318 2327
31. J. Talon, C.M. Horvath, R. Polley, C.F. Basler, T. Muster, P. Palese, and A. Garcia-Sastre Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein J. Virol. 74 2000 7989 7996 (Pubitemid 30641643)
32. J.I. Kim, I. Lee, S. Park, M.W. Hwang, J.Y. Bae, S. Lee, J. Heo, M.S. Park, and A. Garcia-Sastre Genetic requirement for hemagglutinin glycosylation and its implications for influenza A H1N1 virus evolution J. Virol. 87 2013 7539 7549