Human neural stem cells survive long term in the midbrain of dopamine-depleted monkeys after GDNF overexpression and project neurites toward an appropriate target

Stem Cells Translational Medicine

Volumn 3, Issue 6, 2014, Pages 692-701

  Wakeman, Dustin R ^a,b,c   Redmond Jr , D Eugene ^d   Dodiya, Hemraj B ^c   Sladek Jr , John R ^e   Leranth, Csaba ^d   Teng, Yang D ^f   Jude Samulski, R ^g   Snyder, Evan Y ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BURNHAM INSTITUTE   (United States)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

GDNF; MPTP; Neural stem cells; Parkinson; Primate; Stem cell; Transplantation

Indexed keywords

DOPAMINE; FLUOROGOLD; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; PARVOVIRUS VECTOR; TYROSINE 3 MONOOXYGENASE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NERVE GRAFT; NEURAL STEM CELL; NEURITE; NONHUMAN; PARKINSON DISEASE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA; WESTERN BLOTTING;

GDNF; MPTP; NEURAL STEM CELLS; PARKINSON; PRIMATE; STEM CELL; TRANSPLANTATION;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; CELL LINE; CELL LINEAGE; CELL SHAPE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; GENETIC THERAPY; GENETIC VECTORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HUMANS; MESENCEPHALON; MPTP POISONING; NEURAL STEM CELLS; NEURITES; NEUROGENESIS; REGENERATIVE MEDICINE; STEM CELL NICHE; TIME FACTORS; TRANSDUCTION, GENETIC; TRANSFECTION; UP-REGULATION;

EID: 84901815350     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2013-0208     Document Type: Article

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