Proteolipid protein gene product can be secreted and exhibit biological activity during early development

Journal of Neuroscience

Volumn 19, Issue 6, 1999, Pages 2143-2151

  Yamada, Masahisa ^a   Ivanova, Anna ^b   Yamaguchi, Yoshihide ^a   Lees, Marjorie B ^a   Ikenaka, Kazuhiro ^b  

^a NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Cell culture; Differentiation factor; DM20; Myelin; Myelin proteolipid protein; Oligodendrocyte development

Indexed keywords

BROXURIDINE; GENE PRODUCT; PROTEOLIPID PROTEIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL POPULATION; CONTROLLED STUDY; EXPERIMENTAL MODEL; GLIA CELL; MOUSE; MYELINATION; NERVE CELL; NERVE CELL INHIBITION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN SECRETION; PROTEIN STRUCTURE;

EID: 0033559470     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-06-02143.1999     Document Type: Article

References (42)

1. Asakura K, Hunter SF, Rodriguez M (1997) Effects of transforming growth factor-β and platelet derived growth factor on oligodendrocyte precursors: insights gained from a neuronal cell line. J Neurochem 68:2281-2290.
2. Bansal R, Warrington AE. Gard AL, Ranscht B, Pfeiffer SE (1989) Multiple and novel specificities of monoclonal antibodies O1, O4, and R-mAb used in the analysis of oligodendrocyte development. J Neurosci Res 4:548-557.
3. Bartlett WF. Knapp PE, Skoff RP (1988) Glial conditioned medium enables jimpy oligodendrocyte to express properties of normal oligodendrocytes: production of myelin antigens and membranes. Glia 1:253-259.
4. Boison D, Stoffel W (1994) Disruption of the compacted myelin sheath of axon of the central nervous system in proteolipid protein-deficient mice. Proc Natl Acad Sci USA 91:11709-11713.
5. Boison D, Bussow H, D'Urso D.Müller H-W, Stoffel W (1995) Adhesive properties of proteolipid protein are responsible for the compaction of CNS myelin sheaths. J Neurosci 15:5502-5513.
6. Bottenstein JE, Hunter SF, Seidel M (1988) CNS neuronal cell line-derived factors regulated gliogenesis in neonatal rat brain cultures. J Neurosci Res 20:291-303.
7. Gonye GE, Warrington AE, DeVito JA, Pfeiffer SE (1994) Oligodendrocyte precursor quantitation and localization in perinatal brain using a retrospective bioassay. J Neurosci 14:5365-5372.
8. Gow A, Friedrich Jr VL, Lazzarini RA (1994) Many naturally occurring mutations of myelin proteolipid protein impair its intracellular transport. J Neurosci Res 37:574-583.
9. Gow A, Gragerov A, Gard A, Colman DR, Lazzarini RA (1997) Conservation of topology, but not conformation, of the proteolipid proteins of the myelin sheath. J Neurosci 17:181-189.
10. Hardy RJ, Friedrich VL (1996) Oligodendrocyte progenitors re generated throughout the embryonic mouse brain, but differentiated in restricted foci. Development 122:2059-2069.
11. Hu F. Lesney PF (1964) The isolation and cytology of two pigment cell strains from B16 mouse melanomas. Cancer Res 24:1634-1643.
12. Hudson LD, Nadon NL (1992) Amino acid substitutions in proteolipid protein that cause dysmyelination. In: Myelin: biology and chemistry (Martenson RE, ed), pp 677-702. Boca Raton, FL: CRC.
13. Hunter SF, Bottenstcin JE (1989) Bipotential glial progenitors are targets of neuronal cell line-derived growth factors. Dev Brain Res 49:33-49.
14. Hunter SF, Bottenstein JE (1991) O-2A glial progenitors from mature brain respond to CNS neural cell line-derived growth factors. J Neurosci Res 28:574-582.
15. Ikenaka K, Kagawa T, Mikoshiba K (1992) Selective expression of DM20, an alternatively spliced myelin proteolipid protein gene product, in developing nervous system and in nonglial cells. J Neurochem 58:2248-2253.
16. Jung M, Sommer I, Schachner M, Nave K-A (1996) Monoclonal antibody O10 defines a conformationally sensitive cell-surface epitope of proteolipid protein (PLP): evidence that PLP misfolding underlies dysmyelination in mutant mice. J Neurosci 16:7920-7929.
17. Kagawa T, Ikenaka K. Inoue Y, Kuriyama S, Tsujii T, Nakao J, Nakajima K, Aruga J, Okano H, Mikoshiba K ( 1994) Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene. Neuron 13:427-442.
18. Kitagawa K, Sinoway MP, Yang C, Could RM, Colman DR (1993) A proteolipid protein gene family: expression in sharks and rays and possible evolution from an ancestral gene encoding a pore-forming polypeptide. Neuron 11:433-448.
19. Klugmann M, Schwab M H, Pühlhofer A, Schneider A, Zimmeremann F, Griffiths IR, Nave K-A (1997) Assembly of CNS myelin in the absence of proteolipid protein. Neuron 18:59-70.
20. Knapp PE (1996) Proteolipid protein: is it more than just a structural component of myelin? Dev Neurosci 18:297-308.
21. Knapp PE, Skoff RP, Benjamins JA, Studzinski DM (1992) Oligodendrocytes from hypomyelinated jirnpy mice synthesize an altered PLP in vitro. Trans Am Soc Neurochem 23:134.
22. Lachapelle F, Lapie P, Campagnoni AT, Gumpel M (1991) Oligodendrocytes of jimpy phenotype can be partially restored by environmental factors in vivo. J Neurosci Res 29:235-243.
23. Levine SP, Wong D, Macklin WB (1990) Developmental expression of proteolipid protein and DM20 mRNAs and proteins in the rat brain. Dev Neurosci 12:235-250.
24. Mikoshiba K, Okano H, Tamura T, Ikenaka K (1991) Structure and function of myelin protein gene. Annu Rev Neurosci 14:201-217.
25. Monreal J (1975) Chromatographic fraction of brain white matter proteolipid. J Neurochem 24:539-541.
26. Moriguchi A, Ikenaka K, Furuichi T, Okano H, Iwasaki Y, Mikoshiba K (1987) The fifth exon of the myelin proteolipid protein-coding gene is not utilized in the brain of jimpy mutant mice. Gene 55:333-337.
27. Nakao J, Yamada M, Kagawa T, Kim SU, Miyao Y, Shimizu K, Mikoshiba K, Ikenaka K (1995) Expression of proteolipid protein gene is directly associated with secretion of a factor influencing oligodendrocyte development. J Neurochem 64:2396-2403.
28. Nave K-A, Lai C, Bloom FE, Milner RJ (1986) Jimpy mutant mouse: a 74 base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing. Proc Natl Acad Sci USA 83:9264-9268.
29. Nixon RA (1982) Increased axonal proteolysis in myelin-deficient mutant mice. Science 215:999-1001.
30. Okano H, Masayuki M, Moriguchi A, Ikenaka K, Tsukada Y, Mikoshiba K (1987) Inefficient transcription of the myelin basic protein gene possibly causes hypomyelination in myelin-deficient mutant mice. J Neurochem 48:470-476.
31. Readhead C, Schneider A, Griffiths I, Nave K-A (1994) Premature arrest of myelin formation in transgenic mice with increased proteolipid protein gene dosage. Neuron 12:583-595.
32. Schneider A, Griffiths IR, Readhead C, Nave K-A (1995) Dominant-negative action of the jimpy mutation in mice complemented with an autosomal transgene for myelin proteolipid protein. Proc Natl Acad Sci USA 92:4447-4451.
33. Schubert D, Carlisle W, Look C (1975) Putative neurotransmitters in clonal cell lines. Nature 254:341-343.
34. Skoff RP (1976) Myelin deficit in thcjimpy mouse maybe due to cellular abnormalities in astroglia. Nature 264:560-562.
35. Skoff RP. Knapp PE (1992) Phenotypic expression of X-linked genetic defects affecting myclination. In Myelin: biology and chemistry (Martcnson RE, ed), pp 653-676. Boca Raton. FL: CRC.
36. Sommer I. Schachncr M (1981) Monoclonal antibodies (O1 to O4) to oligodcndrocyte cell surfaces: an immunocytological study in ihc central nervous system. Dev Biol 83:311-327.
37. Sundarraj N, Schachner M, Pfeifer SE (1975) Biochemically differentiated mouse glial lines carrying a nervous system specific cell surface antigen (NS-1). Proc Natl Acad Sci USA 72: 1927-1931.
38. Timsit S, Bally-Cuif L, Colman DR. Zalc B (1992) DM20 mRNA is expressed during the embryonic development of the nervous syslem of the mouse. J Neurochem 58:1172-1175.
39. Timsit S, Martincz S, Allinquant B, Peyron F. Puelles L, Zalc B (1995) Oligodendrocyles originale in a restricted zone of the embryonic ventral neural tube defined by DM20 mRNA expression. J Neurosci 15:1012-1024.
40. Weimbs T, Stoffel W (1992) Protcolipid protein (PLP) of CNS myclin: positions of free, disulfide-bonded. and fatty acid thioestcr-linked cysteinc residues and implications for the membrane topology of PLP. Biochemistry 31:12289-12296.
41. Yamaguchi Y. Ikenaka K, Niinobe M, Yamada H, Mikoshiba K (1996) Myelin proteolipid protein (PLP), but not DM20. is an inositol hexakisphosphate-binding protein. J Biol Chern 271:27838-27846.
42. Yamamura T, Konola JT. Wekerle H, Lees MB (1991) Monoclonal antibodies against myelin proteolipid protein: identification and characterization of two major determinants. J Neurochem 57:1671-1680.