Abnormalities in airway epithelial junction formation in chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 189, Issue 11, 2014, Pages 1439-1442

  Heijink, Irene H ^a   Noordhoek, Jacobien A ^a   Timens, Wim ^a   Van Oosterhout, Antoon J M ^a   Postma, Dirkje S ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; CYTOKERATIN 18; CYTOKERATIN 5; OCCLUDIN; PROTEIN P63; PROTEIN ZO1;

BRONCHUS MUCOSA; BRUSH BORDER; CELL CONTACT; CELL DIFFERENTIATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CORTICOSTEROID THERAPY; ELECTRIC RESISTANCE; GRAFT RECIPIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; LETTER; LUNG ALVEOLUS EPITHELIUM; LUNG FUNCTION; ORGAN DONOR; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY TRACT INFLAMMATION; SMOKING; SMOKING CESSATION; TIGHT JUNCTION; WESTERN BLOTTING;

ADULT; AGED; DOWN-REGULATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; RISK FACTORS; RNA, MESSENGER; SMOKING;

EID: 84901765524     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201311-1982LE     Document Type: Letter

References (17)

1. Holgate ST. Epithelium dysfunction in asthma. J Allergy Clin Immunol 2007;120:1233-1244, quiz 1245-1246.
2. Shaykhiev R, Otaki F, Bonsu P, Dang DT, Teater M, Strulovici-Barel Y, Salit J, Harvey BG, Crystal RG. Cigarette smoking reprograms apical junctional complex molecular architecture in the human airway epithelium in vivo. Cell Mol Life Sci 2011;68:877-892.
3. Milara J, Peiró T, Serrano A, Cortijo J. Epithelial to mesenchymal transition is increased in patients with COPD and induced by cigarette smoke. Thorax 2013;68:410-420.
4. Hogg JC. Bronchial mucosal permeability and its relationship to airways hyperreactivity. Eur J Respir Dis Suppl 1982;122:17-22. (Pubitemid 13235834)
5. Heijink IH, Brandenburg SM, Postma DS, van Oosterhout AJ. Cigarette smoke impairs airway epithelial barrier function and cell -cell contact recovery. Eur Respir J 2012;39:419-428.
6. van den Berge M, Steiling K, Timens W, Hiemstra PS, Sterk PJ, Heijink IH, Liu G, Alekseyev YO, Lenburg ME, Spira A, et al. Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity. Thorax 2014;69:14-23.
7. Hackett TL, Shaheen F, Johnson A, Wadsworth S, Pechkovsky DV, Jacoby DB, Kicic A, Stick SM, Knight DA. Characterization of side population cells from human airway epithelium. Stem Cells 2008;26:2576-2585.
8. Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS; GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 2001;163:1256-1276. (Pubitemid 32378468)
9. Heijink IH, Postma DS, Noordhoek JA, Broekema M, Kapus A. House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium. Am J Respir Cell Mol Biol 2010;42:69-79.
10. Heijink IH, Brandenburg SM, Noordhoek JA, Postma DS, Slebos DJ, van Oosterhout AJ. Characterisation of cell adhesion in airway epithelial cell types using electric cell-substrate impedance sensing. Eur Respir J 2010;35:894-903.
11. Wegener J, Keese CR, Giaever I. Electric cell- substrate impedance sensing (ECIS) as a noninvasive means to monitor the kinetics of cell spreading to artificial surfaces. Exp Cell Res 2000;259:158-166.
12. Xiao C, Puddicombe SM, Field S, Haywood J, Broughton-Head V, Puxeddu I, Haitchi HM, Vernon-Wilson E, Sammut D, Bedke N, et al. Defective epithelial barrier function in asthma. J Allergy Clin Immunol 2011;128:549-556, e1-e12.
13. Heijink I, van Oosterhout A, Kliphuis N, Jonker M, Hoffmann R, Telenga E, Klooster K, Slebos DJ, ten Hacken N, Postma D, et al. Oxidant-induced corticosteroid unresponsiveness in human bronchial epithelial cells. Thorax 2014;69:5-13.
14. Hackett TL, Singhera GK, Shaheen F, Hayden P, Jackson GR, Hegele RG, Van ES, Bai TR, Dorscheid DR, Knight DA. Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to RSV and air pollution. Am J Respir Cell Mol Biol 2011;45:1090-1100.
15. Kubota H, Chiba H, Takakuwa Y, Osanai M, Tobioka H, Kohama G, Mori M, Sawada N. Retinoid X receptor a and retinoic acid receptor g mediate expression of genes encoding tight-junction proteins and barrier function in F9 cells during visceral endodermal differentiation. Exp Cell Res 2001;263:163-172. (Pubitemid 32989116)
16. Dragsten PR, Handler JS, Blumenthal R. Asymmetry in epithelial cells: is the tight junction a barrier to lateral diffusion in the plasma membrane? Prog Clin Biol Res 1982;91:525-536.
17. Sethi S, Murphy TF. Infection in the pathogenesis and course of chronic obstructive pulmonary disease. N Engl J Med 2008;359:2355-2365.