Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

Thorax

Volumn 69, Issue 1, 2014, Pages 14-23

  Van Den Berge, Maarten ^a   Steiling, Katrina ^b   Timens, Wim ^a   Hiemstra, Pieter S ^c   Sterk, Peter J ^d   Heijink, Irene H ^a   Liu, Gang ^b   Alekseyev, Yuriy O ^b   Lenburg, Marc E ^b   Spira, Avrum ^b   Postma, Dirkje S ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; FLUTICASONE; FLUTICASONE PROPIONATE PLUS SALMETEROL; PLACEBO; PROTEIN P53;

ADULT; ARTICLE; BRONCHUS BIOPSY; CELL CYCLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE ACTIVITY; EPITHELIUM CELL; EXTRACELLULAR MATRIX; FEMALE; FOCAL ADHESION; FORCED EXPIRATORY VOLUME; GAP JUNCTION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RESPIRATORY EPITHELIUM; SAINT GEORGE RESPIRATORY QUESTIONNAIRE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UPREGULATION;

COPD ÀÜ MECHANISMS;

AGED; ALBUTEROL; ANDROSTADIENES; ANTI-INFLAMMATORY AGENTS; DISEASE PROGRESSION; DRUG THERAPY, COMBINATION; FEMALE; FORCED EXPIRATORY VOLUME; GENE EXPRESSION PROFILING; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TIME FACTORS; UP-REGULATION;

EID: 84890314105     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2012-202878     Document Type: Article

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