Genetic variants of the LIN28B gene predict severe radiation pneumonitis in patients with non-small cell lung cancer treated with definitive radiation therapy

European Journal of Cancer

Volumn 50, Issue 10, 2014, Pages 1706-1716

  Wen, Juyi ^a,b   Liu, Hongliang ^c   Wang, Qiming ^b   Liu, Zhensheng ^c   Li, Yangkai ^c   Xiong, Huihua ^b   Xu, Ting ^b   Li, Peng ^b   Wang, Li E ^b   Gomez, Daniel R ^b   Mohan, Radhe ^b   Komaki, Ritsuko ^b   Liao, Zhongxing ^b   Wei, Qingyi ^c  

^a NAVY GENERAL HOSPITAL   (China)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Hazards ratio; Inflammation; LIN28; Non small cell lung cancer; Polymorphisms; Radiation pneumonitis

Indexed keywords

ANTINEOPLASTIC AGENT; MESSENGER RNA;

ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; DEFINITIVE RADIATION THERAPY; DISEASE SEVERITY; FEMALE; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; LIN28A GENE; LIN28B GENE; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION INJURY; RADIATION PNEUMONIA; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SQUAMOUS CELL CARCINOMA; VERY ELDERLY;

HAZARDS RATIO; INFLAMMATION; LIN28; NON-SMALL CELL LUNG CANCER; POLYMORPHISMS; RADIATION PNEUMONITIS;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CHEMORADIOTHERAPY; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KAPLAN-MEIER ESTIMATE; LIKELIHOOD FUNCTIONS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; RADIATION DOSAGE; RADIATION PNEUMONITIS; RISK FACTORS; RNA-BINDING PROTEINS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SMOKING; TIME FACTORS; TREATMENT OUTCOME;

EID: 84901748432     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.03.008     Document Type: Article

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