Epidermal growth factor receptor-tyrosine kinase inhibitor (gefitinib) augments pneumonitis, but attenuates lung fibrosis in response to radiation injury in rats

Journal of Medical Investigation

Volumn 59, Issue 1-2, 2012, Pages 174-185

  Miyake, Keiko ^a   Tani, Kenji ^a   Kakiuchi, Soji ^a   Suzuka, Chiyuki ^a   Toyoda, Yuko ^a   Kishi, Jun ^a   Tezuka, Toshifumi ^a   Yuasa, Shino ^a   Hanibuchi, Masaki ^a   Aono, Yoshinori ^a   Nishioka, Yasuhiko ^a   Sone, Saburo ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

Epidermal growth factor receptor; Gefitinib; Radiation pneumonitis

Indexed keywords

COLLAGEN; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; INTERLEUKIN 1BETA; INTERLEUKIN 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DOWN REGULATION; DRUG EFFECT; DRUG RESPONSE; EPIDERMAL GROWTH FACTOR RECEPTOR GENE; HISTOPATHOLOGY; INFLAMMATORY CELL; INTERSTITIAL PNEUMONIA; IRRADIATION; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG LAVAGE; MALE; NONHUMAN; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RAT; RECEPTOR GENE; RISK BENEFIT ANALYSIS; WEIGHT REDUCTION;

RATTUS; RATTUS NORVEGICUS;

EID: 84857680343     PISSN: 13431420     EISSN: None     Source Type: Journal    
DOI: 10.2152/jmi.59.174     Document Type: Article

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