Mutation of SLC35D3 Causes Metabolic Syndrome by Impairing Dopamine Signaling in Striatal D1 Neurons

PLoS Genetics

Volumn 10, Issue 2, 2014, Pages

  Zhang, Zhe ^a,b   Hao, Chan Juan ^a,b,c   Li, Chang Gui ^d   Zang, Dong Jie ^a   Zhao, Jing ^e   Li, Xiao Nan ^f   Wei, Ai Hua ^g   Wei, Zong Bo ^a,b   Yang, Lin ^a   He, Xin ^a   Zhen, Xue Chu ^h   Gao, Xiang ^e   Speakman, John R ^a,i   Li, Wei ^a  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c NATIONAL RESEARCH INSTITUTE FOR FAMILY PLANNING   (China)

^d QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^e NANJING UNIVERSITY   (China)

^f NANJING MEDICAL UNIVERSITY   (China)

^g CAPITAL MEDICAL UNIVERSITY   (China)

^h MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

ⁱ UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 1 RECEPTOR; REGULATOR PROTEIN; SLC35D3 PROTEIN; UNCLASSIFIED DRUG; DOPAMINE; DRD1A PROTEIN, MOUSE; GLUCOSE TRANSPORTER; SLC35D3 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN REGION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENDOSOME; ENERGY EXPENDITURE; FEMALE; GENE LOCATION; GENE LOCUS; GENE MUTATION; MALE; METABOLIC SYNDROME X; MOUSE; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OBESITY; PHENOTYPE; PROTEIN INTERACTION; RECESSIVE GENE; SEQUENCE TAGGED SITE; SIGNAL TRANSDUCTION; SLC35D3 GENE; STRIATE CORTEX; ANIMAL; CENTRAL NERVOUS SYSTEM; GENETICS; HUMAN; METABOLISM; MUTATION; NERVE CELL; PATHOLOGY; VISUAL CORTEX;

ANIMALS; CENTRAL NERVOUS SYSTEM; DOPAMINE; FEMALE; HUMANS; MALE; METABOLIC SYNDROME X; MICE; MONOSACCHARIDE TRANSPORT PROTEINS; MUTATION; NEURONS; OBESITY; RECEPTORS, DOPAMINE D1; SIGNAL TRANSDUCTION; VISUAL CORTEX;

EID: 84901744101     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004124     Document Type: Article

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