Structural basis for the recognition of peptide RJPXD33 by acyltransferases in lipid a biosynthesis

Journal of Biological Chemistry

Volumn 289, Issue 22, 2014, Pages 15527-15535

  Jenkins, Ronald J ^a   Heslip, Kyle A ^a   Meagher, Jennifer L ^a   Stuckey, Jeanne A ^a   Dotson, Garry D ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; ESCHERICHIA COLI;

ACYL-ACP; ACYLTRANSFERASES; ANTIBACTERIAL PEPTIDES; ANTIBACTERIALS; LIPID A; PEPTIDOMIMETICS; SMALL MOLECULES; STRUCTURAL BASIS;

PEPTIDES;

3 OXOACYL ACYL CARRIER PROTEIN REDUCTASE; ACYLTRANSFERASE; BETA HYDROXYACYL PANTETHEINE; LIPID A; PANTETHEINE; PROTEIN INHIBITOR; RJPXD 33; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE 3 O (ACYL) GLUCOSAMINE ACYLTRANSFERASE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE ACYLTRANSFERASE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; DRUG STRUCTURE; ESCHERICHIA COLI; LIPOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; STRUCTURE ANALYSIS;

ACYL CARRIER PROTEIN (ACP); ACYLTRANSFERASE; ANTIMICROBIAL PEPTIDE (AMP); ENZYME INHIBITOR; LIPID A; LIPOPOLYSACCHARIDE (LPS); LPXA; PEPTIDES; X-RAY CRYSTALLOGRAPHY;

ACYL CARRIER PROTEIN; ACYLTRANSFERASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FATTY ACID SYNTHASE, TYPE II; LIPID A; MODELS, MOLECULAR; PANTETHEINE; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84901715691     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.564278     Document Type: Article

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