Bacterial Superantigens Promote Acute Nasopharyngeal Infection by Streptococcus pyogenes in a Human MHC Class II-Dependent Manner

PLoS Pathogens

Volumn 10, Issue 5, 2014, Pages

  Kasper, Katherine J ^a   Zeppa, Joseph J ^a   Wakabayashi, Adrienne T ^a   Xu, Stacey X ^a   Mazzuca, Delfina M ^a   Welch, Ian ^b   Baroja, Miren L ^a,c   Kotb, Malak ^d   Cairns, Ewa ^a   Cleary, P Patrick ^e   Haeryfar, S M Mansour ^a,c   McCormick, John K ^a,c  

^a WESTERN UNIVERSITY   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF NORTH DAKOTA SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^e UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; SUPERANTIGEN; VIRULENCE FACTOR; BACTERIAL PROTEIN; EXOTOXIN; HLA ANTIGEN CLASS 2; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; SPEA PROTEIN, STREPTOCOCCUS PYOGENES;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; COLONY FORMING UNIT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE MUTATION; GENETIC POLYMORPHISM; HISTOLOGY; HUMAN; HUMORAL IMMUNITY; HYDROLYSIS; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; INFLAMMATION; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHINOPHARYNGITIS; STREPTOCOCCUS PYOGENES; VACCINATION; ACUTE DISEASE; ANIMAL; C57BL MOUSE; GENETICS; IMMUNOLOGY; METABOLISM; NASOPHARYNX; STREPTOCOCCAL INFECTIONS; T LYMPHOCYTE;

ACUTE DISEASE; ANIMALS; BACTERIAL PROTEINS; EXOTOXINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MEMBRANE PROTEINS; MICE, INBRED C57BL; NASOPHARYNX; RECEPTORS, ANTIGEN, T-CELL; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS PYOGENES; SUPERANTIGENS; T-LYMPHOCYTES;

EID: 84901688156     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004155     Document Type: Article

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