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Volumn 9, Issue 3, 2013, Pages 369-376

The application of aptamers in cancer research: An up-to-date review

Author keywords

aptamer; biomarker; cancer; molecular therapy

Indexed keywords

APTAMER; BIOLOGICAL MARKER; DENDRIMER; DNA; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GOLD NANOPARTICLE; LIGAND; NANOCARRIER; NANOMATERIAL; POLO LIKE KINASE 1; PROTEIN BCL 2; PROTEIN BCL XL; RNA; SMALL INTERFERING RNA; VASCULOTROPIN; VASCULOTROPIN 165;

EID: 84874885652     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.12.201     Document Type: Review
Times cited : (46)

References (87)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 144(5), 646-674 (2011
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 80053906346 scopus 로고    scopus 로고
    • Cancer prevention and early detection efforts continue to make strides
    • Printz C. Cancer prevention and early detection efforts continue to make strides. Cancer 117(20), 4574-4575 (2011
    • (2011) Cancer , vol.117 , Issue.20 , pp. 4574-4575
    • Printz, C.1
  • 3
    • 79959676586 scopus 로고    scopus 로고
    • The functional cancer map: A systems-level synopsis of genetic deregulation in cancer
    • Krupp M, Maass T, Marquardt JU et al. The functional cancer map: A systems-level synopsis of genetic deregulation in cancer. BMC Med. Genomics 4, 53 (2011
    • (2011) BMC Med. Genomics , vol.4 , Issue.53
    • Krupp, M.1    Maass, T.2    Marquardt, J.U.3
  • 4
    • 79960118993 scopus 로고    scopus 로고
    • Organ-specific markers in circulating tumor cell screening: An early indicator of metastasis-capable malignancy
    • Paterlini-Bréchot P. Organ-specific markers in circulating tumor cell screening: An early indicator of metastasis-capable malignancy. Future Oncol. 7(7), 849-871 (2011
    • (2011) Future Oncol , vol.7 , Issue.7 , pp. 849-871
    • Paterlini-Bréchot, P.1
  • 5
    • 79952845113 scopus 로고    scopus 로고
    • Predictive markers of colorectal cancer liver metastases
    • Govindarajan A, Paty PB. Predictive markers of colorectal cancer liver metastases. Future Oncol. 7(2), 299-307 (2011
    • (2011) Future Oncol , vol.7 , Issue.2 , pp. 299-307
    • Govindarajan, A.1    Paty, P.B.2
  • 8
    • 78651367790 scopus 로고    scopus 로고
    • Methods for measuring aptamer-protein equilibria: A review
    • Jing M, Bowser MT. Methods for measuring aptamer-protein equilibria: A review. Anal. Chim. Acta 686(1-2), 9-18 (2011
    • (2011) Anal. Chim. Acta , vol.686 , Issue.1-2 , pp. 9-18
    • Jing, M.1    Bowser, M.T.2
  • 9
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249(4968), 505-510 (1990
    • (1990) Science , vol.249 , Issue.4968 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 10
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands. Nature 346(6287), 818-822 (1990
    • (1990) Nature , vol.346 , Issue.6287 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 11
    • 80052213111 scopus 로고    scopus 로고
    • Aptamers against cell surface receptors: Selection, modification and application
    • Wang J, Li G. Aptamers against cell surface receptors: Selection, modification and application. Curr. Med. Chem. 18(27), 4107-4116 (2011
    • (2011) Curr. Med. Chem , vol.18 , Issue.27 , pp. 4107-4116
    • Wang, J.1    Li, G.2
  • 14
    • 79958122939 scopus 로고    scopus 로고
    • Aptamers: Potential applications to pancreatic cancer therapy
    • Rialon KL, White RR. Aptamers: Potential applications to pancreatic cancer therapy. Anticancer Agents Med. Chem. 11(5), 434-441 (2011
    • (2011) Anticancer Agents Med. Chem , vol.11 , Issue.5 , pp. 434-441
    • Rialon, K.L.1    White, R.R.2
  • 15
    • 77954678126 scopus 로고    scopus 로고
    • Aptamer applications for targeted cancer therapy
    • Barbas AS, Mi J, Clary BM, White RR. Aptamer applications for targeted cancer therapy. Future Oncol. 6(7), 1117-1126 (2010
    • (2010) Future Oncol , vol.6 , Issue.7 , pp. 1117-1126
    • Barbas, A.S.1    Mi, J.2    Clary, B.M.3    White, R.R.4
  • 16
    • 67650672206 scopus 로고    scopus 로고
    • The development and testing of aptamers for cancer
    • Barbas AS, White RR. The development and testing of aptamers for cancer. Curr. Opin. Investig. Drugs 10(6), 572-578 (2009
    • (2009) Curr. Opin. Investig. Drugs , vol.10 , Issue.6 , pp. 572-578
    • Barbas, A.S.1    White, R.R.2
  • 19
    • 78650149915 scopus 로고    scopus 로고
    • Aptamer-based multiplexed proteomic technology for biomarker discovery
    • Gold L, Ayers D, Bertino J et al. Aptamer-based multiplexed proteomic technology for biomarker discovery. PLoS One 5(12), e15004 (2010
    • (2010) PLoS One , vol.5 , Issue.12
    • Gold, L.1    Ayers, D.2    Bertino, J.3
  • 20
    • 80054085670 scopus 로고    scopus 로고
    • Fluorescence protection assay: A novel homogeneous assay platform toward development of aptamer sensors for protein detection
    • Wang HQ, Wu Z, Tang LJ, Yu RQ, Jiang JH. Fluorescence protection assay: A novel homogeneous assay platform toward development of aptamer sensors for protein detection. Nucleic Acids Res. 39(18), e122 (2011
    • (2011) Nucleic Acids Res , vol.39 , Issue.18 , pp. 122
    • Wang, H.Q.1    Wu, Z.2    Tang, L.J.3    Yu, R.Q.4    Jiang, J.H.5
  • 21
    • 0036192756 scopus 로고    scopus 로고
    • Aptasensors-The future of biosensing?
    • O'Sullivan CK. Aptasensors-The future of biosensing? Anal. Bioanal. Chem. 372(1), 44-48 (2002
    • (2002) Anal Bioanal. Chem , vol.372 , Issue.1 , pp. 44-48
    • O'Sullivan, C.K.1
  • 22
    • 1542402193 scopus 로고    scopus 로고
    • Design and synthesis of functional polymers by in vitro selection
    • Ito Y. Design and synthesis of functional polymers by in vitro selection. Polym. Adv. Technol. 15, 3-14 (2004
    • (2004) Polym. Adv. Technol , vol.15 , pp. 3-14
    • Ito, Y.1
  • 23
    • 78650121234 scopus 로고    scopus 로고
    • Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer
    • Ostroff RM, Bigbee WL, Franklin W et al. Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer. PLoS One 5(12), e15003 (2010
    • (2010) PLoS One , vol.5 , Issue.12
    • Ostroff, R.M.1    Bigbee, W.L.2    Franklin, W.3
  • 24
    • 33747053632 scopus 로고    scopus 로고
    • Aptamers evolved from live cells as effective molecular probes for cancer study
    • Shangguan D, Li Y, Tang Z et al. Aptamers evolved from live cells as effective molecular probes for cancer study. Proc. Natl Acad. Sci. USA 103(32), 11838-11843 (2006
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.32 , pp. 11838-11843
    • Shangguan, D.1    Li, Y.2    Tang, Z.3
  • 26
    • 70449938293 scopus 로고    scopus 로고
    • Highly efficient capture and enumeration of low abundance prostate cancer cells using prostate-specific membrane antigen aptamers immobilized to a polymeric microfluidic device
    • Dharmasiri U, Balamurugan S, Adams AA, Okagbare PI, Obubuafo A, Soper SA. Highly efficient capture and enumeration of low abundance prostate cancer cells using prostate-specific membrane antigen aptamers immobilized to a polymeric microfluidic device. Electrophoresis 30(18), 3289-3300 (2009
    • (2009) Electrophoresis , vol.30 , Issue.18 , pp. 3289-3300
    • Dharmasiri, U.1    Balamurugan, S.2    Adams, A.A.3    Okagbare, P.I.4    Obubuafo, A.5    Soper, S.A.6
  • 28
    • 0035844150 scopus 로고    scopus 로고
    • Systematic evolution of a DNA aptamer binding to rat brain tumor microvessles
    • Blank M, Weinschenk T, Priemer M, Schluesener H. Systematic evolution of a DNA aptamer binding to rat brain tumor microvessles. J. Biol. Chem. 276(19), 16464-16468 (2001
    • (2001) J. Biol. Chem , vol.276 , Issue.19 , pp. 16464-16468
    • Blank, M.1    Weinschenk, T.2    Priemer, M.3    Schluesener, H.4
  • 29
    • 0347364648 scopus 로고    scopus 로고
    • A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment
    • Daniels DA, Chen H, Hicke BJ, Swiderek KM, Gold L. A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment. Proc. Natl Acad. Sci. USA 100(26), 15416-15421 (2003
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.26 , pp. 15416-15421
    • Daniels, D.A.1    Chen, H.2    Hicke, B.J.3    Swiderek, K.M.4    Gold, L.5
  • 30
    • 0037430933 scopus 로고    scopus 로고
    • Single-stranded DNA aptamers that bind differentiated but not parental cells: Subtractive systematic evolution of ligands by exponential enrichment
    • Wang C, Zhang M, Yang G et al. Single-stranded DNA aptamers that bind differentiated but not parental cells: Subtractive systematic evolution of ligands by exponential enrichment. J. Biotechnol. 102(1), 15-22 (2003
    • (2003) J. Biotechnol , vol.102 , Issue.1 , pp. 15-22
    • Wang, C.1    Zhang, M.2    Yang, G.3
  • 31
    • 34447316180 scopus 로고    scopus 로고
    • Selection of aptamers for molecular recognition and characterization of cancer cells
    • Tang Z, Shangguan D, Wang K et al. Selection of aptamers for molecular recognition and characterization of cancer cells. Anal. Chem. 79(13), 4900-4907 (2007
    • (2007) Anal. Chem , vol.79 , Issue.13 , pp. 4900-4907
    • Tang, Z.1    Shangguan, D.2    Wang, K.3
  • 32
    • 60149090182 scopus 로고    scopus 로고
    • Molecular recognition of acute myeloid leukemia using aptamers
    • Sefah K, Tang Z, Shangguan D et al. Molecular recognition of acute myeloid leukemia using aptamers. Leukemia 23(2), 235-244 (2009
    • (2009) Leukemia , vol.23 , Issue.2 , pp. 235-244
    • Sefah, K.1    Tang, Z.2    Shangguan, D.3
  • 33
    • 38849155858 scopus 로고    scopus 로고
    • Identification of liver cancer-specific aptamers using whole live cells
    • Shangguan D, Meng L, Cao ZC et al. Identification of liver cancer-specific aptamers using whole live cells. Anal. Chem. 80(3), 721-728 (2008
    • (2008) Anal. Chem , vol.80 , Issue.3 , pp. 721-728
    • Shangguan, D.1    Meng, L.2    Cao, Z.C.3
  • 34
    • 46049096465 scopus 로고    scopus 로고
    • Molecular recognition of small-cell lung cancer cells using aptamers
    • Chen HW, Medley CD, Sefah K et al. Molecular recognition of small-cell lung cancer cells using aptamers. Chem. Med. Chem. 3(6), 991-1001 (2008
    • (2008) Chem. Med. Chem , vol.3 , Issue.6 , pp. 991-1001
    • Chen, H.W.1    Medley, C.D.2    Sefah, K.3
  • 35
    • 34249870129 scopus 로고    scopus 로고
    • Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples
    • Shangguan D, Cao ZC, Li Y, Tan W. Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples. Clin. Chem. 53(6), 1153-1158 (2007
    • (2007) Clin. Chem , vol.53 , Issue.6 , pp. 1153-1158
    • Shangguan, D.1    Cao, Z.C.2    Li, Y.3    Tan, W.4
  • 37
    • 78650582001 scopus 로고    scopus 로고
    • Current status of molecular markers for early detection of sporadic pancreatic cancer
    • Chakraborty S, Baine MJ, Sasson AR, Batra SK. Current status of molecular markers for early detection of sporadic pancreatic cancer. Biochim. Biophys. Acta 1815(1), 44-64 (2011
    • (2011) Biochim. Biophys. Acta , vol.1815 , Issue.1 , pp. 44-64
    • Chakraborty, S.1    Baine, M.J.2    Sasson, A.R.3    Batra, S.K.4
  • 38
    • 79953706298 scopus 로고    scopus 로고
    • A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia
    • Mallikaratchy PR, Ruggiero A, Gardner JR et al. A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia. Nucleic Acids Res. 39(6), 2458-2469 (2011
    • (2011) Nucleic Acids Res , vol.39 , Issue.6 , pp. 2458-2469
    • Mallikaratchy, P.R.1    Ruggiero, A.2    Gardner, J.R.3
  • 39
    • 77958449045 scopus 로고    scopus 로고
    • Stable feature selection for biomarker discovery
    • He Z, Yu W. Stable feature selection for biomarker discovery. Comput. Biol. Chem. 34(4), 215-225 (2010
    • (2010) Comput. Biol. Chem , vol.34 , Issue.4 , pp. 215-225
    • He, Z.1    Yu, W.2
  • 40
    • 76749126504 scopus 로고    scopus 로고
    • Identification of a novel potential biomarker in a model of hemorrhagic shock and valproic acid treatment
    • Li Y, Liu B, Dillon ST et al. Identification of a novel potential biomarker in a model of hemorrhagic shock and valproic acid treatment. J. Surg. Res. 159(1), 474-481 (2010
    • (2010) J. Surg. Res , vol.159 , Issue.1 , pp. 474-481
    • Li, Y.1    Liu, B.2    Dillon, S.T.3
  • 41
    • 56349096465 scopus 로고    scopus 로고
    • Integrative genomic data mining for discovery of potential blood-borne biomarkers for early diagnosis of cancer
    • Yang Y, Iyer LK, Adelstein SJ, Kassis AI. Integrative genomic data mining for discovery of potential blood-borne biomarkers for early diagnosis of cancer. PLoS One 3(11), e3661 (2008
    • (2008) PLoS One , vol.3 , Issue.11
    • Yang, Y.1    Iyer, L.K.2    Adelstein, S.J.3    Kassis, A.I.4
  • 42
    • 70350567762 scopus 로고    scopus 로고
    • Comparative analysis of the liver and plasma proteomes as a novel and powerful strategy for hepatocellular carcinoma biomarker discovery
    • Beretta L. Comparative analysis of the liver and plasma proteomes as a novel and powerful strategy for hepatocellular carcinoma biomarker discovery. Cancer Lett. 286(1), 134-139 (2009
    • (2009) Cancer Lett , vol.286 , Issue.1 , pp. 134-139
    • Beretta, L.1
  • 43
    • 84860579546 scopus 로고    scopus 로고
    • Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker
    • Ray P, Rialon-Guenara KL, Veras E, Sullenger BA, White RR. Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer biomarker. Clin. Invest. 122(5), 1734-1741 (2012
    • (2012) Clin. Invest , vol.122 , Issue.5 , pp. 1734-1741
    • Ray, P.1    Rialon-Guenara, K.L.2    Veras, E.3    Sullenger, B.A.4    White, R.R.5
  • 44
    • 46049086644 scopus 로고    scopus 로고
    • Cell-specific aptamer probes for membrane protein elucidation in cancer cells
    • Shangguan D, Cao Z, Meng L et al. Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J. Proteome Res. 7(5), 2133-2139 (2008
    • (2008) J. Proteome Res , vol.7 , Issue.5 , pp. 2133-2139
    • Shangguan, D.1    Cao, Z.2    Meng, L.3
  • 45
    • 38349061033 scopus 로고    scopus 로고
    • Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in burkitt's lymphoma cell
    • Mallikaratchy P, Tang Z, Kwame S, Meng L, Shangguan D, Tan W. Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in burkitt's lymphoma cell. Mol. Cell. Proteomics 6(12), 2230-2238 (2007
    • (2007) Mol. Cell. Proteomics , vol.6 , Issue.12 , pp. 2230-2238
    • Mallikaratchy, P.1    Tang, Z.2    Kwame, S.3    Meng, L.4    Shangguan, D.5    Tan, W.6
  • 46
    • 84861598373 scopus 로고    scopus 로고
    • In vivo uses of aptamers selected against cell surface biomarkers for therapy and molecular imaging
    • Cibiel A, Pestourie C, Ducongé F. In vivo uses of aptamers selected against cell surface biomarkers for therapy and molecular imaging. Biochimie 94(7), 1595-1606 (2012
    • (2012) Biochimie , vol.94 , Issue.7 , pp. 1595-1606
    • Cibiel, A.1    Pestourie, C.2    Ducongé, F.3
  • 47
    • 80052230213 scopus 로고    scopus 로고
    • Improving the stability of aptamers by chemical modification
    • Wang RE, Wu H, Niu Y, Cai J. Improving the stability of aptamers by chemical modification. Curr. Med. Chem. 18(27), 4126-4138 (2011
    • (2011) Curr. Med. Chem , vol.18 , Issue.27 , pp. 4126-4138
    • Wang, R.E.1    Wu, H.2    Niu, Y.3    Cai, J.4
  • 48
    • 7444223607 scopus 로고    scopus 로고
    • Nanoparticle-Aptamer bioconjugates: A new approach for targeting prostate cancer cells
    • Farokhzad OC, Jon S, Khademhosseini A, Tran TN, Lavan DA, Langer R. Nanoparticle-Aptamer bioconjugates: A new approach for targeting prostate cancer cells. Cancer Res. 64(21), 7668-7672 (2004
    • (2004) Cancer Res , vol.64 , Issue.21 , pp. 7668-7672
    • Farokhzad, O.C.1    Jon, S.2    Khademhosseini, A.3    Tran, T.N.4    Lavan, D.A.5    Langer, R.6
  • 49
    • 81155150134 scopus 로고    scopus 로고
    • Molecular aptamers for drug delivery
    • Tan W, Wang H, Chen Y et al. Molecular aptamers for drug delivery. Trends Biotechnol. 29(12), 634-640 (2011
    • (2011) Trends Biotechnol , vol.29 , Issue.12 , pp. 634-640
    • Tan, W.1    Wang, H.2    Chen, Y.3
  • 50
    • 72449177819 scopus 로고    scopus 로고
    • Aptamer-nanoparticle strip biosensor for rapid and sensitive detection of cancer cells
    • Mao X, Phillips JA, Xu H, Tan W, Zeng L, Liu G. Aptamer-nanoparticle strip biosensor for rapid and sensitive detection of cancer cells. Anal. Chem. 81(24), 10013-10018 (2009
    • (2009) Anal. Chem , vol.81 , Issue.24 , pp. 10013-10018
    • Mao, X.1    Phillips, J.A.2    Xu, H.3    Tan, W.4    Zeng, L.5    Liu, G.6
  • 51
    • 32544461022 scopus 로고    scopus 로고
    • Chemical biology: Aptamers in nanoland
    • Famulok M, Mayer G. Chemical biology: Aptamers in nanoland. Nature 439(7077), 666-669 (2006
    • (2006) Nature , vol.439 , Issue.7077 , pp. 666-669
    • Famulok, M.1    Mayer, G.2
  • 52
    • 33646580369 scopus 로고    scopus 로고
    • Aptamer-conjugated nanoparticles for selective collection and detection of cancer cells
    • Herr JK, Smith JE, Medley CD, Shangguan D, Tan W. Aptamer-conjugated nanoparticles for selective collection and detection of cancer cells. Anal. Chem. 78(9), 2918-2924 (2006
    • (2006) Anal. Chem , vol.78 , Issue.9 , pp. 2918-2924
    • Herr, J.K.1    Smith, J.E.2    Medley, C.D.3    Shangguan, D.4    Tan, W.5
  • 53
    • 77953448762 scopus 로고    scopus 로고
    • Nanoparticle-Aptamer conjugates for cancer cell targeting and detection
    • Estévez MC, Huang YF, Kang H et al. Nanoparticle-Aptamer conjugates for cancer cell targeting and detection. Methods Mol. Biol. 624, 235-248 (2010
    • (2010) Methods Mol. Biol , vol.624 , pp. 235-248
    • Estévez, M.C.1    Huang, Y.F.2    Kang, H.3
  • 54
    • 61449210870 scopus 로고    scopus 로고
    • Enrichment of cancer cells using aptamers immobilized on a microfluidic channel
    • Phillips JA, Xu Y, Xia Z, Fan ZH, Tan W. Enrichment of cancer cells using aptamers immobilized on a microfluidic channel. Anal. Chem. 81(3), 1033-1039 (2009
    • (2009) Anal. Chem , vol.81 , Issue.3 , pp. 1033-1039
    • Phillips, J.A.1    Xu, Y.2    Xia, Z.3    Fan, Z.H.4    Tan, W.5
  • 55
    • 69749097619 scopus 로고    scopus 로고
    • Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells
    • Xu Y, Phillips JA, Yan J, Li Q, Fan ZH, Tan W. Aptamer-based microfluidic device for enrichment, sorting, and detection of multiple cancer cells. Anal. Chem. 81(7), 7436-7442 (2009
    • (2009) Anal. Chem , vol.81 , Issue.7 , pp. 7436-7442
    • Xu, Y.1    Phillips, J.A.2    Yan, J.3    Li, Q.4    Fan, Z.H.5    Tan, W.6
  • 57
    • 80052229081 scopus 로고    scopus 로고
    • Tumor-Targeted drug delivery with aptamers
    • Zhang Y, Hong H, Cai W. Tumor-Targeted drug delivery with aptamers. Curr. Med. Chem. 18(27), 4185-4194 (2011
    • (2011) Curr. Med. Chem , vol.18 , Issue.27 , pp. 4185-4194
    • Zhang, Y.1    Hong, H.2    Cai, W.3
  • 58
    • 0035151050 scopus 로고    scopus 로고
    • Highly specific antiangiogenic therapy is effective in suppressing growth of experimental Wilms tumors
    • Huang J, Moore J, Soffer S et al. Highly specific antiangiogenic therapy is effective in suppressing growth of experimental Wilms tumors. J. Pediatr. Surg. 36(2), 357-361 (2001
    • (2001) J. Pediatr. Surg , vol.36 , Issue.2 , pp. 357-361
    • Huang, J.1    Moore, J.2    Soffer, S.3
  • 59
    • 0034466813 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys
    • Drolet DW, Nelson J, Tucker CE et al. Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys. Pharmaceut. Res. 17(12) 1503-1510 (2000
    • (2000) Pharmaceut. Res , vol.17 , Issue.12 , pp. 1503-1510
    • Drolet, D.W.1    Nelson, J.2    Tucker, C.E.3
  • 60
    • 33847767005 scopus 로고    scopus 로고
    • Potentiality of small interfering RNAs (siRNA) as recent therapeutic targets for gene-silencing
    • Chakraborty C. Potentiality of small interfering RNAs (siRNA) as recent therapeutic targets for gene-silencing. Curr. Drug Targets 8(3), 469-482 (2007
    • (2007) Curr. Drug Targets , vol.8 , Issue.3 , pp. 469-482
    • Chakraborty, C.1
  • 62
    • 77952380547 scopus 로고    scopus 로고
    • Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay
    • Pastor F, Kolonias D, Giangrande PH, Gilboa E. Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay. Nature 465(7295), 227-230 (2010
    • (2010) Nature , vol.465 , Issue.7295 , pp. 227-230
    • Pastor, F.1    Kolonias, D.2    Giangrande, P.H.3    Gilboa, E.4
  • 63
    • 84864447484 scopus 로고    scopus 로고
    • Delivery of chemo-sensitizing siRNAs to HER2+- breast cancer cells using RNA aptamers
    • Thiel KW, Hernandez LI, Dassie JP et al. Delivery of chemo-sensitizing siRNAs to HER2+- breast cancer cells using RNA aptamers. Nucleic Acids Res. 40(13), 6319-6337 (2012
    • (2012) Nucleic Acids Res , vol.40 , Issue.13 , pp. 6319-6337
    • Thiel, K.W.1    Hernandez, L.I.2    Dassie, J.P.3
  • 64
    • 70249110439 scopus 로고    scopus 로고
    • Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors
    • Dassie JP, Liu XY, Thomas GS et al. Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors. Nat. Biotechnol. 27(9), 839-849 (2009
    • (2009) Nat. Biotechnol , vol.27 , Issue.9 , pp. 839-849
    • Dassie, J.P.1    Liu, X.Y.2    Thomas, G.S.3
  • 65
    • 55449127119 scopus 로고    scopus 로고
    • Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2
    • Wullner U, Neef I, Eller A, Kleines M, Tur MK, Barth S. Cell-specific induction of apoptosis by rationally designed bivalent aptamer-siRNA transcripts silencing eukaryotic elongation factor 2. Curr. Cancer Drug Targets 8(7), 554-565 (2008
    • (2008) Curr. Cancer Drug Targets , vol.8 , Issue.7 , pp. 554-565
    • Wullner, U.1    Neef, I.2    Eller, A.3    Kleines, M.4    Tur, M.K.5    Barth, S.6
  • 66
    • 77953359872 scopus 로고    scopus 로고
    • A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro
    • Kawala E, Ashihara E, Nakaoawa Y et al. A combination of a DNA-chimera siRNA against PLK-1 and zoledronic acid suppresses the growth of malignant mesothelioma cells in vitro. Cancer Lett. 294(2), 245-253 (2010
    • (2010) Cancer Lett , vol.294 , Issue.2 , pp. 245-253
    • Kawala, E.1    Ashihara, E.2    Nakaoawa, Y.3
  • 67
    • 79952440644 scopus 로고    scopus 로고
    • Antiangiogenic therapy using nanotechnological-based delivery system
    • Kanwar JR, Mahidhara G, Kanwar RK. Antiangiogenic therapy using nanotechnological-based delivery system. Drug Discov. Today 16 (5-6), 188-202 (2011
    • (2011) Drug Discov. Today , vol.16 , Issue.5-6 , pp. 188-202
    • Kanwar, J.R.1    Mahidhara, G.2    Kanwar, R.K.3
  • 68
    • 81855218276 scopus 로고    scopus 로고
    • Chimeric aptamers in cancer cell-Targeted drug delivery
    • Kanwar JR, Roy K, Kanwar RK. Chimeric aptamers in cancer cell-Targeted drug delivery. Crit. Rev. Biochem. Mol. Biol. 46(6), 459-477 (2011
    • (2011) Crit. Rev. Biochem. Mol. Biol , vol.46 , Issue.6 , pp. 459-477
    • Kanwar, J.R.1    Roy, K.2    Kanwar, R.K.3
  • 69
    • 77950051368 scopus 로고    scopus 로고
    • Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex
    • Kim E, Jung Y, Choi H et al. Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex. Biomaterials 31(16), 4592-4599 (2010
    • (2010) Biomaterials , vol.31 , Issue.16 , pp. 4592-4599
    • Kim, E.1    Jung, Y.2    Choi, H.3
  • 70
    • 80054681184 scopus 로고    scopus 로고
    • Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates
    • Lee IH, An S, Yu MK, Kwon HK, Im SH, Jon S. Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates. J. Control. Release 155(3), 435-441 (2011
    • (2011) J. Control. Release , vol.155 , Issue.3 , pp. 435-441
    • Lee, I.H.1    An, S.2    Yu, M.K.3    Kwon, H.K.4    Im, S.H.5    Jon, S.6
  • 71
    • 80052257765 scopus 로고    scopus 로고
    • Molecular imaging with nucleic acid aptamers
    • Hong H, Goel S, Zhang Y, Cai W. Molecular imaging with nucleic acid aptamers. Curr. Med. Chem. 18(27), 4195-4205 (2011
    • (2011) Curr. Med. Chem , vol.18 , Issue.27 , pp. 4195-4205
    • Hong, H.1    Goel, S.2    Zhang, Y.3    Cai, W.4
  • 72
    • 79959516872 scopus 로고    scopus 로고
    • Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging
    • Rockey WM, Huang L, Kloepping KC, Baumhover NJ, Giangrande PH. Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging. Bioorg. Med. Chem. 19(13), 4080-4090 (2011
    • (2011) Bioorg. Med. Chem , vol.19 , Issue.13 , pp. 4080-4090
    • Rockey, W.M.1    Huang, L.2    Kloepping, K.C.3    Baumhover, N.J.4    Giangrande, P.H.5
  • 73
    • 84865298982 scopus 로고    scopus 로고
    • DNA aptamer functionalized nanomaterials for intracellular analysis, cancer cell imaging and drug delivery
    • Xing H, Wong NY, Xiang Y, Lu Y. DNA aptamer functionalized nanomaterials for intracellular analysis, cancer cell imaging and drug delivery. Curr. Opin. Chem. Biol. 16(3-4), 429-435 (2012
    • (2012) Curr. Opin. Chem. Biol , vol.16 , Issue.3-4 , pp. 429-435
    • Xing, H.1    Wong, N.Y.2    Xiang, Y.3    Lu, Y.4
  • 74
    • 77955542791 scopus 로고    scopus 로고
    • A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer
    • Kim D, Jeong YY, Jon S. A drug-loaded aptamer-gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer. ACS Nano 4(7), 3689-3696 (2010
    • (2010) ACS Nano , vol.4 , Issue.7 , pp. 3689-3696
    • Kim, D.1    Jeong, Y.Y.2    Jon, S.3
  • 75
    • 0037099536 scopus 로고    scopus 로고
    • Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen
    • Lupold SE, Hicke BJ, Lin Y, Coffey DS. Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res. 62(14), 4029-4033 (2002
    • (2002) Cancer Res , vol.62 , Issue.14 , pp. 4029-4033
    • Lupold, S.E.1    Hicke, B.J.2    Lin, Y.3    Coffey, D.S.4
  • 76
    • 33644676039 scopus 로고    scopus 로고
    • Detection of oncoprotein platelet-derived growth factor using a fluorescent signaling complex of an aptamer and TOTO
    • Zhou C, Jiang Y, Hou S, Ma B, Fang X, Li M. Detection of oncoprotein platelet-derived growth factor using a fluorescent signaling complex of an aptamer and TOTO. Anal. Bioanal. Chem. 384(5), 1175-1180 (2006
    • (2006) Anal. Bioanal. Chem , vol.384 , Issue.5 , pp. 1175-1180
    • Zhou, C.1    Jiang, Y.2    Hou, S.3    Ma, B.4    Fang, X.5    Li, M.6
  • 77
    • 0029379767 scopus 로고
    • Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor
    • Green LS, Jellinek D, Bell C et al. Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor. Chem. Biol. 2(10), 683-695 (1995
    • (1995) Chem. Biol , vol.2 , Issue.10 , pp. 683-695
    • Green, L.S.1    Jellinek, D.2    Bell, C.3
  • 78
    • 42949170093 scopus 로고    scopus 로고
    • Selection and characterization of DNA aptamers against VEGF165 with aptamer blotting method and its application
    • Ikebukuro K, Haseagwa H, Sode K. Selection and characterization of DNA aptamers against VEGF165 with aptamer blotting method and its application. Nucleic Acids Symp. Ser. (Oxf.) (51), 399-400 (2007
    • (2007) Nucleic Acids Symp. Ser. (Oxf , vol.51 , pp. 399-400
    • Ikebukuro, K.1    Haseagwa, H.2    Sode, K.3
  • 79
    • 33846992303 scopus 로고    scopus 로고
    • Detection of protein biomarkers using RNA aptamer microarrays and enzymatically amplified SPR imaging
    • Li Y, Lee HJ, Corn RM. Detection of protein biomarkers using RNA aptamer microarrays and enzymatically amplified SPR imaging. Anal. Chem. 79(3), 1082-1088 (2007
    • (2007) Anal. Chem , vol.79 , Issue.3 , pp. 1082-1088
    • Li, Y.1    Lee, H.J.2    Corn, R.M.3
  • 80
    • 38849205404 scopus 로고    scopus 로고
    • DNA aptamers against the MUC1 tumour marker: Design of aptamer-Antibody sandwich ELISA for the early diagnosis of epithelial tumours
    • Ferreira CS, Papamichael K, Guilbault G, Schwarzacher T, Gariepy J, Missailidis S. DNA aptamers against the MUC1 tumour marker: Design of aptamer-Antibody sandwich ELISA for the early diagnosis of epithelial tumours. Anal. Bioanal. Chem. 390(4), 1039-1050 (2008
    • (2008) Anal. Bioanal. Chem , vol.390 , Issue.4 , pp. 1039-1050
    • Ferreira, C.S.1    Papamichael, K.2    Guilbault, G.3    Schwarzacher, T.4    Gariepy, J.5    Missailidis, S.6
  • 81
    • 0035966106 scopus 로고    scopus 로고
    • Tenascin-C Aptamers are generated using tumor cells and purified protein
    • Hicke BJ, Marion C, Chang Y et al. Tenascin-C Aptamers are generated using tumor cells and purified protein. J. Biol. Chem. 276(52), 48644-48654 (2001
    • (2001) J. Biol. Chem , vol.276 , Issue.52 , pp. 48644-48654
    • Hicke, B.J.1    Marion, C.2    Chang, Y.3
  • 82
    • 0034714150 scopus 로고    scopus 로고
    • Diagnostic potential of PhotoSELEX-evolved ssDNA aptamers
    • Golden MC, Collins BD, Willis MC, Koch TH. Diagnostic potential of PhotoSELEX-evolved ssDNA aptamers. J. Biotechnol. 81(2-3), 167-178 (2000
    • (2000) J. Biotechnol , vol.81 , Issue.2-3 , pp. 167-178
    • Golden, M.C.1    Collins, B.D.2    Willis, M.C.3    Koch, T.H.4
  • 83
    • 18344375927 scopus 로고    scopus 로고
    • Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase
    • Cerchia L, Ducongé F, Pestourie C et al. Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase. PLoS Biol. 3(4), e123 (2005
    • (2005) PLoS Biol , vol.3 , Issue.4
    • Cerchia, L.1    Ducongé, F.2    Pestourie, C.3
  • 84
    • 84866849562 scopus 로고    scopus 로고
    • RNA aptamer-based functional ligands of the neurotrophin receptor
    • Huang YZ, Hernandez FJ, Gu B et al. RNA aptamer-based functional ligands of the neurotrophin receptor, TrkB. Mol. Pharmacol. 82(4), 623-635 (2012
    • (2012) TrkB. Mol. Pharmacol , vol.82 , Issue.4 , pp. 623-635
    • Huang, Y.Z.1    Hernandez, F.J.2    Gu, B.3
  • 85
    • 84870615894 scopus 로고    scopus 로고
    • Targeting Axl with an high-Affinity inhibitory aptamer
    • Cerchia L, Esposito CL, Camorani S et al. Targeting Axl with an high-Affinity inhibitory aptamer. Mol. Ther. 20(12), 2291-2303 (2012
    • (2012) Mol. Ther , vol.20 , Issue.12 , pp. 2291-2303
    • Cerchia, L.1    Esposito, C.L.2    Camorani, S.3
  • 86
    • 79958158761 scopus 로고    scopus 로고
    • Inhibition of cell proliferation by an anti-EGFR aptamer
    • Li N, Nguyen HH, Byrom M, Ellington AD. Inhibition of cell proliferation by an anti-EGFR aptamer. PLoS One 6(6), e20299 (2011
    • (2011) PLoS One , vol.6 , Issue.6
    • Li, N.1    Nguyen, H.H.2    Byrom, M.3    Ellington, A.D.4
  • 87
    • 80052169101 scopus 로고    scopus 로고
    • In vitro selection of RNA aptamer and specific targeting of ErbB2 in breast cancer cells
    • Kim MY, Jeong S. In vitro selection of RNA aptamer and specific targeting of ErbB2 in breast cancer cells. Nucleic Acid Ther. 21(3), 173-178 (2011
    • (2011) Nucleic Acid Ther , vol.21 , Issue.3 , pp. 173-178
    • Kim, M.Y.1    Jeong, S.2


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