An ultra pH-sensitive and aptamer-equipped nanoscale drug-delivery system for selective killing of tumor cells

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Volumn 9, Issue 20, 2013, Pages 3477-3484

  Zhao, Nianxi ^a   You, Jian ^b   Zeng, Zihua ^a   Li, Chun ^b   Zu, Youli ^a  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

aptamers; drug delivery; hollow gold nanospheres; pH sensitive; targeted therapies

Indexed keywords

APTAMER TECHNOLOGY; APTAMERS; BIOLOGICAL CONDITIONS; CANCER THERAPEUTICS; DRUG-DELIVERY SYSTEMS; GOLD NANOSPHERES; PH SENSITIVE; TARGETED THERAPIES;

CELLS; CHEMOTHERAPY; DISEASES; DRUG DELIVERY; GOLD; NANOSPHERES; NANOTECHNOLOGY; ONCOLOGY; PH EFFECTS; TUMORS;

CYTOLOGY;

APTAMER; DOXORUBICIN; GOLD; NANOSPHERE; TUMOR MARKER;

APTAMERS; ARTICLE; CELL DEATH; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG EFFECT; HOLLOW GOLD NANOSPHERES; HUMAN; INTRACELLULAR SPACE; METABOLISM; NEOPLASM; PATHOLOGY; PH; PH SENSITIVE; TARGETED THERAPIES; TUMOR CELL LINE;

APTAMERS; DRUG DELIVERY; HOLLOW GOLD NANOSPHERES; PH SENSITIVE; TARGETED THERAPIES;

APTAMERS, NUCLEOTIDE; CELL DEATH; CELL LINE, TUMOR; DOXORUBICIN; DRUG DELIVERY SYSTEMS; GOLD; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR SPACE; NANOSPHERES; NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 84886092247     PISSN: 16136810     EISSN: 16136829     Source Type: Journal    
DOI: 10.1002/smll.201202694     Document Type: Article

References (24)

1. G. Deepa, N. A. Kumar, J. J. Pillai, G. S. Kumar, Curr. Med. Chem. 2012, 19, 6207.
2. T. Panda, K. Deepa, J. Nanosci. Nanotechnol. 2011, 11, 10279.
3. T. Lehto, K. Ezzat, U. Langel, Prog. Mol. Biol. Transl. Sci. 2011, 104, 397.
4. M. A. Iqbal, S. Md, J. K. Sahni, S. Baboota, S. Dang, J. Ali, J. Drug Target. 2012, 20, 813.
5. J. Zhu, L. Liao, X. Bian, J. Kong, P. Yang, B. Liu, Small 2012, 8, 2715.
6. L. Brannon-Peppas, J. O. Blanchette, Adv. Drug Deliv. Rev. 2012, 56, 1649.
7. I. Brigger, C. Dubernet, P. Couvreur, Adv. Drug Deliv. Rev. 2012, 54, 631.
8. S. Sultana, M. R. Khan, M. Kumar, S. Kumar, M. Ali, J. Drug Target. 2013, 21, 107.
9. Wahajuddin, S. Arora, Int. J. Nanomed. 2012, 7, 3445.
10. M. Tiwari, J. Cancer Res. Ther. 2012, 8, 19.
11. S. Bamrungsap, Z. Zhao, T. Chen, L. Wang, C. Li, T. Fu, W. Tan, Nanomedicine 2012, 7, 1253.
12. J. Panyam, V. Labhasetwar, Adv. Drug Deliv. Rev. 2003, 55, 329.
13. J. You, G. Zhang, C. Li, ACS Nano 2010, 4, 1033.
14. B. Smith, I. Lyakhov, K. Loomis, D. Needle, U. Baxa, A. Yavlovich, J. Capala, R. Blumenthal, A. Puri, J. Control. Release 2011, 153, 187.
15. A. J. Gormley, A. Malugin, A. Ray, R. Robinson, H. Ghandehari, J. Drug Target. 2011, 19, 915.
16. S. Choi, J. Lee, P. Kumar, K. Y. Lee, S. K. Lee, J. Control. Release 2011, 152, e9.
17. M. C. Estevez, Y. F. Huang, H. Kang, M. B. O'Donoghue, S. Bamrungsap, J. Yan, X. Chen, W. Tan, Methods Molec. Biol. 2010, 624, 235.
18. A. R. Oliphant, C. J. Brandl, K. Struhl, Molec. Cell. Biol. 1989, 9, 2944.
19. A. D. Ellington, J. W. Szostak, Nature 1990, 346, 818.
20. C. Tuerk, L. Gold, Science 1990, 249, 505.
21. P. Zhang, N. Zhao, Z. Zeng, C. C. Chang, Y. Zu, Am. J. Clin. Pathol. 2010, 134, 586.
22. P. Zhang, N. Zhao, Z. Zeng, Y. Feng, C. H. Tung, C. C. Chang, Y. Zu, Lab. Investigation 2009, 89, 1423.
23. Z. Zeng, P. Zhang, N. Zhao, A. M. Sheehan, C. H. Tung, C. C. Chang, Y. Zu, Mod Pathol. 2010, 23, 1553.
24. N. Zhao, H. G. Bagaria, M. S. Wong, Y. Zu, J. Nanobiotechnol. 2011, 31, 2.