Anxiolytic and antidepressant-like activities of the novel and potent non-imidazole histamine H3 receptor antagonist ST-1283

Drug Design, Development and Therapy

Volumn 8, Issue , 2014, Pages 627-637

  Bahi, Amine ^a   Schwed, Johannes Stephan ^b,c   Walter, Miriam ^b   Stark, Holger ^c   Sadek, Bassem ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^b GOETHE UNIVERSITY   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Anxiety; Depression; Histamine; R methylhistamine; ST 1283

Indexed keywords

3 (5 METHYL 4 (4 (3 (PIPERIDIN 1 YL)PROPOXY)PHENYL) 4H 1,2,4 TRIAZOL 3 YL)PYRIDINE; DIAZEPAM; FLUOXETINE; HISTAMINE H3 RECEPTOR ANTAGONIST; ST 1283; UNCLASSIFIED DRUG; 3-(5-METHYL-4-(4-(3-(PIPERIDIN-1-YL)PROPOXY)PHENYL)-4H-1,2,4-TRIAZOL-3-YL)PYRIDINE; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; HISTAMINE H3 RECEPTOR; PYRIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTIDEPRESSANT ACTIVITY; ANXIETY DISORDER; ARTICLE; CONCENTRATION RESPONSE; DEPRESSION; DRUG EFFECT; ELEVATED PLUS MAZE TEST; FORCED SWIM TEST; IN VITRO STUDY; LATENT PERIOD; MALE; MARBLE BURYING TEST; MOTOR ACTIVITY; MOUSE; NONHUMAN; NOVELTY SUPPRESSED FEEDING TEST; OPEN FIELD TEST; TAIL SUSPENSION TEST; TRANQUILIZING ACTIVITY; ANIMAL; C57BL MOUSE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; ANTI-ANXIETY AGENTS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; DEPRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE H3 ANTAGONISTS; HUMANS; MALE; MICE; MICE, INBRED C57BL; PYRIDINES; RECEPTORS, HISTAMINE H3; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84901676214     PISSN: 11778881     EISSN: None     Source Type: Journal    
DOI: 10.2147/DDDT.S63088     Document Type: Article

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