The tail suspension test

Journal of Visualized Experiments

Volumn , Issue 59, 2012, Pages 1-5

  Can, Adem ^a   Dao, David T ^a,b   Terrillion, Chantelle E ^c   Piantadosi, Sean C ^a   Bhat, Shambhu ^a   Gould, Todd D ^a,c  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

Animal models; Antidepressant; Behavioral analysis; Depression; Issue 59; Mood disorder; Mood stabilizer; Neurobiology; Neuroscience

Indexed keywords

EID: 84856934652     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Mayorga, A.J. & Lucki, I. Limitations on the use of the C57BL/6 mouse in the tail suspension test. Psychopharmacology (Berl). 155, 110-112 (2001).
2. Dao, D.T., et al. Mood Disorder Susceptibility Gene CACNA1C Modifies Mood-Related Behaviors in Mice and Interacts with Sex to Influence Behavior in Mice and Diagnosis in Humans. Biological Psychiatry. 68, 801-810 (2010).
3. Can, A.L., et al. Antidepressant-like responses to lithium in genetically diverse mouse strains. Genes, Brain and Behavior. 10, 434-443 (2011).
4. Bai, F., Li, X., Clay, M., Lindstrom, T., & Skolnick, P. Intra- and interstrain differences in models of behavioral despair. Pharmacol. Biochem. Behav. 70, 187-192 (2001).
5. Cervo, L., et al. Genotype-dependent activity of tryptophan hydroxylase-2 determines the response to citalopram in a mouse model of depression. J. Neurosci. 25, 8165-8172 (2005).
6. David, D.J., Renard, C.E., Jolliet, P., Hascoet, M., & Bourin, M. Antidepressant-like effects in various mice strains in the forced swimming test. Psychopharmacology (Berl). 166, 373-382 (2003).
7. Dulawa, S.C., Holick, K.A., Gundersen, B., & Hen, R. Effects of chronic fluoxetine in animal models of anxiety and depression. Neuropsychopharmacology. 29, 1321-1330 (2004).
8. Lucki, I., Dalvi, A., & Mayorga, A.J. Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice. Psychopharmacology (Berl). 155, 315-322 (2001).
9. Steru, L., Chermat, R., Thierry, B., & Simon, P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology (Berl). 85, 367-370 (1985).
10. Can, A., Dao, D. T., Arad, M., Terrillion, C. E., Piantadosi, S.C., & Gould, T.D. The Mouse Forced Swim Test. J. Vis. Exp. (58), e3638, DOI: 10.3791/3638 (2012).
11. Porsolt, R.D., Bertin, A., & Jalfre, M. Behavioral despair in mice: a primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 229, 327-336 (1977).
12. Porsolt, R.D., Anton, G., Blavet, N., & Jalfre, M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur. J. Pharmacol. 47, 379-391 (1978).
13. Crowley, J.J., Blendy, J.A., & Lucki, I. Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test. Psychopharmacology (Berl). 183, 257-264 (2005).
14. Karolewicz, B. & Paul, I.A. Group housing of mice increases immobility and antidepressant sensitivity in the forced swim and tail suspension tests. European Journal of Pharmacology. 415, 197-201,doi:10.1016/s0014-2999(01)00830-5 (2001).
15. Lad, H.V., Liu, L., Paya-Cano, J.L., Fernandes, C., & Schalkwyk, L.C. Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping. Mammalian. Genome. 18, 482-491, doi:10.1007/s00335-007-9029-1 (2007).
16. Liu, X. & Gershenfeld, H.K. Genetic differences in the tail-suspension test and its relationship to imipramine response among 11 inbred strains of mice. Biol. Psychiatry. 49, 575-581 (2001).
17. Ripoll, N., David, D.J., Dailly, E., Hascoet, M., & Bourin, M. Antidepressant-like effects in various mice strains in the tail suspension test. Behav. Brain. Res. 143, 193-200 (2003).
18. Mineur, Y.S., Belzung, C., & Crusio, W.E. Effects of unpredictable chronic mild stress on anxiety and depression-like behavior in mice. Behav. Brain. Res. 175, 43-50 (2006).
19. Thierry, B., Stéru, L., Simon, P., & Porsolt, R.D. The tail suspension test: Ethical considerations. Psychopharmacology. 90, 284-285, doi:10.1007/bf00181261 (1986).
20. Cryan, J.F., Mombereau, C., & Vassout, A. The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci. Biobehav. Rev. 29, 571-625 (2005).
21. O'Leary, O.F. & Cryan, J.F. In Mood and Anxiety Related Phenotypes in Mice. Gould, T.D., ed., Vol. 42,119-137, Humana Press, (2009).
22. Detke, M.J., Johnson, J., & Lucki, I. Acute and Chronic Antidepressant Drug Treatment in the Rat Forced Swimming Test Model of Depression. Experimental and Clinical Psychopharmacology. 5, 107-112 (1997).
23. Rupniak, N.M.J. Animal models of depression: challenges from a drug development perspective. Behavioural Pharmacology. 14, 385-390 (2003).
24. Strekalova, T. & Steinbusch, H. In Mood and Anxiety related phenotypes in mice: Characterization using behavioral tests. 42, 153-176 (2009).
25. Bartolomucci, A., Fuchs, E., Koolhaas, J.M. & Ohl, F. In Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests. 42, 261-275 (2009).
26. Samuels, B.A. &Hen, R. In Mood and Anxiety Related Phenotypes in Mice: Characterization Using Behavioral Tests. 63, 107-121 (2011).
27. Juszczak, G.R., et al. The usage of video analysis system for detection of immobility in the tail suspension test in mice. Pharmacology Biochemistry and Behavior. 85, 332-338, doi:10.1016/j.pbb.2006.08.016 (2006).
28. Crowley, J.J., Jones, M.D., O'Leary, O.F., & Lucki, I. Automated tests for measuring the effects of antidepressants in mice. Pharmacology Biochemistry and Behavior. 78, 269-274, doi:10.1016/j.pbb.2004.03.014 (2004).
29. Gould, T.D., et al. Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. Neuropharmacology. 54, 577-587 (2008).
30. Gould, T.D., Dao, D.T., & Kovacsics, C.E. In Mood and Anxiety Related Phenotypes in mice: characterization using behavioral tests. Gould, T.D., ed., Vol. 42, Humana Press, (2009).