Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 21, 2014, Pages

  Masouleh, Behzad Kharabi ^a,c   Geng, Huimin ^a   Hurtz, Christian ^a   Chan, Lai N ^a   Logan, Aaron C ^b   Chang, Mi Sook ^d   Huang, Chuanxin ^e   Swaminathan, Srividya ^a   Sun, Haibo ^f   Paietta, Elisabeth ^g   Melnick, Ari M ^e   Koeffler, Phillip ^f   Müschen, Markus ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d CHILDREN S HOSPITAL LOS ANGELES   (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f CEDARS SINAI MEDICAL CENTER   (United States)

^g ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR 2; BCR ABL PROTEIN; HEAT SHOCK PROTEIN 70; PRE B CELL RECEPTOR; PROTEIN BCL 6; STAT5 PROTEIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; ONCOGENE N RAS; PRIORITY JOURNAL; UNFOLDED PROTEIN RESPONSE;

ADULT; ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BETA-GALACTOSIDASE; BLOTTING, WESTERN; CELL DIFFERENTIATION; CHILD; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FLOW CYTOMETRY; GENE DELETION; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HETEROGRAFTS; HUMANS; KAPLAN-MEIER ESTIMATE; MICE; MICROARRAY ANALYSIS; MOLECULAR SEQUENCE DATA; PRECURSOR B-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN-SERINE-THREONINE KINASES; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; SEQUENCE ANALYSIS, RNA; TRANSCRIPTION FACTORS; UNFOLDED PROTEIN RESPONSE;

EID: 84901649604     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1400958111     Document Type: Article

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