Microencapsulation of mechano growth factor e peptide for sustained delivery and bioactivity maintenance

International Journal of Pharmaceutics

Volumn 469, Issue 1, 2014, Pages 214-221

  Niu, Xufeng ^a   Chen, Pin ^a   Jia, Xiaoling ^a   Wang, Lizhen ^a   Li, Ping ^a   Yang, Li ^b   Wang, Yuanliang ^b   Fan, Yubo ^a  

^a BEIHANG UNIVERSITY   (China)

^b CHONGQING UNIVERSITY   (China)

Author keywords

Bioactivity; Chitosan; Mechano growth factor; Microsphere; Sustained delivery

Indexed keywords

ALKALINE PHOSPHATASE; CHITOSAN; GROWTH FACTOR; MECHANO GROWTH FACTOR E PEPTIDE; MICROSPHERE; PEPTIDE E; TRIPOLYPHOSPHATE; UNCLASSIFIED DRUG; CROSS LINKING REAGENT; DELAYED RELEASE FORMULATION; DRUG CARRIER; POLYPHOSPHATE; SOMATOMEDIN C; TRIPHOSPHORIC ACID;

ARTICLE; BIODEGRADABILITY; BIODEGRADATION; BIOLOGICAL ACTIVITY; BIOMECHANICS; BONE REGENERATION; BONE REMODELING; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CROSS LINKING; DRUG DELIVERY SYSTEM; EMULSION; HYDROGEN BOND; HYDROLYSIS; IN VITRO STUDY; MICROENCAPSULATION; MICROGRAVITY; MICROMORPHOLOGY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; STATIC ELECTRICITY; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; WEIGHT REDUCTION; 3T3 CELL LINE; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; FEASIBILITY STUDY; INFRARED SPECTROSCOPY; KINETICS; MEDICINAL CHEMISTRY; METABOLISM; MOUSE; OSTEOBLAST; PHARMACEUTICS; PROCEDURES; SOLUBILITY;

3T3 CELLS; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; FEASIBILITY STUDIES; HYDROLYSIS; INSULIN-LIKE GROWTH FACTOR I; KINETICS; MICE; MICROSPHERES; OSTEOBLASTS; PARTICLE SIZE; POLYPHOSPHATES; SOLUBILITY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 84901639785     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.04.054     Document Type: Article

References (32)

1. M. Amidi, E. Mastrobattista, W. Jiskoot, and W.E. Hennink Chitosan-based delivery systems for protein therapeutics and antigens Advanced Drug Delivery Reviews 62 2010 59 82
2. S. Boddohi, and M.J. Kipper Engineering nanoassemblies of polysaccharides Advanced Materials 22 2010 2998 3016
3. X. Chen, B. Zhang, Y. Wang, C. Xian, L. Yang, M. Deng, Q. Peng, and Y. Li Mechano-growth factor E peptide inhibits the differentiation and mineralization of osteoblasts Archives of Oral Biology 57 2012 720 727
4. J.M. Collins, P.H. Goldspink, and B. Russell Migration and proliferation of human mesenchymal stem cells is stimulated by different regions of the mechano-growth factor prohormone Journal of Molecular and Cellular Cardiology 49 2010 1042 1045
5. A. Completo, F. Fonseca, and J.A. Simoes Strain shielding in proximal tibia of stemmed knee prosthesis: experimental study Journal of Biomechanics 41 2008 560 566 (Pubitemid 351179715)
6. Z. Dai, F. Wu, E.W. Yeung, and Y. Li IGF-IEc expression, regulation and biological function in different tissues Growth Hormone and IGF Research 20 2010 275 281
7. M. Deng, B. Zhang, K. Wang, F. Liu, H. Xiao, J. Zhao, P. Liu, Y. Li, F. Lin, and Y. Wang Mechano growth factor E peptide promotes osteoblasts proliferation and bone-defect healing in rabbits International Orthopaedics 35 2011 1099 1106
8. R.T. Franceschi, and G. Xiao Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways Journal of Cellular Biochemistry 88 2003 446 454 (Pubitemid 36158266)
9. B. Ghosh, and M.W. Urban Self-repairing oxetane-substituted chitosan polyurethane networks Science 323 2009 1458 1460
10. G. Goldspink Mechanical signals, IGF-I gene splicing, and muscle adaptation Physiology 20 2005 232 238 (Pubitemid 41215197)
11. J. Hu, and P.X. Ma Nano-fibrous tissue engineering scaffolds capable of growth factor delivery Pharmaceutical Research 28 2011 1273 1281
12. G. Karsenty, and M. Ferron The contribution of bone to whole-organism physiology Nature 481 2012 314 320
13. Y.M. Kolambkar, K.M. Dupont, J.D. Boerckel, N. Huebsch, D.J. Mooney, D.W. Hutmacher, and R.E. Guldberg An alginate-based hybrid system for growth factor delivery in the functional repair of large bone defects Biomaterials 32 2011 65 74
14. T. Komori, H. Yagi, S. Nomura, A. Yamaguchi, K. Sasaki, K. Deguchi, Y. Shimizu, R.T. Bronson, Y.H. Gao, M. Inada, M. Sato, R. Okamoto, Y. Kitamura, S. Yoshiki, and T. Kishimoto Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts Cell 89 1997 755 764 (Pubitemid 27516178)
15. Y. Li, B. Zhang, C. Ruan, P. Wang, J. Sun, J. Pan, and Y. Wang Synthesis, characterization, and biocompatibility of a novel biomimetic material based on MGF-Ct24E modified poly(d,l-lactic acid) Journal of Biomedical Materials Research Part A 100 2012 3496 3502
16. Y. Luo, B. Zhang, and W. Cheng Preparation, characterization and evaluation of selenite-loaded chitosan/TPP nanoparticles with or without zein coating Carbohydrate Polymers 82 2010 942 951
17. A. Musaro, C. Giacinti, G. Borsellino, G. Dobrowolny, L. Pelosi, L. Cairns, S. Ottolenghi, G. Cossu, G. Bernardi, L. Battistini, M. Molinaro, and N. Rosenthal Stem cell-mediated muscle regeneration is enhanced by local isoform of insulin-like growth factor 1 Proceedings of the National Academy of Sciences of the United States of America 101 2004 1206 1210 (Pubitemid 38182667)
18. N. Nabavi, A. Khandani, A. Camirand, and R.E. Harrison Effects of microgravity on osteoclast bone resorption and osteoblast cytoskeletal organization and adhesion Bone 49 2011 965 974
19. A. Nasti, N.M. Zaki, P. de Leonardis, S. Ungphaiboon, P. Sansongsak, M.G. Rimoli, and N. Tirelli Chitosan/TPP and chitosan/TPP-hyaluronic acid nanoparticles: systematic optimisation of the preparative process and preliminary biological evaluation Pharmaceutical Research 26 2009 1918 1930
20. T. Niu, and C.J. Rosen The insulin-like growth factor-I gene and osteoporosis: a critical appraisal Gene 361 2005 38 56 (Pubitemid 41506932)
21. X. Niu, Q. Feng, M. Wang, X. Guo, and Q. Zheng In vitro degradation and release behavior of porous poly(lactic acid) scaffolds containing chitosan microspheres as a carrier for BMP-2-derived synthetic peptide Polymer Degradation and Stability 94 2009 176 182
22. X. Niu, Q. Feng, M. Wang, X. Guo, and Q. Zheng Preparation and characterization of chitosan microspheres for controlled release of synthetic oligopeptide derived from BMP-2 Journal of Microencapsulation 26 2009 297 305
23. X. Niu, Q. Feng, M. Wang, X. Guo, and Q. Zheng Porous nano-HA/collagen/PLLA scaffold containing chitosan microspheres for controlled delivery of synthetic peptide derived from BMP-2 Journal of Controlled Release 134 2009 111 117
24. X. Niu, Y. Fan, X. Liu, X. Li, P. Li, J. Wang, Z. Sha, and Q. Feng Repair of bone defect in femoral condyle using microencapsulated chitosan, nanohydroxyapatite/collagen and poly(l-lactide)-based microsphere-scaffold delivery system Artificial Organs 35 2011 E119 E128
25. X. Niu, L. Wang, P. Chen, X. Li, G. Zhou, Q. Feng, and Y. Fan Emulsion self-assembly synthesis of chitosan/poly(lactic-co-glycolic acid) stimuli-responsive amphiphiles Macromolecular Chemistry and Physics 214 2013 700 706
26. Q. Peng, Y. Wang, J. Qiu, B. Zhang, J. Sun, Y. Lv, and L. Yang A novel mechanical loading model for studying the distributions of strain and mechano-growth factor expression Archives of Biochemistry and Biophysics 511 2011 8 13
27. A. Rampino, M. Borgogna, P. Blasi, B. Bellich, and A. Cesaro Chitosan nanoparticles: preparation, size evolution and stability International Journal of Pharmaceutics 455 2013 219 228
28. E. Seeman, and P.D. Delmas Bone quality - the material and structural basis of bone strength and fragility New England Journal of Medicine 354 2006 2250 2261
29. S. Vimal, G. Taju, K.S.N. Nambi, S.A. Majeed, V.S. Babu, M. Ravi, and A.S.S. Hameed Synthesis and characterization of CS/TPP nanoparticles for oral delivery of gene in fish Aquaculture 358-359 2012 14 22
30. C. Wennberg, L. Hessle, P. Lundberg, S. Mauro, S. Narisawa, U.H. Lerner, and J.L. Millan Functional characterization of osteoblasts and osteoclasts from alkaline phosphatase knockout mice Journal of Bone and Mineral Research 15 2000 1879 1888
31. M. Zayzafoon, V.E. Meyers, and J.M. McDonald Microgravity: the immune response and bone Immunological Reviews 208 2005 267 280 (Pubitemid 41746398)
32. W. Zeng, J. Huang, X. Hu, W. Xiao, M. Rong, Z. Yuan, and Z. Luo Ionically cross-linked chitosan microspheres for controlled release of bioactive nerve growth factor International Journal of Pharmaceutics 421 2011 283 290