Effects of microgravity on osteoclast bone resorption and osteoblast cytoskeletal organization and adhesion

Bone

Volumn 49, Issue 5, 2011, Pages 965-974

  Nabavi, Noushin ^a   Khandani, Arian ^b   Camirand, Anne ^c   Harrison, Rene E ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Adhesion; Cytoskeleton; Microgravity; Osteoblast; Osteoclast

Indexed keywords

F ACTIN; PAXILLIN; TUBULIN; VINCULIN; ZYXIN;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CELL SHAPE; CONTROLLED STUDY; CYTOARCHITECTURE; CYTOSKELETON; FOCAL ADHESION; MICROGRAVITY; MICROTUBULE; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOCLAST RESORPTION PIT; OSTEOLYSIS; PROTEIN LOCALIZATION; STRESS FIBER;

ANIMALS; BONE RESORPTION; CELL ADHESION; CELL PROLIFERATION; CELLS, CULTURED; CYTOSKELETON; MICE; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; OSTEOCLASTS; WEIGHTLESSNESS;

EID: 80054831997     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.07.036     Document Type: Article

References (62)

1. Vico L., et al. Osteobiology, strain, and microgravity. Part II: studies at the tissue level. Calcif Tissue Int 2001, 68(1):1-10.
2. Carmeliet G., Bouillon R. The effect of microgravity on morphology and gene expression of osteoblasts in vitro. FASEB J 1999, 13(9001):129-134.
3. Tamma R., et al. Microgravity during spaceflight directly affects in vitro osteoclastogenesis and bone resorption. FASEB J 2009, 23(8):2549-2554.
4. Van Loon J.J.W.A., et al. Decreased mineralization and increased calcium release in isolated fetal mouse long bones under near weightlessness. J Bone Miner Res 1995, 10(4):550-557.
5. Marie P.J., et al. Osteobiology, strain, and microgravity: Part I. Studies at the cellular level. Calcif Tissue Int 2000, 67(1):2-9.
6. Klein-Nulend J., et al. Microgravity and bone cell mechanosensitivity. Adv Space Res 2003, 32(8):1551-1559.
7. Baek K., et al. Food restriction and simulated microgravity: effects on bone and serum leptin. J Appl Physiol 2008, 104(4):1086-1093.
8. Martin T.J., Sims N.A. Osteoclast-derived activity in the coupling of bone formation to resorption. Trends Mol Med 2005, 11(2):76-81.
9. Tabony J., Pochon N., Papaseit C. Microtubule self-organisation depends upon gravity. Adv Space Res 2001, 28(4):529-535.
10. Robert C., et al. Self organization of the microtubule network. A diffusion based model. Biol Cell 1990, 68(1-3):177-181.
11. Tabony J., et al. Biological self-organization by way of microtubule reaction diffusion processes. Langmuir 2002, 18(19):7196-7207.
12. Ingber D.E., Tensegrity I. Cell structure and hierarchical systems biology. J Cell Sci 2003, 116(7):1157-1173.
13. Berezovska O.P., et al. Changes in the numbers of osteoclasts in newts under conditions of microgravity. Adv Space Res 1998, 21(8-9):1059-1063.
14. Nogales E. Structural insights into microtubule function. Annu Rev Biophys Biomol Struct 2001, 30(1):397-420.
15. Janmey P.A. The cytoskeleton and cell signaling: component localization and mechanical coupling. Physiol Rev 1998, 78(3):763-781.
16. Tolomeo J.A., Holley M.C. Mechanics of microtubule bundles in pillar cells from the inner ear. Biophys J 1997, 73(4):2241-2247.
17. Khawaja S., Gundersen G.G., Bulinski J.C. Enhanced stability of microtubules enriched in detyrosinated tubulin is not a direct function of detyrosination level. J Cell Biol 1988, 106(1):141-149.
18. Ingber D.E. Tensegrity: the architectural basis of cellular mechanotransduction. Annu Rev Physiol 1997, 59(1):575-599.
19. Burridge K., et al. Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu Rev Cell Biol 1988, 4(1):487-525.
20. Schwartz M.A., Schaller M.D., Ginsberg M.H. Integrins: emerging paradigms of signal transduction. Annu Rev Cell Dev Biol 1995, 11(1):549-599.
21. Tamada M., Sheetz M.P., Sawada Y. Activation of a signaling cascade by cytoskeleton stretch. Dev Cell 2004, 7(5):709-718.
22. Norvell S.M., et al. Fluid shear stress induction of COX-2 protein and prostaglandin release in cultured MC3T3-E1 osteoblasts does not require intact microfilaments or microtubules.2003. J Appl Physiol 2004, 96(3):957-966.
23. Bellows C.G., et al. Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations. Calcif Tissue Int 1986, 38(3):143-154.
24. Salim A., et al. Transient changes in oxygen tension inhibit osteogenic differentiation and Runx2 expression in osteoblasts. J Biol Chem 2004, 279(38):40007-40016.
25. Patel P.C., Harrison R.E. Membrane ruffles capture C3bi-opsonized particles in activated macrophages. Mol Biol Cell 2008, 19(11):4628-4639.
26. Tamma R., et al. Microgravity during spaceflight directly affects in vitro osteoclastogenesis and bone resorption. FASEB J 2009, 23(8):2549-2554.
27. Ezratty E.J., Partridge M.A., Gundersen G.G. Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase. Nat Cell Biol 2005, 7(6):581-590.
28. Liu S., Calderwood D.A., Ginsberg M.H. Integrin cytoplasmic domain-binding proteins. J Cell Sci 2000, 113(20):3563-3571.
29. Turner C.E., Glenney J.R., Burridge K. Paxillin: a new vinculin-binding protein present in focal adhesions. J Cell Biol 1990, 111(3):1059-1068.
30. Zaidel-Bar R., et al. Early molecular events in the assembly of matrix adhesions at the leading edge of migrating cells. J Cell Sci 2003, 116(22):4605-4613.
31. Ingber D.E. Tensegrity: the architectural basis of cellular mechanotransduction. Annu Rev Physiol 1997, 59(1):575-599.
32. Guignandon A., et al. Focal contacts organization in osteoblastic cells under microgravity and cyclic deformation conditions. Adv Space Res 2003, 32(8):1561-1567.
33. Hughes-Fulford M., Lewis M.L. Effects of microgravity on osteoblast growth activation. Exp Cell Res 1996, 224(1):103-109.
34. Terpos E., Dimopoulos M.A. Myeloma bone disease: pathophysiology and management. Ann Oncol 2005, 16(8):1223-1231.
35. Casuccio C. Concerning osteoporosis. J Bone Joint Surg Br 1962, 44-B(3):453-463.
36. Kazuo Y., et al. Decreased cellular activity and replicative capacity of osteoblastic cells isolated from the periarticular bone of rheumatoid arthritis patients compared with osteoarthritis patients. Arthritis Rheum 2000, 43(10):2178-2188.
37. Gravallese E.M. Bone destruction in arthritis. Ann Rheum Dis 2002, 61:84-86.
38. Ellington J.K., et al. Mechanisms ofStaphylococcus aureusinvasion of cultured osteoblasts. Microb Pathog 1999, 26(6):317-323.
39. Shalhoub V., et al. Gene expression during skeletal development in three osteopetrotic rat mutations. Evidence for osteoblast abnormalities. J Biol Chem 1991, 266(15):9847-9856.
40. Manolagas S.C. Cellular and molecular mechanisms of osteoporosis. Aging Clin Exp Res 1998, 10(3):182-190.
41. Roodman G.D. Biology of osteoclast activation in cancer. J Clin Oncol 2001, 19(15):3562-3571.
42. Destaing O., et al. A novel Rho-mDia2-HDAC6 pathway controls podosome patterning through microtubule acetylation in osteoclasts. J Cell Sci 2005, 118(13):2901-2911.
43. Papaseit C., Pochon N., Tabony J. Microtubule self-organization is gravity-dependent. Proc Natl Acad Sci USA 2000, 97(15):8364-8368.
44. Efimov A., et al. Paxillin-dependent stimulation of microtubule catastrophes at focal adhesion sites. J Cell Sci 2008, 121(2):196-204.
45. Guignandon A., et al. Cell cycling determines integrin-mediated adhesion in osteoblastic ROS 17/2.8 cells exposed to space-related conditions. FASEB J 2001, 15(11):2036-2038.
46. Carragher N.O., Frame M.C. Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion. Trends Cell Biol 2004, 14(5):241-249.
47. Goldmann W.H. Kinetic determination of focal adhesion protein formation. Biochem Biophys Res Commun 2000, 271(2):553-557.
48. Tang D.D., et al. The focal adhesion protein paxillin regulates contraction in canine tracheal smooth muscle. J Physiol 2002, 542(2):501-513.
49. Ziegler W.H., Liddington R.C., Critchley D.R. The structure and regulation of vinculin. Trends Cell Biol 2006, 16(9):453-460.
50. Starr D.A. Communication between the cytoskeleton and the nuclear envelope to position the nucleus. Mol Biosyst 2007, 3(9):583-589.
51. Valentijn A.J., Zouq N., Gilmore A.P. Anoikis. Biochem Soc Trans 2004, 32:421-425.
52. Grossmann J., et al. Apoptotic signaling during initiation of detachment-induced apoptosis ("Anoikis") of primary human intestinal epithelial cells. Cell Growth Differ 2001, 12(3):147-155.
53. Bikle D.D., Halloran B.P., Morey-Holton E. Impact of skeletal unloading on bone formation: Role of systemic and local factors. Acta Astronaut 1994, 33:119-129.
54. Morey-Holton E.R., Globus R.K. Hindlimb unloading of growing rats: a model for predicting skeletal changes during space flight. Bone 1998, 22(5 Suppl):83S-88S.
55. Sakata T., et al. Trabecular bone turnover and bone marrow cell development in tail-suspended mice. J Bone Miner Res 1999, 14(9):1596-1604.
56. Saxena R., et al. Modeled microgravity and hindlimb unloading sensitize osteoclast precursors to RANKL-mediated osteoclastogenesis. J Bone Miner Metab 2011, 29(1):111-122.
57. Guignandon A., et al. Shape changes of osteoblastic cells under gravitational variations during parabolic flight-relationship with PGE2 synthesis. Cell Struct Funct 1995, 20(5):369-375.
58. Sambandam Y., et al. Microarray profile of gene expression during osteoclast differentiation in modelled microgravity. J Cell Biochem 2010, 111(5):1179-1187.
59. Sarkar D., et al. Rotation in clinostat results in apoptosis of osteoblastic ROS 17/2.8 cells. J Gravit Physiol 2000, 7(2):P71-P72.
60. Sarkar D., et al. Culture in vector-averaged gravity under clinostat rotation results in apoptosis of osteoblastic ROS 17/2.8 cells. J Bone Miner Res 2000, 15(3):489-498.
61. Rucci N., et al. Characterization of the osteoblast-like cell phenotype under microgravity conditions in the NASA-approved Rotating Wall Vessel bioreactor (RWV). J Cell Biochem 2002, 85(1):167-179.
62. Bucaro M.A., et al. The effect of simulated microgravity on osteoblasts is independent of the induction of apoptosis. J Cell Biochem 2007, 102(2):483-495.