Mechano growth factor e peptide promotes osteoblasts proliferation and bone-defect healing in rabbits

International Orthopaedics

Volumn 35, Issue 7, 2011, Pages 1099-1106

  Deng, Moyuan ^a   Zhang, Bingbing ^a   Wang, Ke ^b   Liu, Feng ^b   Xiao, Hualiang ^b   Zhao, Jianhua ^b   Liu, Peng ^b   Li, Yuxiao ^a   Lin, Fuchun ^a   Wang, Yuanliang ^a  

^a CHONGQING UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; MECHANO GROWTH FACTOR E PEPTIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALLUS; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL DENSITY; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; ENZYME ACTIVATION; EXPERIMENTAL RABBIT; FIBROBLAST; FRACTURE HEALING; HAVERSIAN CANAL; HISTOLOGY; IN VIVO STUDY; LOW DRUG DOSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOID; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; VASCULARIZATION;

ANIMALS; BONE REGENERATION; CELL CYCLE; CELL LINE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DNA; INSULIN-LIKE GROWTH FACTOR I; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OSTEOBLASTS; OSTEOGENESIS; RABBITS; WOUND HEALING;

EID: 79961173310     PISSN: 03412695     EISSN: 14325195     Source Type: Journal    
DOI: 10.1007/s00264-010-1141-2     Document Type: Article

References (24)

1. M Skarli SY Yang P Bouloux G Goldspink 1998 Upregulation and alternative splicing of the IGF-I gene in the rabbit heart following a brief pressure/volume overload J Physiol 9 92 193
2. S Yang M Alnaqeeb H Simpson G Goldspink 1996 Cloning and characterization of an IGF-1 isoform expressed in skeletal muscle subjected to stretch J Muscle Res Cell Motil 17 487 495 8884603 10.1007/BF00123364 1:CAS:528: DyaK28XmtFChsbg%3D (Pubitemid 26298531)
3. M Hill A Wernig G Goldspink 2003 Muscle satellite (stem) cell activation during local tissue injury and repair J Anat 203 89 99 12892408 10.1046/j.1469-7580.2003.00195.x 1:CAS:528:DC%2BD3sXmsFGntrk%3D (Pubitemid 36889245)
4. J Dluzniewska A Sarnowska G Goldspink B Zabłocka 2005 A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF) in brain ischemia FASEB J 19 1896 1898 16144956 1:CAS:528:DC%2BD2MXht1emtrvK (Pubitemid 41598787)
5. M Dimitrios K Haralampos MS Protopapas GM Stelios K Michael 2006 Insulin-like growth factor-1 isoform mRNA expression in women with endometriosis: eutopic endometrium versus endometriotic cyst Ann NY Acad Sci 1092 434 439 10.1196/annals.1365.042 (Pubitemid 47092362)
6. JL Olesen KM Heinemeier A Flyvbjerg M Kjaer 2006 Expression of insulin-like growth factor I, insulin-like growth factor binding proteins and collagen mRNA in mechanically loaded plantaris tendon Appl Physiol 101 183 188 10.1152/japplphysiol.00636.2005 1:CAS:528:DC%2BD28XnsFWjsLk%3D (Pubitemid 44035364)
7. K Ates SY Yang RW Orrell P Simons 2007 The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle FEBS Lett 581 2727 2732 17531227 10.1016/j.febslet.2007.05.030 1:CAS:528:DC%2BD2sXmtFOiu70%3D (Pubitemid 46829121)
8. P Mills JF Lafreniere JP Tremblay 2007 A new pro-migratory activity on human myogenic precursor cells for a synthetic peptide within the E domain of the mechano growth factor Exp Cell Res 313 5275 5237 10.1016/j.yexcr.2006.10.032 (Pubitemid 46186304)
9. A Quesada P Micevych A Handforth 2009 C-terminal mechano growth factor protects dopamine neurons: A novel peptide that induces heme oxygenase-1 Exp Neurol 220 255 266 19735655 10.1016/j.expneurol.2009.08.029 1:CAS:528: DC%2BD1MXhsVGnt7zJ
10. V Carpenter K Matthews SY Yang G Goldspink 2008 Mechano-growth factor reduces loss of cardiac function in acute myocardial infarction Heart Lung Circ 17 33 39 17581790 10.1016/j.hlc.2007.04.013 (Pubitemid 350246337)
11. A Abbaspour S Takata Y Matsui N Yasui 2008 Continuous infusion of insulin-like growth factor-I into the epiphysis of the tibia Int Orthop 32 395 402 17431620 10.1007/s00264-007-0336-7 (Pubitemid 351569735)
12. LL Tang CY Xian YL Wang 2006 The MGF expression of osteoblasts in response to mechanical overload Arch Oral Biol 51 1080 1085 16934742 10.1016/j.archoralbio.2006.06.009 1:CAS:528:DC%2BD28Xht1Sjs7nK (Pubitemid 44692652)
13. B Zhang P Jiang C Xian L Tang Y Wang 2008 Expression of mechano-growth factor in Eschericha coli and activity analysis Sheng Wu Gong Xue Bao 24 1180 1185 1:CAS:528:DC%2BD1MXjtV2ms7g%3D Chinese
14. H Eckardt KS Christensen M Lind 2005 Recombinant human bone morphogenetic protein 2 enhances bone healing in an experimental model of fractures at risk of non-union Injury 36 489 494 15755429 10.1016/j.injury.2004.10.019 (Pubitemid 40332331)
15. L Meinel E Zoidis R Schneider 2003 Localized insulin-like growth factor I delivery to enhance new bone formation Bone 33 660 672 14555272 10.1016/S8756-3282(03)00207-2 1:CAS:528:DC%2BD3sXnvVersLw%3D (Pubitemid 37222393)
16. W Yao W Yao Yu Jun T Bozic 2008 IGF-I improved bone mineral density and body composition of weaver mutant mice Growth Horm IGF Res 18 517 525 18550407 10.1016/j.ghir.2008.04.006 1:CAS:528:DC%2BD1cXht1ejurrL
17. F Forriola UG Longob V Denaro 2009 Platelet-rich plasma, rhOP-1® (rhBMP-7) and frozen rib allograft for the reconstruction of bony mandibular defects in sheep. A pilot experimental study Injury Int J Care Injured 40 S3 S44 S49
18. LA McMahon PJ Prendergast VA Campbell 2008 A comparison of the involvement of p38, ERK1/2 and PI3K in growth factor-induced chondrogenic differentiation of mesenchymal stem cells Biochem Biophys Res Commun 18 990 995 10.1016/j.bbrc.2008.01.160
19. E Vicky S MacRae F Ahmed C Farquharson 2007 IGF-I signalling in bone growth: Inhibitory actions of dexamethasone and IL-1b Growth Horm IGF Res 7 435 439 (Pubitemid 47324309)
20. A Stavropoulou A Halapas A Sourla 2009 IGF-1 expression in infarcted myocardium and MGF E peptide actions in rat cardiomyocytes in vitro Mol Med 15 127 135 19295919 10.2119/molmed.2009.00012 1:CAS:528:DC%2BD1MXnvF2ls7w%3D
21. A Raucci P Bellosta R Grassi C Basilico A Mansukhani 2008 Osteoblast proliferation or differentiation is regulated by relative strengths of opposing signaling pathways J Cell Physiol 215 442 451 17960591 10.1002/jcp.21323 1:CAS:528:DC%2BD1cXksFWksLw%3D (Pubitemid 351468956)
22. S Morshed L Corrales T Miclau 2008 Outcome assessment in clinical trials of fracture-healing J Bone Joint Surg 90 62 67 18292359 10.2106/JBJS.G.01556 (Pubitemid 351329123)
23. S Mohan 1993 Insulin-like growth factor binding proteins in bone cell regulation Growth Reg 3 67 70 1:CAS:528:DyaK3sXltlWltLs%3D (Pubitemid 23131740)
24. E Circi S Akpinar IC Tuncay 2009 Biomechanical and histological comparison of the influence of oestrogen deficient state on tendon healing potential in rats Int Orthop 33 1461 1466 19387642 10.1007/s00264-009-0778-1